Monro2008 - chemotherapy resistance Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_chemo_sensitive_cells",
        "label": "Chemo-Sensitive Cells",
        "units": "native SBML value",
        "default": 10000000000,
        "maps_to": "oncology_sbml_monro2008_chemotherapy_resistance_biomd0000000776_model.initial_chemo_sensitive_cells",
        "description": "Initial Chemo-Sensitive Cells. Sets the initial value of bundled SBML symbol `S`."
      },
      {
        "name": "initial_chemo_resistant_cells",
        "label": "Chemo-Resistant Cells",
        "units": "native SBML value",
        "default": 200000,
        "maps_to": "oncology_sbml_monro2008_chemotherapy_resistance_biomd0000000776_model.initial_chemo_resistant_cells",
        "description": "Initial Chemo-Resistant Cells. Sets the initial value of bundled SBML symbol `R`."
      },
      {
        "name": "chemotherapy_concentration",
        "label": "Chemotherapy Concentration",
        "units": "native SBML value",
        "default": 2,
        "maps_to": "oncology_sbml_monro2008_chemotherapy_resistance_biomd0000000776_model.chemotherapy_concentration",
        "description": "Chemotherapy Concentration. Overrides bundled SBML parameter `C0`."
      }
    ],
    "outputs": [
      {
        "name": "chemo_sensitive_cells",
        "maps_to": "oncology_sbml_monro2008_chemotherapy_resistance_biomd0000000776_model.chemo_sensitive_cells",
        "description": "Chemo-Sensitive Cells observable. Maps to SBML symbol `S`."
      },
      {
        "name": "chemo_resistant_cells",
        "maps_to": "oncology_sbml_monro2008_chemotherapy_resistance_biomd0000000776_model.chemo_resistant_cells",
        "description": "Chemo-Resistant Cells observable. Maps to SBML symbol `R`."
      },
      {
        "name": "state",
        "maps_to": "oncology_sbml_monro2008_chemotherapy_resistance_biomd0000000776_model.state",
        "description": "Full raw SBML observable record for reproducibility and downstream visualisation."
      },
      {
        "name": "summary",
        "maps_to": "oncology_sbml_monro2008_chemotherapy_resistance_biomd0000000776_model.summary",
        "description": "Change and peak summary across the simulated SBML observables."
      },
      {
        "name": "species_labels",
        "maps_to": "oncology_sbml_monro2008_chemotherapy_resistance_biomd0000000776_model.species_labels",
        "description": "Mapping from selected raw SBML observable symbols to display labels."
      }
    ]
  },
  "tags": [
    "biomodels_ebi",
    "chemotherapy",
    "curated",
    "drug-response",
    "faithful",
    "oncology",
    "pharmacology",
    "physiology",
    "sbml",
    "systemsbiology",
    "tumor-growth"
  ],
  "title": "Monro2008 - chemotherapy resistance Lab",
  "models": [
    {
      "path": "owned/models/oncology_sbml_monro2008_chemotherapy_resistance_biomd0000000776_model",
      "alias": "oncology_sbml_monro2008_chemotherapy_resistance_biomd0000000776_model",
      "provenance": {
        "owned_path": "owned/models/oncology_sbml_monro2008_chemotherapy_resistance_biomd0000000776_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.oncology_sbml_monro2008_chemotherapy_resistance_biomd0000000776_model_state"
      ],
      "from": "oncology_sbml_monro2008_chemotherapy_resistance_biomd0000000776_model.state"
    },
    {
      "to": [
        "visualisation.oncology_sbml_monro2008_chemotherapy_resistance_biomd0000000776_model_summary"
      ],
      "from": "oncology_sbml_monro2008_chemotherapy_resistance_biomd0000000776_model.summary"
    },
    {
      "to": [
        "visualisation.oncology_sbml_monro2008_chemotherapy_resistance_biomd0000000776_model_species_labels"
      ],
      "from": "oncology_sbml_monro2008_chemotherapy_resistance_biomd0000000776_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "The paper describes a model of resistance of cancer to chemotherapy. Created by COPASI 4.25 (Build 207) This model is described in the article: Modelling chemotherapy resistance in palliation and fail.",
  "schema_version": "2.0"
}