Winter2017 - Brain Energy Metabolism with PPP Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_brain_energy_state_1",
        "units": "native SBML value",
        "default": 0.040323291746644,
        "maps_to": "metabolism_sbml_winter2017_brain_energy_metabolism_with_ppp_biomd0000000627_model.initial_brain_energy_state_1",
        "description": "Initial condition for brain energy state 1. Maps to bundled SBML symbol `species_23`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_co2",
        "units": "native SBML value",
        "default": 0.0121467082533562,
        "maps_to": "metabolism_sbml_winter2017_brain_energy_metabolism_with_ppp_biomd0000000627_model.initial_co2",
        "description": "Initial condition for co2. Maps to bundled SBML symbol `species_24`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_glucose",
        "units": "native SBML value",
        "default": 0.0253903826849856,
        "maps_to": "metabolism_sbml_winter2017_brain_energy_metabolism_with_ppp_biomd0000000627_model.initial_glucose",
        "description": "Initial condition for glucose. Maps to bundled SBML symbol `species_25`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_lactate",
        "units": "native SBML value",
        "default": 0.00188912996259375,
        "maps_to": "metabolism_sbml_winter2017_brain_energy_metabolism_with_ppp_biomd0000000627_model.initial_lactate",
        "description": "Initial condition for lactate. Maps to bundled SBML symbol `species_26`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_brain_energy_state_5",
        "units": "native SBML value",
        "default": 0.000262913971209081,
        "maps_to": "metabolism_sbml_winter2017_brain_energy_metabolism_with_ppp_biomd0000000627_model.initial_brain_energy_state_5",
        "description": "Initial condition for brain energy state 5. Maps to bundled SBML symbol `dHb`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      }
    ],
    "outputs": [
      {
        "name": "brain_energy_state_1",
        "maps_to": "metabolism_sbml_winter2017_brain_energy_metabolism_with_ppp_biomd0000000627_model.brain_energy_state_1"
      },
      {
        "name": "co2",
        "maps_to": "metabolism_sbml_winter2017_brain_energy_metabolism_with_ppp_biomd0000000627_model.co2"
      },
      {
        "name": "glucose",
        "maps_to": "metabolism_sbml_winter2017_brain_energy_metabolism_with_ppp_biomd0000000627_model.glucose"
      },
      {
        "name": "lactate",
        "maps_to": "metabolism_sbml_winter2017_brain_energy_metabolism_with_ppp_biomd0000000627_model.lactate"
      },
      {
        "name": "brain_energy_state_5",
        "maps_to": "metabolism_sbml_winter2017_brain_energy_metabolism_with_ppp_biomd0000000627_model.brain_energy_state_5"
      },
      {
        "name": "observable_values",
        "maps_to": "metabolism_sbml_winter2017_brain_energy_metabolism_with_ppp_biomd0000000627_model.observable_values"
      },
      {
        "name": "run_summary",
        "maps_to": "metabolism_sbml_winter2017_brain_energy_metabolism_with_ppp_biomd0000000627_model.run_summary"
      },
      {
        "name": "observable_labels",
        "maps_to": "metabolism_sbml_winter2017_brain_energy_metabolism_with_ppp_biomd0000000627_model.observable_labels"
      }
    ]
  },
  "title": "Winter2017 - Brain Energy Metabolism with PPP Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "metabolism_sbml_winter2017_brain_energy_metabolism_with_ppp_biomd0000000627_model",
      "parameters": {
        "model_path": "data/BIOMD0000000627.xml",
        "integration_step": 0.1
      }
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.metabolism_sbml_winter2017_brain_energy_metabolism_with_ppp_biomd0000000627_model_observable_values"
      ],
      "from": "metabolism_sbml_winter2017_brain_energy_metabolism_with_ppp_biomd0000000627_model.observable_values"
    },
    {
      "to": [
        "visualisation.metabolism_sbml_winter2017_brain_energy_metabolism_with_ppp_biomd0000000627_model_run_summary"
      ],
      "from": "metabolism_sbml_winter2017_brain_energy_metabolism_with_ppp_biomd0000000627_model.run_summary"
    },
    {
      "to": [
        "visualisation.metabolism_sbml_winter2017_brain_energy_metabolism_with_ppp_biomd0000000627_model_observable_labels"
      ],
      "from": "metabolism_sbml_winter2017_brain_energy_metabolism_with_ppp_biomd0000000627_model.observable_labels"
    }
  ],
  "package": "winter2017-brain-energy-metabolism-with-ppp",
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "version": "1.0.0",
  "description": "Winter2017 - Brain Energy Metabolism with PPP This model is described in the article: Mathematical analysis of the influence of brain metabolism on the BOLD signal in Alzheimer's disease Felix Winter1. It can be used to explore metabolic flux dynamics and compare pathway behavior across conditions.",
  "schema_version": "2.0"
}