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Kroll2000 - Martin Mathematical Temporal Effects Parathyroid Hormone Lab

About lab

Source-faithful physiology lab for Kroll, 2000. Public controls and outputs are mapped to real source symbols for bone and endocrine physiology.

Runtime

Duration0.01
Comms Step0.01
Settle Steps1

Runs

Total0
Completed0
Failed0

Metadata

Packagekroll2000-martin-mathematical-temporal-effects-parathyroid-hormo
Created2026-05-23
Updated2026-05-23
physiologycellmlphysiomefaithfulvisualisationother

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_pth",
        "label": "Initial Pth",
        "maps_to": "physiology_cellml_kroll_2000_kroll2000_model.initial_pth",
        "description": "Initial value for Pth. Maps to source symbol `P`. Units: dimensionless. Naming evidence: source metadata names `P` as `PTH`.",
        "accepted_units": [
          "dimensionless"
        ]
      },
      {
        "name": "initial_interleukin_6_concentration",
        "label": "Initial Interleukin 6 Concentration",
        "maps_to": "physiology_cellml_kroll_2000_kroll2000_model.initial_interleukin_6_concentration",
        "description": "Initial value for Interleukin 6 Concentration. Maps to source symbol `IL6`. Units: dimensionless. Naming evidence: source metadata names `IL6` as `interleukin-6 concentration`.",
        "accepted_units": [
          "dimensionless"
        ]
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Selected Source State",
        "maps_to": "physiology_cellml_kroll_2000_kroll2000_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation Summary",
        "maps_to": "physiology_cellml_kroll_2000_kroll2000_model.summary"
      },
      {
        "name": "trajectory",
        "label": "Source Trajectory",
        "maps_to": "physiology_cellml_kroll_2000_kroll2000_model.trajectory"
      },
      {
        "name": "variable_labels",
        "label": "Observable Labels",
        "maps_to": "physiology_cellml_kroll_2000_kroll2000_model.variable_labels"
      },
      {
        "name": "pth",
        "label": "Pth",
        "maps_to": "physiology_cellml_kroll_2000_kroll2000_model.pth",
        "description": "Pth. Maps to source symbol `P`. Units: dimensionless. Naming evidence: source metadata names `P` as `PTH`."
      },
      {
        "name": "interleukin_6_concentration",
        "label": "Interleukin 6 Concentration",
        "maps_to": "physiology_cellml_kroll_2000_kroll2000_model.interleukin_6_concentration",
        "description": "Interleukin 6 Concentration. Maps to source symbol `IL6`. Units: dimensionless. Naming evidence: source metadata names `IL6` as `interleukin-6 concentration`."
      },
      {
        "name": "number_of_osteoblasts",
        "label": "Number Of Osteoblasts",
        "maps_to": "physiology_cellml_kroll_2000_kroll2000_model.number_of_osteoblasts",
        "description": "Number Of Osteoblasts. Maps to source symbol `X`. Units: dimensionless. Naming evidence: source metadata names `X` as `number of osteoblasts`."
      },
      {
        "name": "number_of_osteoclasts",
        "label": "Number Of Osteoclasts",
        "maps_to": "physiology_cellml_kroll_2000_kroll2000_model.number_of_osteoclasts",
        "description": "Number Of Osteoclasts. Maps to source symbol `Z`. Units: dimensionless. Naming evidence: source metadata names `Z` as `number of osteoclasts`."
      },
      {
        "name": "number_of_preosteoblasts",
        "label": "Number Of Preosteoblasts",
        "maps_to": "physiology_cellml_kroll_2000_kroll2000_model.number_of_preosteoblasts",
        "description": "Number Of Preosteoblasts. Maps to source symbol `Y`. Units: dimensionless. Naming evidence: source metadata names `Y` as `number of preosteoblasts`."
      },
      {
        "name": "model_parameters_c",
        "label": "Model Parameters C",
        "maps_to": "physiology_cellml_kroll_2000_kroll2000_model.model_parameters_c",
        "description": "Model Parameters C. Maps to source symbol `C`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
      }
    ]
  },
  "title": "Kroll2000 - Martin Mathematical Temporal Effects Parathyroid Hormone Lab",
  "models": [
    {
      "path": "owned/models/physiology_cellml_kroll_2000_kroll2000_model",
      "alias": "physiology_cellml_kroll_2000_kroll2000_model",
      "parameters": {
        "model_path": "data/kroll_2000.cellml",
        "integration_step": 0.01
      },
      "provenance": {
        "owned_path": "owned/models/physiology_cellml_kroll_2000_kroll2000_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.physiology_cellml_kroll_2000_kroll2000_model_state"
      ],
      "from": "physiology_cellml_kroll_2000_kroll2000_model.state"
    },
    {
      "to": [
        "visualisation.physiology_cellml_kroll_2000_kroll2000_model_summary"
      ],
      "from": "physiology_cellml_kroll_2000_kroll2000_model.summary"
    },
    {
      "to": [
        "visualisation.physiology_cellml_kroll_2000_kroll2000_model_trajectory"
      ],
      "from": "physiology_cellml_kroll_2000_kroll2000_model.trajectory"
    },
    {
      "to": [
        "visualisation.physiology_cellml_kroll_2000_kroll2000_model_variable_labels"
      ],
      "from": "physiology_cellml_kroll_2000_kroll2000_model.variable_labels"
    }
  ],
  "runtime": {
    "duration": 0.01,
    "settle_steps": 1,
    "initial_inputs": {},
    "communication_step": 0.01
  },
  "description": "Source-faithful physiology lab for Kroll, 2000. Public controls and outputs are mapped to real source symbols for bone and endocrine physiology.",
  "schema_version": "2.0"
}

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