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Stern1999 - Local Control Cardiac Excitation Contraction Coupling Lab

About lab

Source-faithful physiology lab for Stern, Song, Sham, Yang, Boheler, Rios, 1999. Public controls and outputs are mapped to real source symbols for electrophysiology.

Runtime

Duration0.01
Comms Step0.01
Settle Steps1

Runs

Total0
Completed0
Failed0

Metadata

Packagestern1999-local-control-cardiac-excitation-contraction-coupling
Created2026-05-23
Updated2026-05-23
physiologycellmlphysiomefaithfulvisualisationother

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_calcium_release_channel_state_ri",
        "label": "Initial Calcium Release Channel State Ri (source RI)",
        "maps_to": "physiology_cellml_stern_song_sham_yang_boheler_rios_1999_sternsongshamyangbohelerrios1999_model.initial_calcium_release_channel_state_ri",
        "description": "Initial value for Calcium Release Channel State Ri (source RI). Maps to source symbol `RI`. Units: dimensionless. Naming evidence: cardiac excitation-contraction context supports a conservative calcium-release-channel state label.",
        "accepted_units": [
          "dimensionless"
        ]
      },
      {
        "name": "initial_receptor",
        "label": "Initial Receptor",
        "maps_to": "physiology_cellml_stern_song_sham_yang_boheler_rios_1999_sternsongshamyangbohelerrios1999_model.initial_receptor",
        "description": "Initial value for Receptor. Maps to source symbol `R`. Units: dimensionless. Naming evidence: source metadata names `R` as `Receptor`.",
        "accepted_units": [
          "dimensionless"
        ]
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Selected Source State",
        "maps_to": "physiology_cellml_stern_song_sham_yang_boheler_rios_1999_sternsongshamyangbohelerrios1999_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation Summary",
        "maps_to": "physiology_cellml_stern_song_sham_yang_boheler_rios_1999_sternsongshamyangbohelerrios1999_model.summary"
      },
      {
        "name": "trajectory",
        "label": "Source Trajectory",
        "maps_to": "physiology_cellml_stern_song_sham_yang_boheler_rios_1999_sternsongshamyangbohelerrios1999_model.trajectory"
      },
      {
        "name": "variable_labels",
        "label": "Observable Labels",
        "maps_to": "physiology_cellml_stern_song_sham_yang_boheler_rios_1999_sternsongshamyangbohelerrios1999_model.variable_labels"
      },
      {
        "name": "calcium_release_channel_state_ri",
        "label": "Calcium Release Channel State Ri (source RI)",
        "maps_to": "physiology_cellml_stern_song_sham_yang_boheler_rios_1999_sternsongshamyangbohelerrios1999_model.calcium_release_channel_state_ri",
        "description": "Calcium Release Channel State Ri (source RI). Maps to source symbol `RI`. Units: dimensionless. Naming evidence: cardiac excitation-contraction context supports a conservative calcium-release-channel state label."
      },
      {
        "name": "calcium_concentration",
        "label": "Calcium Concentration",
        "maps_to": "physiology_cellml_stern_song_sham_yang_boheler_rios_1999_sternsongshamyangbohelerrios1999_model.calcium_concentration",
        "description": "Calcium Concentration. Maps to source symbol `Ca`. Units: millimolar. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "intracellular_potassium",
        "label": "Intracellular Potassium",
        "maps_to": "physiology_cellml_stern_song_sham_yang_boheler_rios_1999_sternsongshamyangbohelerrios1999_model.intracellular_potassium",
        "description": "Intracellular Potassium. Maps to source symbol `ki`. Units: second_order_rate_constant. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "receptor",
        "label": "Receptor",
        "maps_to": "physiology_cellml_stern_song_sham_yang_boheler_rios_1999_sternsongshamyangbohelerrios1999_model.receptor",
        "description": "Receptor. Maps to source symbol `R`. Units: dimensionless. Naming evidence: source metadata names `R` as `Receptor`."
      },
      {
        "name": "inactive_state",
        "label": "Inactive State",
        "maps_to": "physiology_cellml_stern_song_sham_yang_boheler_rios_1999_sternsongshamyangbohelerrios1999_model.inactive_state",
        "description": "Inactive State. Maps to source symbol `I`. Units: dimensionless. Naming evidence: source metadata names `I` as `Inactive state`."
      },
      {
        "name": "open_state",
        "label": "Open State",
        "maps_to": "physiology_cellml_stern_song_sham_yang_boheler_rios_1999_sternsongshamyangbohelerrios1999_model.open_state",
        "description": "Open State. Maps to source symbol `O`. Units: dimensionless. Naming evidence: source metadata names `O` as `Open state`."
      }
    ]
  },
  "title": "Stern1999 - Local Control Cardiac Excitation Contraction Coupling Lab",
  "models": [
    {
      "path": "owned/models/physiology_cellml_stern_song_sham_yang_boheler_rios_1999_sternsongshamyangbohelerrios1999_model",
      "alias": "physiology_cellml_stern_song_sham_yang_boheler_rios_1999_sternsongshamyangbohelerrios1999_model",
      "parameters": {
        "model_path": "data/stern_song_sham_yang_boheler_rios_1999.cellml",
        "integration_step": 0.01
      },
      "provenance": {
        "owned_path": "owned/models/physiology_cellml_stern_song_sham_yang_boheler_rios_1999_sternsongshamyangbohelerrios1999_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.physiology_cellml_stern_song_sham_yang_boheler_rios_1999_sternsongshamyangbohelerrios1999_model_state"
      ],
      "from": "physiology_cellml_stern_song_sham_yang_boheler_rios_1999_sternsongshamyangbohelerrios1999_model.state"
    },
    {
      "to": [
        "visualisation.physiology_cellml_stern_song_sham_yang_boheler_rios_1999_sternsongshamyangbohelerrios1999_model_summary"
      ],
      "from": "physiology_cellml_stern_song_sham_yang_boheler_rios_1999_sternsongshamyangbohelerrios1999_model.summary"
    },
    {
      "to": [
        "visualisation.physiology_cellml_stern_song_sham_yang_boheler_rios_1999_sternsongshamyangbohelerrios1999_model_trajectory"
      ],
      "from": "physiology_cellml_stern_song_sham_yang_boheler_rios_1999_sternsongshamyangbohelerrios1999_model.trajectory"
    },
    {
      "to": [
        "visualisation.physiology_cellml_stern_song_sham_yang_boheler_rios_1999_sternsongshamyangbohelerrios1999_model_variable_labels"
      ],
      "from": "physiology_cellml_stern_song_sham_yang_boheler_rios_1999_sternsongshamyangbohelerrios1999_model.variable_labels"
    }
  ],
  "runtime": {
    "duration": 0.01,
    "settle_steps": 1,
    "initial_inputs": {},
    "communication_step": 0.01
  },
  "description": "Source-faithful physiology lab for Stern, Song, Sham, Yang, Boheler, Rios, 1999. Public controls and outputs are mapped to real source symbols for electrophysiology.",
  "schema_version": "2.0"
}

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