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Elowitz2000 - Synthetic Oscillatory Network Transcriptional Regulators Lab

About lab

Source-faithful physiology lab for Elowitz, Leibler, 2000. Public controls and outputs are mapped to real source symbols for oscillatory physiology.

Runtime

Duration0.01
Comms Step0.01
Settle Steps1

Runs

Total0
Completed0
Failed0

Metadata

Packageelowitz2000-synthetic-oscillatory-network-transcriptional-regula
Created2026-05-23
Updated2026-05-23
physiologycellmlphysiomefaithfulvisualisationother

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_m_tet_r",
        "label": "Initial M Tet R",
        "maps_to": "physiology_cellml_elowitz_leibler_2000_elowitzleibler2000_model.initial_m_tet_r",
        "description": "Initial value for M Tet R. Maps to source symbol `M_tetR`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name.",
        "accepted_units": [
          "dimensionless"
        ]
      },
      {
        "name": "initial_model_state_m_cl",
        "label": "Initial Model State M Cl (source M_cl)",
        "maps_to": "physiology_cellml_elowitz_leibler_2000_elowitzleibler2000_model.initial_model_state_m_cl",
        "description": "Initial value for Model State M Cl (source M_cl). Maps to source symbol `M_cl`. Units: dimensionless. Naming evidence: source symbol is dimensionless but lacks enough evidence for a biological label.",
        "accepted_units": [
          "dimensionless"
        ]
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Selected Source State",
        "maps_to": "physiology_cellml_elowitz_leibler_2000_elowitzleibler2000_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation Summary",
        "maps_to": "physiology_cellml_elowitz_leibler_2000_elowitzleibler2000_model.summary"
      },
      {
        "name": "trajectory",
        "label": "Source Trajectory",
        "maps_to": "physiology_cellml_elowitz_leibler_2000_elowitzleibler2000_model.trajectory"
      },
      {
        "name": "variable_labels",
        "label": "Observable Labels",
        "maps_to": "physiology_cellml_elowitz_leibler_2000_elowitzleibler2000_model.variable_labels"
      },
      {
        "name": "m_tet_r",
        "label": "M Tet R",
        "maps_to": "physiology_cellml_elowitz_leibler_2000_elowitzleibler2000_model.m_tet_r",
        "description": "M Tet R. Maps to source symbol `M_tetR`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "model_state_m_cl",
        "label": "Model State M Cl (source M_cl)",
        "maps_to": "physiology_cellml_elowitz_leibler_2000_elowitzleibler2000_model.model_state_m_cl",
        "description": "Model State M Cl (source M_cl). Maps to source symbol `M_cl`. Units: dimensionless. Naming evidence: source symbol is dimensionless but lacks enough evidence for a biological label."
      },
      {
        "name": "model_state_p_cl",
        "label": "Model State P Cl (source P_cl)",
        "maps_to": "physiology_cellml_elowitz_leibler_2000_elowitzleibler2000_model.model_state_p_cl",
        "description": "Model State P Cl (source P_cl). Maps to source symbol `P_cl`. Units: dimensionless. Naming evidence: source symbol is dimensionless but lacks enough evidence for a biological label."
      },
      {
        "name": "p_tet_r",
        "label": "P Tet R",
        "maps_to": "physiology_cellml_elowitz_leibler_2000_elowitzleibler2000_model.p_tet_r",
        "description": "P Tet R. Maps to source symbol `P_tetR`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "m_lacl",
        "label": "M Lacl",
        "maps_to": "physiology_cellml_elowitz_leibler_2000_elowitzleibler2000_model.m_lacl",
        "description": "M Lacl. Maps to source symbol `M_lacl`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "p_lacl",
        "label": "P Lacl",
        "maps_to": "physiology_cellml_elowitz_leibler_2000_elowitzleibler2000_model.p_lacl",
        "description": "P Lacl. Maps to source symbol `P_lacl`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
      }
    ]
  },
  "title": "Elowitz2000 - Synthetic Oscillatory Network Transcriptional Regulators Lab",
  "models": [
    {
      "path": "owned/models/physiology_cellml_elowitz_leibler_2000_elowitzleibler2000_model",
      "alias": "physiology_cellml_elowitz_leibler_2000_elowitzleibler2000_model",
      "parameters": {
        "model_path": "data/elowitz_leibler_2000.cellml",
        "integration_step": 0.01
      },
      "provenance": {
        "owned_path": "owned/models/physiology_cellml_elowitz_leibler_2000_elowitzleibler2000_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.physiology_cellml_elowitz_leibler_2000_elowitzleibler2000_model_state"
      ],
      "from": "physiology_cellml_elowitz_leibler_2000_elowitzleibler2000_model.state"
    },
    {
      "to": [
        "visualisation.physiology_cellml_elowitz_leibler_2000_elowitzleibler2000_model_summary"
      ],
      "from": "physiology_cellml_elowitz_leibler_2000_elowitzleibler2000_model.summary"
    },
    {
      "to": [
        "visualisation.physiology_cellml_elowitz_leibler_2000_elowitzleibler2000_model_trajectory"
      ],
      "from": "physiology_cellml_elowitz_leibler_2000_elowitzleibler2000_model.trajectory"
    },
    {
      "to": [
        "visualisation.physiology_cellml_elowitz_leibler_2000_elowitzleibler2000_model_variable_labels"
      ],
      "from": "physiology_cellml_elowitz_leibler_2000_elowitzleibler2000_model.variable_labels"
    }
  ],
  "runtime": {
    "duration": 0.01,
    "settle_steps": 1,
    "initial_inputs": {},
    "communication_step": 0.01
  },
  "description": "Source-faithful physiology lab for Elowitz, Leibler, 2000. Public controls and outputs are mapped to real source symbols for oscillatory physiology.",
  "schema_version": "2.0"
}

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