Varusai2018 - Dynamic modelling of the mTOR signalling network reveals complex emergent behaviours conferred by DEPTOR Lab
About lab
Clean Biosimulant lab for systems signaling model: Varusai2018 - Dynamic modelling of the mTOR signalling network reveals complex emergent behaviours conferred by DEPTOR. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.
Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagevarusai2018-dynamic-modelling-of-the-mtor-signalling-network-rev
Created2026-05-16
Updated2026-05-16
signalingsystemssystems-biologysbmlfaithfulbiomodels_ebimtorgpcrvisualisation
Manifest
{
"io": {
"inputs": [
{
"name": "initial_insulin_receptor",
"label": "Initial insulin receptor",
"maps_to": "signaling_sbml_varusai2018_dynamic_modelling_of_the_mtor_signal_biomd0000000823_model.initial_insulin_receptor",
"description": "Initial level of insulin receptor. Maps to SBML symbol `IR`; exposed as a traceable initial-condition perturbation."
}
],
"outputs": [
{
"name": "akt",
"label": "AKT",
"maps_to": "signaling_sbml_varusai2018_dynamic_modelling_of_the_mtor_signal_biomd0000000823_model.akt",
"description": "AKT. Maps to SBML symbol `Akt` and is emitted in native SBML units."
},
{
"name": "source_defined_pakt_state",
"label": "source-defined PAKT state",
"maps_to": "signaling_sbml_varusai2018_dynamic_modelling_of_the_mtor_signal_biomd0000000823_model.source_defined_pakt_state",
"description": "source-defined PAKT state. Maps to SBML symbol `pAkt` and is emitted in native SBML units."
},
{
"name": "source_defined_pir_state",
"label": "source-defined PIR state",
"maps_to": "signaling_sbml_varusai2018_dynamic_modelling_of_the_mtor_signal_biomd0000000823_model.source_defined_pir_state",
"description": "source-defined PIR state. Maps to SBML symbol `pIR` and is emitted in native SBML units."
},
{
"name": "state",
"label": "Observable state",
"maps_to": "signaling_sbml_varusai2018_dynamic_modelling_of_the_mtor_signal_biomd0000000823_model.state"
},
{
"name": "summary",
"label": "Simulation summary",
"maps_to": "signaling_sbml_varusai2018_dynamic_modelling_of_the_mtor_signal_biomd0000000823_model.summary"
},
{
"name": "species_labels",
"label": "Observable labels",
"maps_to": "signaling_sbml_varusai2018_dynamic_modelling_of_the_mtor_signal_biomd0000000823_model.species_labels"
}
]
},
"tags": [
"signaling",
"systems",
"systems-biology",
"sbml",
"faithful",
"biomodels_ebi",
"mtor",
"gpcr"
],
"title": "Varusai2018 - Dynamic modelling of the mTOR signalling network reveals complex emergent behaviours conferred by DEPTOR Lab",
"models": [
{
"path": "owned/models/signaling_sbml_varusai2018_dynamic_modelling_of_the_mtor_signal_biomd0000000823_model",
"alias": "signaling_sbml_varusai2018_dynamic_modelling_of_the_mtor_signal_biomd0000000823_model",
"provenance": {
"owned_path": "owned/models/signaling_sbml_varusai2018_dynamic_modelling_of_the_mtor_signal_biomd0000000823_model"
}
},
{
"path": "owned/models/visualisation",
"alias": "visualisation",
"provenance": {
"owned_path": "owned/models/visualisation"
}
}
],
"wiring": [
{
"to": [
"visualisation.signaling_sbml_varusai2018_dynamic_modelling_of_the_mtor_signal_biomd0000000823_model_state"
],
"from": "signaling_sbml_varusai2018_dynamic_modelling_of_the_mtor_signal_biomd0000000823_model.state"
},
{
"to": [
"visualisation.signaling_sbml_varusai2018_dynamic_modelling_of_the_mtor_signal_biomd0000000823_model_summary"
],
"from": "signaling_sbml_varusai2018_dynamic_modelling_of_the_mtor_signal_biomd0000000823_model.summary"
},
{
"to": [
"visualisation.signaling_sbml_varusai2018_dynamic_modelling_of_the_mtor_signal_biomd0000000823_model_species_labels"
],
"from": "signaling_sbml_varusai2018_dynamic_modelling_of_the_mtor_signal_biomd0000000823_model.species_labels"
}
],
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"description": "Clean Biosimulant lab for systems signaling model: Varusai2018 - Dynamic modelling of the mTOR signalling network reveals complex emergent behaviours conferred by DEPTOR. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.",
"schema_version": "2.0"
}Sign in to start your own run. Public-lab history stays visible here.
Select a run from History to view its results.