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Terkildsen2008 - Calcium Dynamics Terkildsennied Lab

About lab

Source-faithful physiology lab for Terkildsen, Niederer, Crampin, Hunter, Smith, 2008. Public controls and outputs are mapped to real source symbols for electrophysiology.

Runtime

Duration0.01
Comms Step0.01
Settle Steps1

Runs

Total0
Completed0
Failed0

Metadata

Packageterkildsen2008-calcium-dynamics-terkildsennied-lab
Created2026-05-23
Updated2026-05-23
physiologycellmlphysiomefaithfulvisualisationother

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_intracellular_calcium",
        "label": "Initial Intracellular Calcium",
        "maps_to": "physiology_cellml_terkildsen_niederer_crampin_hunter_smith_2008_terkildsenniederercrampinhuntersmith2008_model.initial_intracellular_calcium",
        "description": "Initial value for Intracellular Calcium. Maps to source symbol `Ca_i`. Units: mM. Naming evidence: source symbol, component, or units provide a direct public name.",
        "accepted_units": [
          "mM"
        ]
      },
      {
        "name": "initial_ca_sr",
        "label": "Initial Ca Sr",
        "maps_to": "physiology_cellml_terkildsen_niederer_crampin_hunter_smith_2008_terkildsenniederercrampinhuntersmith2008_model.initial_ca_sr",
        "description": "Initial value for Ca Sr. Maps to source symbol `Ca_SR`. Units: mM. Naming evidence: source symbol, component, or units provide a direct public name.",
        "accepted_units": [
          "mM"
        ]
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Selected Source State",
        "maps_to": "physiology_cellml_terkildsen_niederer_crampin_hunter_smith_2008_terkildsenniederercrampinhuntersmith2008_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation Summary",
        "maps_to": "physiology_cellml_terkildsen_niederer_crampin_hunter_smith_2008_terkildsenniederercrampinhuntersmith2008_model.summary"
      },
      {
        "name": "trajectory",
        "label": "Source Trajectory",
        "maps_to": "physiology_cellml_terkildsen_niederer_crampin_hunter_smith_2008_terkildsenniederercrampinhuntersmith2008_model.trajectory"
      },
      {
        "name": "variable_labels",
        "label": "Observable Labels",
        "maps_to": "physiology_cellml_terkildsen_niederer_crampin_hunter_smith_2008_terkildsenniederercrampinhuntersmith2008_model.variable_labels"
      },
      {
        "name": "membrane_voltage",
        "label": "Membrane Voltage",
        "maps_to": "physiology_cellml_terkildsen_niederer_crampin_hunter_smith_2008_terkildsenniederercrampinhuntersmith2008_model.membrane_voltage",
        "description": "Membrane Voltage. Maps to source symbol `V`. Units: mV. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "calcium_conductance_g_ca_b",
        "label": "Calcium Conductance G Ca B",
        "maps_to": "physiology_cellml_terkildsen_niederer_crampin_hunter_smith_2008_terkildsenniederercrampinhuntersmith2008_model.calcium_conductance_g_ca_b",
        "description": "Calcium Conductance G Ca B. Maps to source symbol `g_CaB`. Units: mM_per_mV_ms. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "calcium_current",
        "label": "Calcium Current",
        "maps_to": "physiology_cellml_terkildsen_niederer_crampin_hunter_smith_2008_terkildsenniederercrampinhuntersmith2008_model.calcium_current",
        "description": "Calcium Current. Maps to source symbol `I_pCa`. Units: mM_per_ms. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "calcium_current_i_ca_b",
        "label": "Calcium Current I Ca B",
        "maps_to": "physiology_cellml_terkildsen_niederer_crampin_hunter_smith_2008_terkildsenniederercrampinhuntersmith2008_model.calcium_current_i_ca_b",
        "description": "Calcium Current I Ca B. Maps to source symbol `I_CaB`. Units: mM_per_ms. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "calcium_reversal_potential",
        "label": "Calcium Reversal Potential",
        "maps_to": "physiology_cellml_terkildsen_niederer_crampin_hunter_smith_2008_terkildsenniederercrampinhuntersmith2008_model.calcium_reversal_potential",
        "description": "Calcium Reversal Potential. Maps to source symbol `E_Ca`. Units: mV. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "intracellular_calcium",
        "label": "Intracellular Calcium",
        "maps_to": "physiology_cellml_terkildsen_niederer_crampin_hunter_smith_2008_terkildsenniederercrampinhuntersmith2008_model.intracellular_calcium",
        "description": "Intracellular Calcium. Maps to source symbol `Ca_i`. Units: mM. Naming evidence: source symbol, component, or units provide a direct public name."
      }
    ]
  },
  "title": "Terkildsen2008 - Calcium Dynamics Terkildsennied Lab",
  "models": [
    {
      "path": "owned/models/physiology_cellml_terkildsen_niederer_crampin_hunter_smith_2008_terkildsenniederercrampinhuntersmith2008_model",
      "alias": "physiology_cellml_terkildsen_niederer_crampin_hunter_smith_2008_terkildsenniederercrampinhuntersmith2008_model",
      "parameters": {
        "model_path": "data/Hinch_et_al_2004.cellml",
        "integration_step": 0.01
      },
      "provenance": {
        "owned_path": "owned/models/physiology_cellml_terkildsen_niederer_crampin_hunter_smith_2008_terkildsenniederercrampinhuntersmith2008_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.physiology_cellml_terkildsen_niederer_crampin_hunter_smith_2008_terkildsenniederercrampinhuntersmith2008_model_state"
      ],
      "from": "physiology_cellml_terkildsen_niederer_crampin_hunter_smith_2008_terkildsenniederercrampinhuntersmith2008_model.state"
    },
    {
      "to": [
        "visualisation.physiology_cellml_terkildsen_niederer_crampin_hunter_smith_2008_terkildsenniederercrampinhuntersmith2008_model_summary"
      ],
      "from": "physiology_cellml_terkildsen_niederer_crampin_hunter_smith_2008_terkildsenniederercrampinhuntersmith2008_model.summary"
    },
    {
      "to": [
        "visualisation.physiology_cellml_terkildsen_niederer_crampin_hunter_smith_2008_terkildsenniederercrampinhuntersmith2008_model_trajectory"
      ],
      "from": "physiology_cellml_terkildsen_niederer_crampin_hunter_smith_2008_terkildsenniederercrampinhuntersmith2008_model.trajectory"
    },
    {
      "to": [
        "visualisation.physiology_cellml_terkildsen_niederer_crampin_hunter_smith_2008_terkildsenniederercrampinhuntersmith2008_model_variable_labels"
      ],
      "from": "physiology_cellml_terkildsen_niederer_crampin_hunter_smith_2008_terkildsenniederercrampinhuntersmith2008_model.variable_labels"
    }
  ],
  "runtime": {
    "duration": 0.01,
    "settle_steps": 1,
    "initial_inputs": {},
    "communication_step": 0.01
  },
  "description": "Source-faithful physiology lab for Terkildsen, Niederer, Crampin, Hunter, Smith, 2008. Public controls and outputs are mapped to real source symbols for electrophysiology.",
  "schema_version": "2.0"
}

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