About lab
This model is from the article: On the encoding and decoding of calcium signals in hepatocytes Ann Zahle Larsen, Lars Folke Olsen and Ursula Kummera Biophysical Chemistry Volume 107, Issue 1, 1 Januar. It can be used to explore systemsbiology larsen2004 calciumspiking BioModels0000000330 dynamics and compare simulation behavior across conditions.
Runtime
Duration1
Comms Step0.1
Runs
Total0
Completed0
Failed0
Metadata
Packagelarsen2004-calciumspiking-lab
Created2026-05-17
Updated2026-05-17
physiologysystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisation
Manifest
{
"io": {
"inputs": [
{
"name": "initial_calcium_er",
"label": "Initial Calcium Er",
"maps_to": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.initial_calcium_er",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Ca_ER`."
},
{
"name": "initial_g_alpha",
"label": "Initial G Alpha",
"maps_to": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.initial_g_alpha",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `G_alpha`."
},
{
"name": "initial_calcium_cyt",
"label": "Initial Calcium Cyt",
"maps_to": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.initial_calcium_cyt",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Ca_cyt`."
},
{
"name": "initial_calcium_mit",
"label": "Initial Calcium Mit",
"maps_to": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.initial_calcium_mit",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Ca_mit`."
},
{
"name": "initial_model_state_plc",
"label": "Initial Model State Plc",
"maps_to": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.initial_model_state_plc",
"description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `PLC`."
}
],
"outputs": [
{
"name": "state",
"maps_to": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.state"
},
{
"name": "summary",
"maps_to": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.summary"
},
{
"name": "species_labels",
"maps_to": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.species_labels"
},
{
"name": "calcium_er",
"maps_to": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.calcium_er"
},
{
"name": "g_alpha",
"maps_to": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.g_alpha"
},
{
"name": "calcium_cyt",
"maps_to": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.calcium_cyt"
},
{
"name": "calcium_mit",
"maps_to": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.calcium_mit"
},
{
"name": "plc",
"maps_to": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.plc"
}
]
},
"tags": [
"physiology",
"systemsbiology",
"sbml",
"biomodels_ebi",
"faithful",
"curated"
],
"title": "Larsen2004 Calciumspiking Lab",
"models": [
{
"path": "owned/models/systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model",
"alias": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model",
"provenance": {
"owned_path": "owned/models/systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model"
}
},
{
"path": "owned/models/visualisation",
"alias": "visualisation",
"provenance": {
"owned_path": "owned/models/visualisation"
}
}
],
"wiring": [
{
"to": [
"visualisation.systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model_state"
],
"from": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.state"
},
{
"to": [
"visualisation.systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model_summary"
],
"from": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.summary"
},
{
"to": [
"visualisation.systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model_species_labels"
],
"from": "systemsbiology_sbml_larsen2004_calciumspiking_biomd0000000330_model.species_labels"
}
],
"runtime": {
"duration": 1,
"initial_inputs": {},
"communication_step": 0.1
},
"description": "This model is from the article: On the encoding and decoding of calcium signals in hepatocytes Ann Zahle Larsen, Lars Folke Olsen and Ursula Kummera Biophysical Chemistry Volume 107, Issue 1, 1 Januar. It can be used to explore systemsbiology larsen2004 calciumspiking BioModels0000000330 dynamics and compare simulation behavior across conditions.",
"schema_version": "2.0"
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