HeberleRazquinNavas2019 - The PI3K and MAPK/p38 pathways control stress granuleassembly in a hierarchical manner model 3 Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_akt_p_s473_obs",
        "label": "Initial AKT P S473 Obs",
        "maps_to": "signaling_sbml_heberlerazquinnavas2019_the_pi3k_and_mapk_p38_pa_biomd0000000907_model.initial_akt_p_s473_obs",
        "description": "Initial level of AKT P S473 Obs. Maps to SBML symbol `Akt_pS473_obs`; exposed as a traceable initial-condition perturbation."
      },
      {
        "name": "initial_akt_p_t308_obs",
        "label": "Initial AKT P T308 Obs",
        "maps_to": "signaling_sbml_heberlerazquinnavas2019_the_pi3k_and_mapk_p38_pa_biomd0000000907_model.initial_akt_p_t308_obs",
        "description": "Initial level of AKT P T308 Obs. Maps to SBML symbol `Akt_pT308_obs`; exposed as a traceable initial-condition perturbation."
      },
      {
        "name": "initial_four_ebp1_p_t37_46_obs",
        "label": "Initial Four EBP1 P T37 46 Obs",
        "maps_to": "signaling_sbml_heberlerazquinnavas2019_the_pi3k_and_mapk_p38_pa_biomd0000000907_model.initial_four_ebp1_p_t37_46_obs",
        "description": "Initial level of Four EBP1 P T37 46 Obs. Maps to SBML symbol `fourEBP1_pT37_46_obs`; exposed as a traceable initial-condition perturbation."
      }
    ],
    "outputs": [
      {
        "name": "akt_p_t308_obs",
        "label": "AKT P T308 Obs",
        "maps_to": "signaling_sbml_heberlerazquinnavas2019_the_pi3k_and_mapk_p38_pa_biomd0000000907_model.akt_p_t308_obs",
        "description": "AKT P T308 Obs. Maps to SBML symbol `Akt_pT308_obs` and is emitted in native SBML units."
      },
      {
        "name": "akt_p_s473_obs",
        "label": "AKT P S473 Obs",
        "maps_to": "signaling_sbml_heberlerazquinnavas2019_the_pi3k_and_mapk_p38_pa_biomd0000000907_model.akt_p_s473_obs",
        "description": "AKT P S473 Obs. Maps to SBML symbol `Akt_pS473_obs` and is emitted in native SBML units."
      },
      {
        "name": "pras40_p_t246_obs",
        "label": "PRAS40 P T246 Obs",
        "maps_to": "signaling_sbml_heberlerazquinnavas2019_the_pi3k_and_mapk_p38_pa_biomd0000000907_model.pras40_p_t246_obs",
        "description": "PRAS40 P T246 Obs. Maps to SBML symbol `PRAS40_pT246_obs` and is emitted in native SBML units."
      },
      {
        "name": "state",
        "label": "Observable state",
        "maps_to": "signaling_sbml_heberlerazquinnavas2019_the_pi3k_and_mapk_p38_pa_biomd0000000907_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation summary",
        "maps_to": "signaling_sbml_heberlerazquinnavas2019_the_pi3k_and_mapk_p38_pa_biomd0000000907_model.summary"
      },
      {
        "name": "species_labels",
        "label": "Observable labels",
        "maps_to": "signaling_sbml_heberlerazquinnavas2019_the_pi3k_and_mapk_p38_pa_biomd0000000907_model.species_labels"
      }
    ]
  },
  "tags": [
    "signaling",
    "systems",
    "systems-biology",
    "sbml",
    "faithful",
    "biomodels_ebi",
    "mapk",
    "pi3k-akt",
    "stress-response"
  ],
  "title": "HeberleRazquinNavas2019 - The PI3K and MAPK/p38 pathways control stress granuleassembly in a hierarchical manner model 3 Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "signaling_sbml_heberlerazquinnavas2019_the_pi3k_and_mapk_p38_pa_biomd0000000907_model"
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.signaling_sbml_heberlerazquinnavas2019_the_pi3k_and_mapk_p38_pa_biomd0000000907_model_state"
      ],
      "from": "signaling_sbml_heberlerazquinnavas2019_the_pi3k_and_mapk_p38_pa_biomd0000000907_model.state"
    },
    {
      "to": [
        "visualisation.signaling_sbml_heberlerazquinnavas2019_the_pi3k_and_mapk_p38_pa_biomd0000000907_model_summary"
      ],
      "from": "signaling_sbml_heberlerazquinnavas2019_the_pi3k_and_mapk_p38_pa_biomd0000000907_model.summary"
    },
    {
      "to": [
        "visualisation.signaling_sbml_heberlerazquinnavas2019_the_pi3k_and_mapk_p38_pa_biomd0000000907_model_species_labels"
      ],
      "from": "signaling_sbml_heberlerazquinnavas2019_the_pi3k_and_mapk_p38_pa_biomd0000000907_model.species_labels"
    }
  ],
  "package": "heberlerazquinnavas2019-the-pi3k-and-mapk-p38-pa",
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "version": "1.0.0",
  "description": "Clean Biosimulant lab for MAPK/ERK receptor signaling. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.",
  "schema_version": "2.0"
}