Bonhoeffer2000 - Risks Benefits Structured Antiretroviral Drug Therapy Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_ctl",
        "label": "Initial CTL",
        "maps_to": "physiology_cellml_bonhoeffer_rembiszewski_ortiz_nixon_2000_2dc_model.initial_ctl",
        "description": "Initial value for CTL. Maps to source symbol `E`. Units: dimensionless. Naming evidence: source metadata names `E` as `CTL`.",
        "accepted_units": [
          "dimensionless"
        ]
      },
      {
        "name": "initial_infected_cells",
        "label": "Initial Infected Cells",
        "maps_to": "physiology_cellml_bonhoeffer_rembiszewski_ortiz_nixon_2000_2dc_model.initial_infected_cells",
        "description": "Initial value for Infected Cells. Maps to source symbol `I`. Units: dimensionless. Naming evidence: source metadata names `I` as `infected cells`.",
        "accepted_units": [
          "dimensionless"
        ]
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Selected Source State",
        "maps_to": "physiology_cellml_bonhoeffer_rembiszewski_ortiz_nixon_2000_2dc_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation Summary",
        "maps_to": "physiology_cellml_bonhoeffer_rembiszewski_ortiz_nixon_2000_2dc_model.summary"
      },
      {
        "name": "trajectory",
        "label": "Source Trajectory",
        "maps_to": "physiology_cellml_bonhoeffer_rembiszewski_ortiz_nixon_2000_2dc_model.trajectory"
      },
      {
        "name": "variable_labels",
        "label": "Observable Labels",
        "maps_to": "physiology_cellml_bonhoeffer_rembiszewski_ortiz_nixon_2000_2dc_model.variable_labels"
      },
      {
        "name": "ctl",
        "label": "CTL",
        "maps_to": "physiology_cellml_bonhoeffer_rembiszewski_ortiz_nixon_2000_2dc_model.ctl",
        "description": "CTL. Maps to source symbol `E`. Units: dimensionless. Naming evidence: source metadata names `E` as `CTL`."
      },
      {
        "name": "infected_cells",
        "label": "Infected Cells",
        "maps_to": "physiology_cellml_bonhoeffer_rembiszewski_ortiz_nixon_2000_2dc_model.infected_cells",
        "description": "Infected Cells. Maps to source symbol `I`. Units: dimensionless. Naming evidence: source metadata names `I` as `infected cells`."
      },
      {
        "name": "susceptible_target_cells",
        "label": "Susceptible Target Cells",
        "maps_to": "physiology_cellml_bonhoeffer_rembiszewski_ortiz_nixon_2000_2dc_model.susceptible_target_cells",
        "description": "Susceptible Target Cells. Maps to source symbol `T`. Units: dimensionless. Naming evidence: source metadata names `T` as `susceptible target cells`."
      },
      {
        "name": "model_parameter_k",
        "label": "Model Parameter K (source K)",
        "maps_to": "physiology_cellml_bonhoeffer_rembiszewski_ortiz_nixon_2000_2dc_model.model_parameter_k",
        "description": "Model Parameter K (source K). Maps to source symbol `K`. Units: dimensionless. Naming evidence: source symbol is dimensionless but lacks enough evidence for a biological label."
      },
      {
        "name": "rate_constant_d_e",
        "label": "Rate Constant D E (source dE)",
        "maps_to": "physiology_cellml_bonhoeffer_rembiszewski_ortiz_nixon_2000_2dc_model.rate_constant_d_e",
        "description": "Rate Constant D E (source dE). Maps to source symbol `dE`. Units: first_order_rate_constant. Naming evidence: units identify a rate constant but not a fuller biological role."
      },
      {
        "name": "rate_constant_d_i",
        "label": "Rate Constant D I (source dI)",
        "maps_to": "physiology_cellml_bonhoeffer_rembiszewski_ortiz_nixon_2000_2dc_model.rate_constant_d_i",
        "description": "Rate Constant D I (source dI). Maps to source symbol `dI`. Units: first_order_rate_constant. Naming evidence: units identify a rate constant but not a fuller biological role."
      }
    ]
  },
  "title": "Bonhoeffer2000 - Risks Benefits Structured Antiretroviral Drug Therapy Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "physiology_cellml_bonhoeffer_rembiszewski_ortiz_nixon_2000_2dc_model",
      "parameters": {
        "model_path": "data/bonhoeffer_rembiszewski_ortiz_nixon_2000_a.cellml",
        "integration_step": 0.01
      }
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.physiology_cellml_bonhoeffer_rembiszewski_ortiz_nixon_2000_2dc_model_state"
      ],
      "from": "physiology_cellml_bonhoeffer_rembiszewski_ortiz_nixon_2000_2dc_model.state"
    },
    {
      "to": [
        "visualisation.physiology_cellml_bonhoeffer_rembiszewski_ortiz_nixon_2000_2dc_model_summary"
      ],
      "from": "physiology_cellml_bonhoeffer_rembiszewski_ortiz_nixon_2000_2dc_model.summary"
    },
    {
      "to": [
        "visualisation.physiology_cellml_bonhoeffer_rembiszewski_ortiz_nixon_2000_2dc_model_trajectory"
      ],
      "from": "physiology_cellml_bonhoeffer_rembiszewski_ortiz_nixon_2000_2dc_model.trajectory"
    },
    {
      "to": [
        "visualisation.physiology_cellml_bonhoeffer_rembiszewski_ortiz_nixon_2000_2dc_model_variable_labels"
      ],
      "from": "physiology_cellml_bonhoeffer_rembiszewski_ortiz_nixon_2000_2dc_model.variable_labels"
    }
  ],
  "package": "bonhoeffer2000-risks-benefits-structured-antiretroviral-3bb30621",
  "runtime": {
    "duration": 0.01,
    "settle_steps": 1,
    "initial_inputs": {},
    "communication_step": 0.01
  },
  "version": "1.0.0",
  "description": "Source-faithful physiology lab for Bonhoeffer, Rembiszewski, Ortiz, Nixon, 2000. Public controls and outputs are mapped to real source symbols for pharmacokinetics.",
  "schema_version": "2.0"
}