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Vempati2007 Mmp9 Regulation Lab

About lab

This is the model described in the article: A biochemical model of matrix metalloproteinase 9 activation and inhibition. It can be used to explore systemsbiology vempati2007 mmp9 regulation model7888000034 dynamics and compare simulation behavior across conditions.

Runtime

Duration1
Comms Step0.1

Runs

Total0
Completed0
Failed0

Metadata

Packagevempati2007-mmp9-regulation-lab
Created2026-05-17
Updated2026-05-17
systemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_tr_pm9_t1_m3",
        "label": "Initial Tr PM9 T1 M3",
        "maps_to": "systemsbiology_sbml_vempati2007_mmp9_regulation_model7888000034_model.initial_tr_pm9_t1_m3",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Tr_pM9_T1_M3`."
      },
      {
        "name": "initial_tr_pm9_t1",
        "label": "Initial Tr PM9 T1",
        "maps_to": "systemsbiology_sbml_vempati2007_mmp9_regulation_model7888000034_model.initial_tr_pm9_t1",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Tr_pM9_T1`."
      },
      {
        "name": "initial_tr_pm9",
        "label": "Initial Tr PM9",
        "maps_to": "systemsbiology_sbml_vempati2007_mmp9_regulation_model7888000034_model.initial_tr_pm9",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Tr_pM9`."
      },
      {
        "name": "initial_model_state_tr",
        "label": "Initial Model State Tr",
        "maps_to": "systemsbiology_sbml_vempati2007_mmp9_regulation_model7888000034_model.initial_model_state_tr",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Tr`."
      },
      {
        "name": "initial_model_state_t1",
        "label": "Initial Model State T1",
        "maps_to": "systemsbiology_sbml_vempati2007_mmp9_regulation_model7888000034_model.initial_model_state_t1",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `T1`."
      },
      {
        "name": "initial_pm9_t1_m3",
        "label": "Initial PM9 T1 M3",
        "maps_to": "systemsbiology_sbml_vempati2007_mmp9_regulation_model7888000034_model.initial_pm9_t1_m3",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `pM9_T1_M3`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_vempati2007_mmp9_regulation_model7888000034_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_vempati2007_mmp9_regulation_model7888000034_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_vempati2007_mmp9_regulation_model7888000034_model.species_labels"
      },
      {
        "name": "tr_pm9_t1_m3",
        "maps_to": "systemsbiology_sbml_vempati2007_mmp9_regulation_model7888000034_model.tr_pm9_t1_m3"
      },
      {
        "name": "tr_pm9_t1",
        "maps_to": "systemsbiology_sbml_vempati2007_mmp9_regulation_model7888000034_model.tr_pm9_t1"
      },
      {
        "name": "tr_pm9",
        "maps_to": "systemsbiology_sbml_vempati2007_mmp9_regulation_model7888000034_model.tr_pm9"
      },
      {
        "name": "model_state_tr",
        "maps_to": "systemsbiology_sbml_vempati2007_mmp9_regulation_model7888000034_model.model_state_tr"
      },
      {
        "name": "model_state_t1",
        "maps_to": "systemsbiology_sbml_vempati2007_mmp9_regulation_model7888000034_model.model_state_t1"
      },
      {
        "name": "pm9_t1_m3",
        "maps_to": "systemsbiology_sbml_vempati2007_mmp9_regulation_model7888000034_model.pm9_t1_m3"
      }
    ]
  },
  "tags": [
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Vempati2007 Mmp9 Regulation Lab",
  "models": [
    {
      "path": "owned/models/systemsbiology_sbml_vempati2007_mmp9_regulation_model7888000034_model",
      "alias": "systemsbiology_sbml_vempati2007_mmp9_regulation_model7888000034_model",
      "provenance": {
        "owned_path": "owned/models/systemsbiology_sbml_vempati2007_mmp9_regulation_model7888000034_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.systemsbiology_sbml_vempati2007_mmp9_regulation_model7888000034_model_state"
      ],
      "from": "systemsbiology_sbml_vempati2007_mmp9_regulation_model7888000034_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_vempati2007_mmp9_regulation_model7888000034_model_summary"
      ],
      "from": "systemsbiology_sbml_vempati2007_mmp9_regulation_model7888000034_model.summary"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_vempati2007_mmp9_regulation_model7888000034_model_species_labels"
      ],
      "from": "systemsbiology_sbml_vempati2007_mmp9_regulation_model7888000034_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "This is the model described in the article: A biochemical model of matrix metalloproteinase 9 activation and inhibition. It can be used to explore systemsbiology vempati2007 mmp9 regulation model7888000034 dynamics and compare simulation behavior across conditions.",
  "schema_version": "2.0"
}

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