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Nwabugwu2013 - A Tumor-Immune Mathematical Model of CD4+ T Helper Cell Lab

About lab

Its a mathematical model presenting the interaction between a growing tumor and immune system. Model involves tumor cells, dendritic cell, helper Tcells, regulatory Tcells, effector cells and certain.

Runtime

Duration10
Comms Step1

Runs

Total0
Completed0
Failed0

Metadata

Packagenwabugwu2013-a-tumor-immune-mathematical-model-of-cd4-t-helper-c
Created2026-05-15
Updated2026-05-15
immunologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_memtcell",
        "label": "Initial Memtcell",
        "units": "native source value",
        "default": 10000000,
        "maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.initial_memtcell",
        "description": "Initial Memtcell. Sets the initial value of bundled SBML species `M`."
      },
      {
        "name": "initial_memhelpertcells",
        "label": "Initial Memhelpertcells",
        "units": "native source value",
        "default": 6000000,
        "maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.initial_memhelpertcells",
        "description": "Initial Memhelpertcells. Sets the initial value of bundled SBML species `Mh`."
      },
      {
        "name": "initial_memeffectorcells",
        "label": "Initial Memeffectorcells",
        "units": "native source value",
        "default": 3000000,
        "maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.initial_memeffectorcells",
        "description": "Initial Memeffectorcells. Sets the initial value of bundled SBML species `Me`."
      },
      {
        "name": "initial_regmemtcell",
        "label": "Initial Regmemtcell",
        "units": "native source value",
        "default": 1000000,
        "maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.initial_regmemtcell",
        "description": "Initial Regmemtcell. Sets the initial value of bundled SBML species `Mr`."
      },
      {
        "name": "tumor_growth_rate",
        "label": "Tumor Growth Rate",
        "units": "unit_0",
        "default": 333,
        "maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.tumor_growth_rate",
        "description": "Tumor Growth Rate. Sets bundled SBML parameter `gamma`."
      },
      {
        "name": "tumor_cell_killing_rate",
        "label": "Tumor Cell Killing Rate",
        "units": "unit_1",
        "default": 1.2,
        "maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.tumor_cell_killing_rate",
        "description": "Tumor Cell Killing Rate. Sets bundled SBML parameter `k2`."
      },
      {
        "name": "tumor_cell_killing_rate_2",
        "label": "Tumor Cell Killing Rate 2",
        "units": "unit_1",
        "default": 11,
        "maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.tumor_cell_killing_rate_2",
        "description": "Tumor Cell Killing Rate 2. Sets bundled SBML parameter `k3`."
      }
    ],
    "outputs": [
      {
        "name": "memtcell",
        "maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.memtcell"
      },
      {
        "name": "memhelpertcells",
        "maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.memhelpertcells"
      },
      {
        "name": "memeffectorcells",
        "maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.memeffectorcells"
      },
      {
        "name": "regmemtcell",
        "maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.regmemtcell"
      },
      {
        "name": "source",
        "maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.source"
      },
      {
        "name": "state",
        "maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.state"
      },
      {
        "name": "summary",
        "maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.species_labels"
      }
    ]
  },
  "title": "Nwabugwu2013 - A Tumor-Immune Mathematical Model of CD4+ T Helper Cell Lab",
  "models": [
    {
      "path": "owned/models/immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model",
      "alias": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model",
      "provenance": {
        "owned_path": "owned/models/immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model_state"
      ],
      "from": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.state"
    },
    {
      "to": [
        "visualisation.immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model_summary"
      ],
      "from": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.summary"
    },
    {
      "to": [
        "visualisation.immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model_species_labels"
      ],
      "from": "immunology_sbml_nwabugwu2013_a_tumor_immune_mathematical_model_o_model2007090001_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "Its a mathematical model presenting the interaction between a growing tumor and immune system. Model involves tumor cells, dendritic cell, helper Tcells, regulatory Tcells, effector cells and certain.",
  "schema_version": "2.0"
}

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