About lab
Heldt et al. (2002) lumped-parameter circulation (LPC) model tracking aortic pressure, mean arterial pressure, and aortic flow under orthostatic stress.
Runtime
Duration60
Comms Step1
Runs
Total6
Completed6
Failed0
Metadata
Packageheldt2002-lpc
Created2026-05-04
Updated2026-06-13
biomechanicscardiovascularlumped-parametersbmlbiomodels_ebifaithfulvisualisationheldt2002other
Manifest
{
"io": {
"inputs": [
{
"name": "heart_rate",
"maps_to": "heldt2002_orthostaticstress_lpc.heart_rate"
},
{
"name": "integration_step",
"maps_to": "heldt2002_orthostaticstress_lpc.integration_step"
},
{
"name": "peak_lv_elastance",
"maps_to": "heldt2002_orthostaticstress_lpc.peak_lv_elastance"
}
],
"outputs": [
{
"name": "cardiac_output",
"maps_to": "heldt2002_orthostaticstress_lpc.cardiac_output"
},
{
"name": "mean_arterial_pressure",
"maps_to": "heldt2002_orthostaticstress_lpc.mean_arterial_pressure"
},
{
"name": "state",
"maps_to": "heldt2002_orthostaticstress_lpc.state"
},
{
"name": "summary",
"maps_to": "heldt2002_orthostaticstress_lpc.summary"
}
]
},
"title": "Heldt2002 Orthostatic Stress - Lumped Parameter Circulation Lab",
"models": [
{
"path": "models/core",
"alias": "heldt2002_orthostaticstress_lpc",
"parameters": {
"model_path": "data/MODEL1006230113.xml",
"integration_step": 0.05
}
},
{
"path": "models/visualisation",
"alias": "visualisation"
}
],
"wiring": [
{
"to": [
"visualisation.heldt2002_orthostaticstress_lpc_cardiac_output"
],
"from": "heldt2002_orthostaticstress_lpc.cardiac_output"
},
{
"to": [
"visualisation.heldt2002_orthostaticstress_lpc_mean_arterial_pressure"
],
"from": "heldt2002_orthostaticstress_lpc.mean_arterial_pressure"
},
{
"to": [
"visualisation.heldt2002_orthostaticstress_lpc_state"
],
"from": "heldt2002_orthostaticstress_lpc.state"
},
{
"to": [
"visualisation.heldt2002_orthostaticstress_lpc_summary"
],
"from": "heldt2002_orthostaticstress_lpc.summary"
},
{
"to": [
"visualisation.heldt2002_orthostaticstress_lpc_visualisation_aux"
],
"from": "heldt2002_orthostaticstress_lpc.visualisation_aux"
}
],
"package": "heldt2002-lpc",
"runtime": {
"duration": 60,
"initial_inputs": {},
"communication_step": 1
},
"version": "1.0.0",
"description": "Heldt et al. (2002) lumped-parameter circulation (LPC) model tracking aortic pressure, mean arterial pressure, and aortic flow under orthostatic stress.",
"schema_version": "2.0"
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