dePillis2005 - A validated mathematical model of cell-mediated immune response to tumor growth Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_unresolved_tumor_observable_1",
        "label": "Initial Unresolved Tumor Observable 1",
        "units": "native source value",
        "default": 100,
        "maps_to": "immunology_sbml_depillis2005_a_validated_mathematical_model_of_c_model1907260001_model.initial_unresolved_tumor_observable_1",
        "description": "Initial Unresolved Tumor Observable 1. Sets the initial value of bundled SBML species `T`."
      },
      {
        "name": "initial_unresolved_tumor_observable_2",
        "label": "Initial Unresolved Tumor Observable 2",
        "units": "native source value",
        "default": 1000,
        "maps_to": "immunology_sbml_depillis2005_a_validated_mathematical_model_of_c_model1907260001_model.initial_unresolved_tumor_observable_2",
        "description": "Initial Unresolved Tumor Observable 2. Sets the initial value of bundled SBML species `N`."
      },
      {
        "name": "initial_unresolved_tumor_observable_3",
        "label": "Initial Unresolved Tumor Observable 3",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_depillis2005_a_validated_mathematical_model_of_c_model1907260001_model.initial_unresolved_tumor_observable_3",
        "description": "Initial Unresolved Tumor Observable 3. Sets the initial value of bundled SBML species `L`."
      },
      {
        "name": "tumor_killing_natural_killer_rate",
        "label": "Tumor Killing Natural Killer Rate",
        "units": "native source value",
        "default": 3.23e-7,
        "maps_to": "immunology_sbml_depillis2005_a_validated_mathematical_model_of_c_model1907260001_model.tumor_killing_natural_killer_rate",
        "description": "Tumor Killing Natural Killer Rate. Sets bundled SBML parameter `c`."
      }
    ],
    "outputs": [
      {
        "name": "unresolved_tumor_observable_1",
        "maps_to": "immunology_sbml_depillis2005_a_validated_mathematical_model_of_c_model1907260001_model.unresolved_tumor_observable_1"
      },
      {
        "name": "unresolved_tumor_observable_2",
        "maps_to": "immunology_sbml_depillis2005_a_validated_mathematical_model_of_c_model1907260001_model.unresolved_tumor_observable_2"
      },
      {
        "name": "unresolved_tumor_observable_3",
        "maps_to": "immunology_sbml_depillis2005_a_validated_mathematical_model_of_c_model1907260001_model.unresolved_tumor_observable_3"
      },
      {
        "name": "state",
        "maps_to": "immunology_sbml_depillis2005_a_validated_mathematical_model_of_c_model1907260001_model.state"
      },
      {
        "name": "summary",
        "maps_to": "immunology_sbml_depillis2005_a_validated_mathematical_model_of_c_model1907260001_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "immunology_sbml_depillis2005_a_validated_mathematical_model_of_c_model1907260001_model.species_labels"
      }
    ]
  },
  "title": "dePillis2005 - A validated mathematical model of cell-mediated immune response to tumor growth Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "immunology_sbml_depillis2005_a_validated_mathematical_model_of_c_model1907260001_model"
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.immunology_sbml_depillis2005_a_validated_mathematical_model_of_c_model1907260001_model_state"
      ],
      "from": "immunology_sbml_depillis2005_a_validated_mathematical_model_of_c_model1907260001_model.state"
    },
    {
      "to": [
        "visualisation.immunology_sbml_depillis2005_a_validated_mathematical_model_of_c_model1907260001_model_summary"
      ],
      "from": "immunology_sbml_depillis2005_a_validated_mathematical_model_of_c_model1907260001_model.summary"
    },
    {
      "to": [
        "visualisation.immunology_sbml_depillis2005_a_validated_mathematical_model_of_c_model1907260001_model_species_labels"
      ],
      "from": "immunology_sbml_depillis2005_a_validated_mathematical_model_of_c_model1907260001_model.species_labels"
    }
  ],
  "package": "depillis2005-a-validated-mathematical-model-of-cell-mediated",
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "version": "1.0.1",
  "description": "This model describes interactions between a tumour and the immune system, with specific emphasis on the role of natural killer and CD8-positive T cells in tumor surveillance. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
  "schema_version": "2.0"
}