Zi2007 Tgfbeta Signaling Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_t1_r_cave",
        "label": "Initial T1 R Cave",
        "maps_to": "systemsbiology_sbml_zi2007_tgfbeta_signaling_biomd0000000163_model.initial_t1_r_cave",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `T1R_Cave`."
      },
      {
        "name": "initial_t1_r_ee",
        "label": "Initial T1 R Ee",
        "maps_to": "systemsbiology_sbml_zi2007_tgfbeta_signaling_biomd0000000163_model.initial_t1_r_ee",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `T1R_EE`."
      },
      {
        "name": "initial_t2_r_cave",
        "label": "Initial T2 R Cave",
        "maps_to": "systemsbiology_sbml_zi2007_tgfbeta_signaling_biomd0000000163_model.initial_t2_r_cave",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `T2R_Cave`."
      },
      {
        "name": "initial_t2_r_ee",
        "label": "Initial T2 R Ee",
        "maps_to": "systemsbiology_sbml_zi2007_tgfbeta_signaling_biomd0000000163_model.initial_t2_r_ee",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `T2R_EE`."
      },
      {
        "name": "initial_t1_r_surf",
        "label": "Initial T1 R Surf",
        "maps_to": "systemsbiology_sbml_zi2007_tgfbeta_signaling_biomd0000000163_model.initial_t1_r_surf",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `T1R_Surf`."
      },
      {
        "name": "initial_t2_r_surf",
        "label": "Initial T2 R Surf",
        "maps_to": "systemsbiology_sbml_zi2007_tgfbeta_signaling_biomd0000000163_model.initial_t2_r_surf",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `T2R_Surf`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_zi2007_tgfbeta_signaling_biomd0000000163_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_zi2007_tgfbeta_signaling_biomd0000000163_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_zi2007_tgfbeta_signaling_biomd0000000163_model.species_labels"
      },
      {
        "name": "t1_r_cave",
        "maps_to": "systemsbiology_sbml_zi2007_tgfbeta_signaling_biomd0000000163_model.t1_r_cave"
      },
      {
        "name": "t1_r_ee",
        "maps_to": "systemsbiology_sbml_zi2007_tgfbeta_signaling_biomd0000000163_model.t1_r_ee"
      },
      {
        "name": "t2_r_cave",
        "maps_to": "systemsbiology_sbml_zi2007_tgfbeta_signaling_biomd0000000163_model.t2_r_cave"
      },
      {
        "name": "t2_r_ee",
        "maps_to": "systemsbiology_sbml_zi2007_tgfbeta_signaling_biomd0000000163_model.t2_r_ee"
      },
      {
        "name": "t1_r_surf",
        "maps_to": "systemsbiology_sbml_zi2007_tgfbeta_signaling_biomd0000000163_model.t1_r_surf"
      },
      {
        "name": "t2_r_surf",
        "maps_to": "systemsbiology_sbml_zi2007_tgfbeta_signaling_biomd0000000163_model.t2_r_surf"
      }
    ]
  },
  "tags": [
    "signaling",
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Zi2007 Tgfbeta Signaling Lab",
  "models": [
    {
      "path": "owned/models/systemsbiology_sbml_zi2007_tgfbeta_signaling_biomd0000000163_model",
      "alias": "systemsbiology_sbml_zi2007_tgfbeta_signaling_biomd0000000163_model",
      "provenance": {
        "owned_path": "owned/models/systemsbiology_sbml_zi2007_tgfbeta_signaling_biomd0000000163_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.systemsbiology_sbml_zi2007_tgfbeta_signaling_biomd0000000163_model_state"
      ],
      "from": "systemsbiology_sbml_zi2007_tgfbeta_signaling_biomd0000000163_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_zi2007_tgfbeta_signaling_biomd0000000163_model_summary"
      ],
      "from": "systemsbiology_sbml_zi2007_tgfbeta_signaling_biomd0000000163_model.summary"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_zi2007_tgfbeta_signaling_biomd0000000163_model_species_labels"
      ],
      "from": "systemsbiology_sbml_zi2007_tgfbeta_signaling_biomd0000000163_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "The model reproduces the time profiles of Total Smad2 in the nucleus as well as the cytoplasm as depicted in 2D and also the other time profiles as depicted in Fig 2. It can be used to explore systemsbiology zi2007 tgfbeta signaling BioModels0000000163 dynamics and compare simulation behavior across conditions.",
  "schema_version": "2.0"
}