Khajanchi2017 - Uniform Persistence and Global Stability for a Brain Tumor and Immune System Interaction Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_unresolved_tumor_observable_1",
        "label": "Initial Unresolved Tumor Observable 1",
        "units": "native source value",
        "default": 100000,
        "maps_to": "immunology_sbml_khajanchi2017_uniform_persistence_and_global_sta_biomd0000000921_model.initial_unresolved_tumor_observable_1",
        "description": "Initial Unresolved Tumor Observable 1. Sets the initial value of bundled SBML species `G`."
      },
      {
        "name": "initial_unresolved_tumor_observable_2",
        "label": "Initial Unresolved Tumor Observable 2",
        "units": "native source value",
        "default": 100000,
        "maps_to": "immunology_sbml_khajanchi2017_uniform_persistence_and_global_sta_biomd0000000921_model.initial_unresolved_tumor_observable_2",
        "description": "Initial Unresolved Tumor Observable 2. Sets the initial value of bundled SBML species `M`."
      },
      {
        "name": "initial_unresolved_tumor_observable_3",
        "label": "Initial Unresolved Tumor Observable 3",
        "units": "native source value",
        "default": 1,
        "maps_to": "immunology_sbml_khajanchi2017_uniform_persistence_and_global_sta_biomd0000000921_model.initial_unresolved_tumor_observable_3",
        "description": "Initial Unresolved Tumor Observable 3. Sets the initial value of bundled SBML species `C_T`."
      },
      {
        "name": "initial_unresolved_tumor_observable_4",
        "label": "Initial Unresolved Tumor Observable 4",
        "units": "native source value",
        "default": 5000,
        "maps_to": "immunology_sbml_khajanchi2017_uniform_persistence_and_global_sta_biomd0000000921_model.initial_unresolved_tumor_observable_4",
        "description": "Initial Unresolved Tumor Observable 4. Sets the initial value of bundled SBML species `T_beta`."
      },
      {
        "name": "initial_gamma",
        "label": "Initial Gamma",
        "units": "native source value",
        "default": 9000,
        "maps_to": "immunology_sbml_khajanchi2017_uniform_persistence_and_global_sta_biomd0000000921_model.initial_gamma",
        "description": "Initial Gamma. Sets the initial value of bundled SBML species `I_gamma`."
      },
      {
        "name": "the_proliferative_enhancement_effect_of_macrophagesby_interferon_gama_and_negati",
        "label": "The Proliferative Enhancement Effect Of Macrophagesby Interferon Gama And Negati",
        "units": "native source value",
        "default": 10500,
        "maps_to": "immunology_sbml_khajanchi2017_uniform_persistence_and_global_sta_biomd0000000921_model.the_proliferative_enhancement_effect_of_macrophagesby_interferon_gama_and_negati",
        "description": "The Proliferative Enhancement Effect Of Macrophagesby Interferon Gama And Negati. Sets bundled SBML parameter `k4`."
      },
      {
        "name": "the_rate_of_change_of_cytotoxic_t_lymphocytes_whose_stimulation_is_followed_by_g",
        "label": "The Rate Of Change Of Cytotoxic T Lymphocytes Whose Stimulation Is Followed By G",
        "units": "native source value",
        "default": 2000,
        "maps_to": "immunology_sbml_khajanchi2017_uniform_persistence_and_global_sta_biomd0000000921_model.the_rate_of_change_of_cytotoxic_t_lymphocytes_whose_stimulation_is_followed_by_g",
        "description": "The Rate Of Change Of Cytotoxic T Lymphocytes Whose Stimulation Is Followed By G. Sets bundled SBML parameter `k5`."
      },
      {
        "name": "clearance_of_cytotoxic_t_lymphocytes_due_to_their_interaction_with_glioma_cells",
        "label": "Clearance Of Cytotoxic T Lymphocytes Due To Their Interaction With Glioma Cells",
        "units": "native source value",
        "default": 334450,
        "maps_to": "immunology_sbml_khajanchi2017_uniform_persistence_and_global_sta_biomd0000000921_model.clearance_of_cytotoxic_t_lymphocytes_due_to_their_interaction_with_glioma_cells",
        "description": "Clearance Of Cytotoxic T Lymphocytes Due To Their Interaction With Glioma Cells. Sets bundled SBML parameter `k3`."
      }
    ],
    "outputs": [
      {
        "name": "unresolved_tumor_observable_1",
        "maps_to": "immunology_sbml_khajanchi2017_uniform_persistence_and_global_sta_biomd0000000921_model.unresolved_tumor_observable_1"
      },
      {
        "name": "unresolved_tumor_observable_2",
        "maps_to": "immunology_sbml_khajanchi2017_uniform_persistence_and_global_sta_biomd0000000921_model.unresolved_tumor_observable_2"
      },
      {
        "name": "unresolved_tumor_observable_3",
        "maps_to": "immunology_sbml_khajanchi2017_uniform_persistence_and_global_sta_biomd0000000921_model.unresolved_tumor_observable_3"
      },
      {
        "name": "unresolved_tumor_observable_4",
        "maps_to": "immunology_sbml_khajanchi2017_uniform_persistence_and_global_sta_biomd0000000921_model.unresolved_tumor_observable_4"
      },
      {
        "name": "gamma",
        "maps_to": "immunology_sbml_khajanchi2017_uniform_persistence_and_global_sta_biomd0000000921_model.gamma"
      },
      {
        "name": "state",
        "maps_to": "immunology_sbml_khajanchi2017_uniform_persistence_and_global_sta_biomd0000000921_model.state"
      },
      {
        "name": "summary",
        "maps_to": "immunology_sbml_khajanchi2017_uniform_persistence_and_global_sta_biomd0000000921_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "immunology_sbml_khajanchi2017_uniform_persistence_and_global_sta_biomd0000000921_model.species_labels"
      }
    ]
  },
  "title": "Khajanchi2017 - Uniform Persistence and Global Stability for a Brain Tumor and Immune System Interaction Lab",
  "models": [
    {
      "path": "owned/models/immunology_sbml_khajanchi2017_uniform_persistence_and_global_sta_biomd0000000921_model",
      "alias": "immunology_sbml_khajanchi2017_uniform_persistence_and_global_sta_biomd0000000921_model",
      "provenance": {
        "owned_path": "owned/models/immunology_sbml_khajanchi2017_uniform_persistence_and_global_sta_biomd0000000921_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.immunology_sbml_khajanchi2017_uniform_persistence_and_global_sta_biomd0000000921_model_state"
      ],
      "from": "immunology_sbml_khajanchi2017_uniform_persistence_and_global_sta_biomd0000000921_model.state"
    },
    {
      "to": [
        "visualisation.immunology_sbml_khajanchi2017_uniform_persistence_and_global_sta_biomd0000000921_model_summary"
      ],
      "from": "immunology_sbml_khajanchi2017_uniform_persistence_and_global_sta_biomd0000000921_model.summary"
    },
    {
      "to": [
        "visualisation.immunology_sbml_khajanchi2017_uniform_persistence_and_global_sta_biomd0000000921_model_species_labels"
      ],
      "from": "immunology_sbml_khajanchi2017_uniform_persistence_and_global_sta_biomd0000000921_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "This paper describes the synergistic interaction between the growth of malignant gliomas and the immune system interactions using a system of coupled ordinary di®erential equations (ODEs). It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
  "schema_version": "2.0"
}