Chang2008 - ERK activation, hallucinogenic drugs mediated signalling through serotonin receptors Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_source_defined_pip2_state",
        "label": "Initial source-defined PIP2 state",
        "maps_to": "signaling_sbml_chang2008_erk_activation_hallucinogenic_drugs_me_model0975191032_model.initial_source_defined_pip2_state",
        "description": "Initial level of source-defined PIP2 state. Maps to SBML symbol `PIP2`; exposed as a traceable initial-condition perturbation."
      }
    ],
    "outputs": [
      {
        "name": "cpx_erk_pp_mkp_pp",
        "label": "Cpx ERK PP MKP PP",
        "maps_to": "signaling_sbml_chang2008_erk_activation_hallucinogenic_drugs_me_model0975191032_model.cpx_erk_pp_mkp_pp",
        "description": "Cpx ERK PP MKP PP. Maps to SBML symbol `cpxERK_PP_MKP_PP` and is emitted in native SBML units."
      },
      {
        "name": "cpx_erkp_mkp_pp",
        "label": "Cpx ERKP MKP PP",
        "maps_to": "signaling_sbml_chang2008_erk_activation_hallucinogenic_drugs_me_model0975191032_model.cpx_erkp_mkp_pp",
        "description": "Cpx ERKP MKP PP. Maps to SBML symbol `cpxERKP_MKP_PP` and is emitted in native SBML units."
      },
      {
        "name": "active_erk_mkp_phosphatase_complex",
        "label": "active ERK-MKP phosphatase complex",
        "maps_to": "signaling_sbml_chang2008_erk_activation_hallucinogenic_drugs_me_model0975191032_model.active_erk_mkp_phosphatase_complex",
        "description": "active ERK-MKP phosphatase complex. Maps to SBML symbol `cpxERKP_MKP_PPstar` and is emitted in native SBML units."
      },
      {
        "name": "state",
        "label": "Observable state",
        "maps_to": "signaling_sbml_chang2008_erk_activation_hallucinogenic_drugs_me_model0975191032_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation summary",
        "maps_to": "signaling_sbml_chang2008_erk_activation_hallucinogenic_drugs_me_model0975191032_model.summary"
      },
      {
        "name": "species_labels",
        "label": "Observable labels",
        "maps_to": "signaling_sbml_chang2008_erk_activation_hallucinogenic_drugs_me_model0975191032_model.species_labels"
      }
    ]
  },
  "tags": [
    "signaling",
    "systems",
    "systems-biology",
    "sbml",
    "faithful",
    "biomodels_ebi",
    "mapk",
    "ras-erk",
    "gpcr",
    "pharmacology"
  ],
  "title": "Chang2008 - ERK activation, hallucinogenic drugs mediated signalling through serotonin receptors Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "signaling_sbml_chang2008_erk_activation_hallucinogenic_drugs_me_model0975191032_model"
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.signaling_sbml_chang2008_erk_activation_hallucinogenic_drugs_me_model0975191032_model_state"
      ],
      "from": "signaling_sbml_chang2008_erk_activation_hallucinogenic_drugs_me_model0975191032_model.state"
    },
    {
      "to": [
        "visualisation.signaling_sbml_chang2008_erk_activation_hallucinogenic_drugs_me_model0975191032_model_summary"
      ],
      "from": "signaling_sbml_chang2008_erk_activation_hallucinogenic_drugs_me_model0975191032_model.summary"
    },
    {
      "to": [
        "visualisation.signaling_sbml_chang2008_erk_activation_hallucinogenic_drugs_me_model0975191032_model_species_labels"
      ],
      "from": "signaling_sbml_chang2008_erk_activation_hallucinogenic_drugs_me_model0975191032_model.species_labels"
    }
  ],
  "package": "chang2008-erk-activation-hallucinogenic-drugs-me",
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "version": "1.0.0",
  "description": "Clean Biosimulant lab for MAPK/ERK receptor signaling. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.",
  "schema_version": "2.0"
}