Makhlouf2020 - No treatment model of the role of CD4 T cells in tumor-immune interactions Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_tumor_cells",
        "label": "Initial Tumor Cells",
        "units": "native source value",
        "default": 10000000,
        "maps_to": "immunology_sbml_makhlouf2020_no_treatment_model_of_the_role_of_c_biomd0000001042_model.initial_tumor_cells",
        "description": "Initial Tumor Cells. Sets the initial value of bundled SBML species `Tumor_cells`."
      },
      {
        "name": "initial_cd8_t_cells",
        "label": "Initial CD8 T Cells",
        "units": "native source value",
        "default": 100,
        "maps_to": "immunology_sbml_makhlouf2020_no_treatment_model_of_the_role_of_c_biomd0000001042_model.initial_cd8_t_cells",
        "description": "Initial CD8 T Cells. Sets the initial value of bundled SBML species `CD8_T_cells`."
      },
      {
        "name": "initial_cd4_t_cells",
        "label": "Initial CD4 T Cells",
        "units": "native source value",
        "default": 1000000,
        "maps_to": "immunology_sbml_makhlouf2020_no_treatment_model_of_the_role_of_c_biomd0000001042_model.initial_cd4_t_cells",
        "description": "Initial CD4 T Cells. Sets the initial value of bundled SBML species `CD4_T_cells`."
      },
      {
        "name": "initial_interleukin_2",
        "label": "Initial Interleukin 2",
        "units": "native source value",
        "default": 100000,
        "maps_to": "immunology_sbml_makhlouf2020_no_treatment_model_of_the_role_of_c_biomd0000001042_model.initial_interleukin_2",
        "description": "Initial Interleukin 2. Sets the initial value of bundled SBML species `IL_2`."
      },
      {
        "name": "initial_natural_killer_cells",
        "label": "Initial Natural Killer Cells",
        "units": "native source value",
        "default": 1000,
        "maps_to": "immunology_sbml_makhlouf2020_no_treatment_model_of_the_role_of_c_biomd0000001042_model.initial_natural_killer_cells",
        "description": "Initial Natural Killer Cells. Sets the initial value of bundled SBML species `NK_cells`."
      },
      {
        "name": "tumour_death_rate",
        "label": "Tumour Death Rate",
        "units": "unit_3",
        "default": 6.41e-11,
        "maps_to": "immunology_sbml_makhlouf2020_no_treatment_model_of_the_role_of_c_biomd0000001042_model.tumour_death_rate",
        "description": "Tumour Death Rate. Sets bundled SBML parameter `c`."
      },
      {
        "name": "tumour_death_rate_2",
        "label": "Tumour Death Rate 2",
        "units": "unit_4",
        "default": 0.2,
        "maps_to": "immunology_sbml_makhlouf2020_no_treatment_model_of_the_role_of_c_biomd0000001042_model.tumour_death_rate_2",
        "description": "Tumour Death Rate 2. Sets bundled SBML parameter `c_1`."
      }
    ],
    "outputs": [
      {
        "name": "tumor_cells",
        "maps_to": "immunology_sbml_makhlouf2020_no_treatment_model_of_the_role_of_c_biomd0000001042_model.tumor_cells"
      },
      {
        "name": "cd8_t_cells",
        "maps_to": "immunology_sbml_makhlouf2020_no_treatment_model_of_the_role_of_c_biomd0000001042_model.cd8_t_cells"
      },
      {
        "name": "cd4_t_cells",
        "maps_to": "immunology_sbml_makhlouf2020_no_treatment_model_of_the_role_of_c_biomd0000001042_model.cd4_t_cells"
      },
      {
        "name": "interleukin_2",
        "maps_to": "immunology_sbml_makhlouf2020_no_treatment_model_of_the_role_of_c_biomd0000001042_model.interleukin_2"
      },
      {
        "name": "natural_killer_cells",
        "maps_to": "immunology_sbml_makhlouf2020_no_treatment_model_of_the_role_of_c_biomd0000001042_model.natural_killer_cells"
      },
      {
        "name": "state",
        "maps_to": "immunology_sbml_makhlouf2020_no_treatment_model_of_the_role_of_c_biomd0000001042_model.state"
      },
      {
        "name": "summary",
        "maps_to": "immunology_sbml_makhlouf2020_no_treatment_model_of_the_role_of_c_biomd0000001042_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "immunology_sbml_makhlouf2020_no_treatment_model_of_the_role_of_c_biomd0000001042_model.species_labels"
      }
    ]
  },
  "title": "Makhlouf2020 - No treatment model of the role of CD4 T cells in tumor-immune interactions Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "immunology_sbml_makhlouf2020_no_treatment_model_of_the_role_of_c_biomd0000001042_model"
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.immunology_sbml_makhlouf2020_no_treatment_model_of_the_role_of_c_biomd0000001042_model_state"
      ],
      "from": "immunology_sbml_makhlouf2020_no_treatment_model_of_the_role_of_c_biomd0000001042_model.state"
    },
    {
      "to": [
        "visualisation.immunology_sbml_makhlouf2020_no_treatment_model_of_the_role_of_c_biomd0000001042_model_summary"
      ],
      "from": "immunology_sbml_makhlouf2020_no_treatment_model_of_the_role_of_c_biomd0000001042_model.summary"
    },
    {
      "to": [
        "visualisation.immunology_sbml_makhlouf2020_no_treatment_model_of_the_role_of_c_biomd0000001042_model_species_labels"
      ],
      "from": "immunology_sbml_makhlouf2020_no_treatment_model_of_the_role_of_c_biomd0000001042_model.species_labels"
    }
  ],
  "package": "makhlouf2020-no-treatment-model-of-the-role-of",
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "version": "1.0.0",
  "description": "This ordinary differential equation model simulating the interactions between tumor and immune cells is detailed in the publication:Ahmed M. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
  "schema_version": "2.0"
}