A hub for public biological labs

Two-model lab for Guyton1972 Aldosterone: a core SBML simulator wired into a dedicated visualization sub-model that turns the raw state into friendly timeseries and a plain-language summary. This a model from the article: Circulation: overall regulation. It can be used to explore cardiac dynamics and compare response patterns across conditions.

Martins2013 - True and apparent inhibition ofamyloid fribril formation This model is described in the article: True and apparent inhibition of amyloid fibril formation. It can be used to explore systemsbiology martins2013 true and apparent inhibition dynamics and compare simulation behavior across conditions.

. It can be used to explore systemsbiology chassagnole2001 threonine synthesis BioModels0000000066 dynamics and compare simulation behavior across conditions.

Source-faithful physiology lab for A Primer on Modular Mass Action Modelling with CellML. Public controls and outputs are mapped to real source symbols for source-model physiology.

This model is from the article: Workflow for generating competing hypothesis from models with parameter uncertainty. David Gomez-Cabrero, Albert Compte and Jesper Tegner Interface Focus 6 June 2011 vo.

Source-faithful physiology lab for Fenton, Karma, 2006. Public controls and outputs are mapped to real source symbols for electrophysiology.

This a model from the article: Monte Carlo analysis of an ODE Model of the Sea Urchin Endomesoderm Network. Kühn C, Wierling C, Kühn A, Klipp E, Panopoulou G, Lehrach H, Poustka AJ.

This a model from the article: Intercellular calcium waves mediated by diffusion of inositol trisphosphate: atwo-dimensional model. Sneyd J, Wetton BT, Charles AC, Sanderson MJ.

Clean Biosimulant lab for systems signaling model: Ajay_Bhalla_2007_Bistable. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.

Persistence analysis in a Kolmogorov-type model for cancer-immune system competitionAIP Conference Proceedings 1558, 1797 (2013); https://doi.org/10.1063/1.4825874C. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.

This model originates from BioModels Database: A Database of Annotated Published Models. It is copyright (c) 2005-2009 The BioModels Team.

The model reproduces the calcium oscillation dependent activation-deactivation kinetics of nuclear factor of activated T cells (NFAT) as depicted in Fig 4a of the paper. It can be used to explore systemsbiology fisher2006 ca oscillation dpdnt nfat dynamics and compare simulation behavior across conditions.

Single-model lab wrapper for Ndii2015-transmission dynamics of dengue in the presence of Wolbachia.. Use of the bacterium Wolbachia is an innovative new strategy designed to break the cycle of dengue transmission. There are two main mechanisms by which Wolbachia could achieve this: by reducing the le.

Clean Biosimulant lab for NF-kB pathway signaling. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.

Kerkhoven2013 - Glycolysis and Pentose Phosphate Pathway in T.brucei -MODEL C (with glucosomal ribokinase) There are six models (Model A, B, C, C-fruc, D, D-fruc) described in the paper. It can be used to explore metabolic flux dynamics and compare pathway behavior across conditions.

This mathematical model of the role of the innate immune responses generated by macrophages in the context of anti-tumour oncolytic viral therapies is described in the publication:Nada Almuallem, Dumi. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.

Smallbone2013 - Glycolysis in S.cerevisiae - Iteration 10 This model is described in the article: A model of yeast glycolysis based on a consistent kinetic characterization of all its enzymes Kieran S. It can be used to explore metabolic flux dynamics and compare pathway behavior across conditions.

Source-faithful physiology lab for Mears 1997. Public controls and outputs are mapped to real source symbols for electrophysiology.

This a model from the article: Critical study of and improvements in chromatographic methods for the analysisof type B trichothecenes. Mateo JJ, Llorens A, Mateo R, Jimenez M.

Clean Biosimulant lab for metabolic and hormone-linked signaling. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.

Proctor2017 - Identifying microRNA for muscleregeneration during ageing (Mir143_in_muscle) This model is described in the article: Using computer simulation models to investigate the most promising mi. It can be used to explore systemsbiology proctor2017 identifying microrna for muscle dynamics and compare simulation behavior across conditions.

This model simulates the colonization of the mouse gut with different strains of Yersinia enterocolitica. Thereby it takes the host-immune repsone into account.

Source-faithful physiology lab for Priebe, Beuckelmann, 1998. Public controls and outputs are mapped to real source symbols for electrophysiology.

This is a dynamical model of cancer growth that includes three interacting cell populations of tumor cells, healthy host cells and immune effector cells. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.