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Proctor2017 Role Of Micrornas In Osteoarthritis 5 Lab

About lab

Proctor2017- Role of microRNAs inosteoarthritis (miR140-IL1 coherent feed forward) This model is described in the article: Computer simulation models as a tool to investigate the role of microRNAs in. It can be used to explore systemsbiology proctor2017 role of micrornas in dynamics and compare simulation behavior across conditions.

Runtime

Duration1
Comms Step0.1

Runs

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Completed0
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Metadata

Packageproctor2017-role-of-micrornas-in-osteoarthritis-5-lab
Created2026-05-17
Updated2026-05-17
generegulationsystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_mi_r140",
        "label": "Initial Mi R140",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170001_model.initial_mi_r140",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `miR140`."
      },
      {
        "name": "initial_model_state_il1",
        "label": "Initial Model State IL1",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170001_model.initial_model_state_il1",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `IL1`."
      },
      {
        "name": "initial_mi_r140_gene",
        "label": "Initial Mi R140 Gene",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170001_model.initial_mi_r140_gene",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `miR140_gene`."
      },
      {
        "name": "initial_sink",
        "label": "Initial Sink",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170001_model.initial_sink",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Sink`."
      },
      {
        "name": "initial_adamts5_mrna_mi_r140",
        "label": "Initial Adamts5 MRNA Mi R140",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170001_model.initial_adamts5_mrna_mi_r140",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `ADAMTS5_mRNA_miR140`."
      },
      {
        "name": "initial_adamts5_mrna",
        "label": "Initial Adamts5 MRNA",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170001_model.initial_adamts5_mrna",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `ADAMTS5_mRNA`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170001_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170001_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170001_model.species_labels"
      },
      {
        "name": "mi_r140",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170001_model.mi_r140"
      },
      {
        "name": "il1",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170001_model.il1"
      },
      {
        "name": "mi_r140_gene",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170001_model.mi_r140_gene"
      },
      {
        "name": "sink",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170001_model.sink"
      },
      {
        "name": "adamts5_mrna_mi_r140",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170001_model.adamts5_mrna_mi_r140"
      },
      {
        "name": "adamts5_mrna",
        "maps_to": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170001_model.adamts5_mrna"
      }
    ]
  },
  "tags": [
    "generegulation",
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Proctor2017 Role Of Micrornas In Osteoarthritis 5 Lab",
  "models": [
    {
      "path": "owned/models/systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170001_model",
      "alias": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170001_model",
      "provenance": {
        "owned_path": "owned/models/systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170001_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170001_model_state"
      ],
      "from": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170001_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170001_model_summary"
      ],
      "from": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170001_model.summary"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170001_model_species_labels"
      ],
      "from": "systemsbiology_sbml_proctor2017_role_of_micrornas_in_osteoarthritis_model1705170001_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "Proctor2017- Role of microRNAs inosteoarthritis (miR140-IL1 coherent feed forward) This model is described in the article: Computer simulation models as a tool to investigate the role of microRNAs in. It can be used to explore systemsbiology proctor2017 role of micrornas in dynamics and compare simulation behavior across conditions.",
  "schema_version": "2.0"
}

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