Maier2022 - Stochastic Dynamics of Type I Interferon Responses Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_cytosolic_stat2_irf9_complex",
        "label": "Initial Cytosolic Stat2 Irf9 Complex",
        "units": "native source value",
        "default": 231.21387283237,
        "maps_to": "immunology_sbml_maier2022_stochastic_dynamics_of_type_i_interfer_model2210070001_model.initial_cytosolic_stat2_irf9_complex",
        "description": "Initial Cytosolic Stat2 Irf9 Complex. Sets the initial value of bundled SBML species `STAT2_IRF9_c`."
      },
      {
        "name": "initial_nuclear_stat2_irf9_complex",
        "label": "Initial Nuclear Stat2 Irf9 Complex",
        "units": "native source value",
        "default": 2407.40740740741,
        "maps_to": "immunology_sbml_maier2022_stochastic_dynamics_of_type_i_interfer_model2210070001_model.initial_nuclear_stat2_irf9_complex",
        "description": "Initial Nuclear Stat2 Irf9 Complex. Sets the initial value of bundled SBML species `STAT2_IRF9_n`."
      },
      {
        "name": "initial_interferon",
        "label": "Initial Interferon",
        "units": "native source value",
        "default": 11560.6936416185,
        "maps_to": "immunology_sbml_maier2022_stochastic_dynamics_of_type_i_interfer_model2210070001_model.initial_interferon",
        "description": "Initial Interferon. Sets the initial value of bundled SBML species `IFN`."
      },
      {
        "name": "initial_cytosolic_stat1",
        "label": "Initial Cytosolic Stat1",
        "units": "native source value",
        "default": 983430.057803468,
        "maps_to": "immunology_sbml_maier2022_stochastic_dynamics_of_type_i_interfer_model2210070001_model.initial_cytosolic_stat1",
        "description": "Initial Cytosolic Stat1. Sets the initial value of bundled SBML species `STAT1_c`."
      },
      {
        "name": "initial_pstat1",
        "label": "Initial Pstat1",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_maier2022_stochastic_dynamics_of_type_i_interfer_model2210070001_model.initial_pstat1",
        "description": "Initial Pstat1. Sets the initial value of bundled SBML species `pSTAT1`."
      }
    ],
    "outputs": [
      {
        "name": "cytosolic_stat2_irf9_complex",
        "maps_to": "immunology_sbml_maier2022_stochastic_dynamics_of_type_i_interfer_model2210070001_model.cytosolic_stat2_irf9_complex"
      },
      {
        "name": "nuclear_stat2_irf9_complex",
        "maps_to": "immunology_sbml_maier2022_stochastic_dynamics_of_type_i_interfer_model2210070001_model.nuclear_stat2_irf9_complex"
      },
      {
        "name": "interferon",
        "maps_to": "immunology_sbml_maier2022_stochastic_dynamics_of_type_i_interfer_model2210070001_model.interferon"
      },
      {
        "name": "cytosolic_stat1",
        "maps_to": "immunology_sbml_maier2022_stochastic_dynamics_of_type_i_interfer_model2210070001_model.cytosolic_stat1"
      },
      {
        "name": "pstat1",
        "maps_to": "immunology_sbml_maier2022_stochastic_dynamics_of_type_i_interfer_model2210070001_model.pstat1"
      },
      {
        "name": "state",
        "maps_to": "immunology_sbml_maier2022_stochastic_dynamics_of_type_i_interfer_model2210070001_model.state"
      },
      {
        "name": "summary",
        "maps_to": "immunology_sbml_maier2022_stochastic_dynamics_of_type_i_interfer_model2210070001_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "immunology_sbml_maier2022_stochastic_dynamics_of_type_i_interfer_model2210070001_model.species_labels"
      }
    ]
  },
  "title": "Maier2022 - Stochastic Dynamics of Type I Interferon Responses Lab",
  "models": [
    {
      "path": "owned/models/immunology_sbml_maier2022_stochastic_dynamics_of_type_i_interfer_model2210070001_model",
      "alias": "immunology_sbml_maier2022_stochastic_dynamics_of_type_i_interfer_model2210070001_model",
      "provenance": {
        "owned_path": "owned/models/immunology_sbml_maier2022_stochastic_dynamics_of_type_i_interfer_model2210070001_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.immunology_sbml_maier2022_stochastic_dynamics_of_type_i_interfer_model2210070001_model_state"
      ],
      "from": "immunology_sbml_maier2022_stochastic_dynamics_of_type_i_interfer_model2210070001_model.state"
    },
    {
      "to": [
        "visualisation.immunology_sbml_maier2022_stochastic_dynamics_of_type_i_interfer_model2210070001_model_summary"
      ],
      "from": "immunology_sbml_maier2022_stochastic_dynamics_of_type_i_interfer_model2210070001_model.summary"
    },
    {
      "to": [
        "visualisation.immunology_sbml_maier2022_stochastic_dynamics_of_type_i_interfer_model2210070001_model_species_labels"
      ],
      "from": "immunology_sbml_maier2022_stochastic_dynamics_of_type_i_interfer_model2210070001_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "Maier2022 - Stochastic Dynamics of Type I Interferon ResponsesOur study aims to determine whether and how biochemical noise affects the information transduced in the JAK-STAT signaling pathway and inv. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
  "schema_version": "2.0"
}