Bianca2012 - Mathematical modeling of the immune system recognition to mammary carcinoma antigen Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_unresolved_tumor_observable_1",
        "label": "Initial Unresolved Tumor Observable 1",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_bianca2012_mathematical_modeling_of_the_immune_s_model1907260002_model.initial_unresolved_tumor_observable_1",
        "description": "Initial Unresolved Tumor Observable 1. Sets the initial value of bundled SBML species `VC`."
      },
      {
        "name": "initial_unresolved_tumor_observable_2",
        "label": "Initial Unresolved Tumor Observable 2",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_bianca2012_mathematical_modeling_of_the_immune_s_model1907260002_model.initial_unresolved_tumor_observable_2",
        "description": "Initial Unresolved Tumor Observable 2. Sets the initial value of bundled SBML species `TAA`."
      },
      {
        "name": "initial_unresolved_tumor_observable_3",
        "label": "Initial Unresolved Tumor Observable 3",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_bianca2012_mathematical_modeling_of_the_immune_s_model1907260002_model.initial_unresolved_tumor_observable_3",
        "description": "Initial Unresolved Tumor Observable 3. Sets the initial value of bundled SBML species `B`."
      },
      {
        "name": "initial_unresolved_tumor_observable_4",
        "label": "Initial Unresolved Tumor Observable 4",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_bianca2012_mathematical_modeling_of_the_immune_s_model1907260002_model.initial_unresolved_tumor_observable_4",
        "description": "Initial Unresolved Tumor Observable 4. Sets the initial value of bundled SBML species `TH`."
      },
      {
        "name": "initial_interleukin_12",
        "label": "Initial Interleukin 12",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_bianca2012_mathematical_modeling_of_the_immune_s_model1907260002_model.initial_interleukin_12",
        "description": "Initial Interleukin 12. Sets the initial value of bundled SBML species `IL12`."
      },
      {
        "name": "taa_release_vc_rate",
        "label": "Taa Release Vc Rate",
        "units": "native source value",
        "default": 3,
        "maps_to": "immunology_sbml_bianca2012_mathematical_modeling_of_the_immune_s_model1907260002_model.taa_release_vc_rate",
        "description": "Taa Release Vc Rate. Sets bundled SBML parameter `gamma_21`."
      },
      {
        "name": "taa_release_cc_rate",
        "label": "Taa Release Cc Rate",
        "units": "native source value",
        "default": 3,
        "maps_to": "immunology_sbml_bianca2012_mathematical_modeling_of_the_immune_s_model1907260002_model.taa_release_cc_rate",
        "description": "Taa Release Cc Rate. Sets bundled SBML parameter `gamma_28`."
      },
      {
        "name": "b_death_rate",
        "label": "B Death Rate",
        "units": "native source value",
        "default": 0.693147,
        "maps_to": "immunology_sbml_bianca2012_mathematical_modeling_of_the_immune_s_model1907260002_model.b_death_rate",
        "description": "B Death Rate. Sets bundled SBML parameter `mu_3`."
      },
      {
        "name": "th_death_rate",
        "label": "Th Death Rate",
        "units": "native source value",
        "default": 0.693147,
        "maps_to": "immunology_sbml_bianca2012_mathematical_modeling_of_the_immune_s_model1907260002_model.th_death_rate",
        "description": "Th Death Rate. Sets bundled SBML parameter `mu_4`."
      },
      {
        "name": "interleukin_12_release_vc_rate",
        "label": "Interleukin 12 Release Vc Rate",
        "units": "native source value",
        "default": 10,
        "maps_to": "immunology_sbml_bianca2012_mathematical_modeling_of_the_immune_s_model1907260002_model.interleukin_12_release_vc_rate",
        "description": "Interleukin 12 Release Vc Rate. Sets bundled SBML parameter `gamma_51`."
      }
    ],
    "outputs": [
      {
        "name": "unresolved_tumor_observable_1",
        "maps_to": "immunology_sbml_bianca2012_mathematical_modeling_of_the_immune_s_model1907260002_model.unresolved_tumor_observable_1"
      },
      {
        "name": "unresolved_tumor_observable_2",
        "maps_to": "immunology_sbml_bianca2012_mathematical_modeling_of_the_immune_s_model1907260002_model.unresolved_tumor_observable_2"
      },
      {
        "name": "unresolved_tumor_observable_3",
        "maps_to": "immunology_sbml_bianca2012_mathematical_modeling_of_the_immune_s_model1907260002_model.unresolved_tumor_observable_3"
      },
      {
        "name": "unresolved_tumor_observable_4",
        "maps_to": "immunology_sbml_bianca2012_mathematical_modeling_of_the_immune_s_model1907260002_model.unresolved_tumor_observable_4"
      },
      {
        "name": "interleukin_12",
        "maps_to": "immunology_sbml_bianca2012_mathematical_modeling_of_the_immune_s_model1907260002_model.interleukin_12"
      },
      {
        "name": "state",
        "maps_to": "immunology_sbml_bianca2012_mathematical_modeling_of_the_immune_s_model1907260002_model.state"
      },
      {
        "name": "summary",
        "maps_to": "immunology_sbml_bianca2012_mathematical_modeling_of_the_immune_s_model1907260002_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "immunology_sbml_bianca2012_mathematical_modeling_of_the_immune_s_model1907260002_model.species_labels"
      }
    ]
  },
  "title": "Bianca2012 - Mathematical modeling of the immune system recognition to mammary carcinoma antigen Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "immunology_sbml_bianca2012_mathematical_modeling_of_the_immune_s_model1907260002_model"
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.immunology_sbml_bianca2012_mathematical_modeling_of_the_immune_s_model1907260002_model_state"
      ],
      "from": "immunology_sbml_bianca2012_mathematical_modeling_of_the_immune_s_model1907260002_model.state"
    },
    {
      "to": [
        "visualisation.immunology_sbml_bianca2012_mathematical_modeling_of_the_immune_s_model1907260002_model_summary"
      ],
      "from": "immunology_sbml_bianca2012_mathematical_modeling_of_the_immune_s_model1907260002_model.summary"
    },
    {
      "to": [
        "visualisation.immunology_sbml_bianca2012_mathematical_modeling_of_the_immune_s_model1907260002_model_species_labels"
      ],
      "from": "immunology_sbml_bianca2012_mathematical_modeling_of_the_immune_s_model1907260002_model.species_labels"
    }
  ],
  "package": "bianca2012-mathematical-modeling-of-the-immune-system-r-ba9cfb92",
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "version": "1.0.1",
  "description": "This model describes the humoral and cellular response of the immune system to a tumor associate antigen and the recognition process between B cells, T cells and antigen presenting cells. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
  "schema_version": "2.0"
}