About lab
Requires input from Chen2004(BIOMD0000000056) model but did not work correctly even after integrating both models. It can be used to explore systemsbiology a quantitative of the initiation dynamics and compare simulation behavior across conditions.
Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagea-quantitative-model-of-the-initiation-of-dna-replication-in-sac
Created2026-05-17
Updated2026-05-17
systemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisation
Manifest
{
"io": {
"inputs": [
{
"name": "initial_orc_total",
"label": "Initial Orc Total",
"maps_to": "systemsbiology_sbml_a_quantitative_model_of_the_initiation_of_dna_re_model1812050001_model.initial_orc_total",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `ORC_Total`."
},
{
"name": "initial_mcm_total",
"label": "Initial Mcm Total",
"maps_to": "systemsbiology_sbml_a_quantitative_model_of_the_initiation_of_dna_re_model1812050001_model.initial_mcm_total",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `MCM_Total`."
},
{
"name": "initial_cdt1_total",
"label": "Initial Cdt1 Total",
"maps_to": "systemsbiology_sbml_a_quantitative_model_of_the_initiation_of_dna_re_model1812050001_model.initial_cdt1_total",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `CDT1_Total`."
},
{
"name": "initial_cdc45_total",
"label": "Initial Cdc45 Total",
"maps_to": "systemsbiology_sbml_a_quantitative_model_of_the_initiation_of_dna_re_model1812050001_model.initial_cdc45_total",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `CDC45_Total`."
},
{
"name": "initial_orc_p",
"label": "Initial Orc P",
"maps_to": "systemsbiology_sbml_a_quantitative_model_of_the_initiation_of_dna_re_model1812050001_model.initial_orc_p",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `ORC_P`."
},
{
"name": "initial_orc_mcm_dbf4_cdc45",
"label": "Initial Orc Mcm Dbf4 Cdc45",
"maps_to": "systemsbiology_sbml_a_quantitative_model_of_the_initiation_of_dna_re_model1812050001_model.initial_orc_mcm_dbf4_cdc45",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `ORC_MCM_DBF4_CDC45`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_a_quantitative_model_of_the_initiation_of_dna_re_model1812050001_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_a_quantitative_model_of_the_initiation_of_dna_re_model1812050001_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_a_quantitative_model_of_the_initiation_of_dna_re_model1812050001_model.species_labels"
},
{
"name": "orc_total",
"maps_to": "systemsbiology_sbml_a_quantitative_model_of_the_initiation_of_dna_re_model1812050001_model.orc_total"
},
{
"name": "mcm_total",
"maps_to": "systemsbiology_sbml_a_quantitative_model_of_the_initiation_of_dna_re_model1812050001_model.mcm_total"
},
{
"name": "cdt1_total",
"maps_to": "systemsbiology_sbml_a_quantitative_model_of_the_initiation_of_dna_re_model1812050001_model.cdt1_total"
},
{
"name": "cdc45_total",
"maps_to": "systemsbiology_sbml_a_quantitative_model_of_the_initiation_of_dna_re_model1812050001_model.cdc45_total"
},
{
"name": "orc_p",
"maps_to": "systemsbiology_sbml_a_quantitative_model_of_the_initiation_of_dna_re_model1812050001_model.orc_p"
},
{
"name": "orc_mcm_dbf4_cdc45",
"maps_to": "systemsbiology_sbml_a_quantitative_model_of_the_initiation_of_dna_re_model1812050001_model.orc_mcm_dbf4_cdc45"
}
]
},
"tags": [
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "A Quantitative Model Of The Initiation Of Dna Replication In Saccharomyces Cerevisiae Pr Lab",
"models": [
{
"path": "owned/models/systemsbiology_sbml_a_quantitative_model_of_the_initiation_of_dna_re_model1812050001_model",
"alias": "systemsbiology_sbml_a_quantitative_model_of_the_initiation_of_dna_re_model1812050001_model",
"provenance": {
"owned_path": "owned/models/systemsbiology_sbml_a_quantitative_model_of_the_initiation_of_dna_re_model1812050001_model"
}
},
{
"path": "owned/models/visualisation",
"alias": "visualisation",
"provenance": {
"owned_path": "owned/models/visualisation"
}
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_a_quantitative_model_of_the_initiation_of_dna_re_model1812050001_model_state"
],
"from": "systemsbiology_sbml_a_quantitative_model_of_the_initiation_of_dna_re_model1812050001_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_a_quantitative_model_of_the_initiation_of_dna_re_model1812050001_model_summary"
],
"from": "systemsbiology_sbml_a_quantitative_model_of_the_initiation_of_dna_re_model1812050001_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_a_quantitative_model_of_the_initiation_of_dna_re_model1812050001_model_species_labels"
],
"from": "systemsbiology_sbml_a_quantitative_model_of_the_initiation_of_dna_re_model1812050001_model.species_labels"
}
],
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"description": "Requires input from Chen2004(BIOMD0000000056) model but did not work correctly even after integrating both models. It can be used to explore systemsbiology a quantitative of the initiation dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
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