About lab
Koo et al. (2013) model of nitric oxide (NO) production downstream of shear-stress-driven calcium and eNOS activation in endothelial cells.
Runtime
Duration600
Comms Step10
Runs
Total4
Completed4
Failed0
Metadata
Packagekoo2013-no-production
Created2026-05-04
Updated2026-06-13
biomechanicsendothelialshear-stressnitric-oxidemechanotransductionsbmlbiomodels_ebifaithfulvisualisationkoo2013other
Manifest
{
"io": {
"inputs": [
{
"name": "cytosolic_calcium",
"maps_to": "koo2013_shear_stress_no_production.cytosolic_calcium"
},
{
"name": "integration_step",
"maps_to": "koo2013_shear_stress_no_production.integration_step"
}
],
"outputs": [
{
"name": "active_eNOS",
"maps_to": "koo2013_shear_stress_no_production.active_eNOS"
},
{
"name": "nitric_oxide",
"maps_to": "koo2013_shear_stress_no_production.nitric_oxide"
},
{
"name": "state",
"maps_to": "koo2013_shear_stress_no_production.state"
},
{
"name": "summary",
"maps_to": "koo2013_shear_stress_no_production.summary"
}
]
},
"title": "Koo2013 Shear-Stress Induced NO Production Lab",
"models": [
{
"path": "models/core",
"alias": "koo2013_shear_stress_no_production",
"parameters": {
"model_path": "data/BIOMD0000000467.xml",
"integration_step": 1
}
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.koo2013_shear_stress_no_production_active_eNOS"
],
"from": "koo2013_shear_stress_no_production.active_eNOS"
},
{
"to": [
"visualisation.koo2013_shear_stress_no_production_nitric_oxide"
],
"from": "koo2013_shear_stress_no_production.nitric_oxide"
},
{
"to": [
"visualisation.koo2013_shear_stress_no_production_state"
],
"from": "koo2013_shear_stress_no_production.state"
},
{
"to": [
"visualisation.koo2013_shear_stress_no_production_summary"
],
"from": "koo2013_shear_stress_no_production.summary"
}
],
"package": "koo2013-no-production",
"runtime": {
"duration": 600,
"initial_inputs": {},
"communication_step": 10
},
"version": "1.0.0",
"description": "Koo et al. (2013) model of nitric oxide (NO) production downstream of shear-stress-driven calcium and eNOS activation in endothelial cells.",
"schema_version": "2.0"
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