Smith2010 - Response of FOXO Transcription Factors to Post-Translational Modifications (with acetylation pathway) Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_cytoplasm_foxo1_tot",
        "label": "Initial Cytoplasm Foxo1 Tot",
        "maps_to": "signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000706_model.initial_cytoplasm_foxo1_tot",
        "description": "Initial level of Cytoplasm Foxo1 Tot. Maps to SBML symbol `cytoplasm_Foxo1_tot`; exposed as a traceable initial-condition perturbation."
      },
      {
        "name": "initial_dnabound_foxo1_tot",
        "label": "Initial Dnabound Foxo1 Tot",
        "maps_to": "signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000706_model.initial_dnabound_foxo1_tot",
        "description": "Initial level of Dnabound Foxo1 Tot. Maps to SBML symbol `dnabound_Foxo1_tot`; exposed as a traceable initial-condition perturbation."
      },
      {
        "name": "initial_foxo1_acetylated_tot",
        "label": "Initial Foxo1 Acetylated Tot",
        "maps_to": "signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000706_model.initial_foxo1_acetylated_tot",
        "description": "Initial level of Foxo1 Acetylated Tot. Maps to SBML symbol `Foxo1_Ac1_tot`; exposed as a traceable initial-condition perturbation."
      }
    ],
    "outputs": [
      {
        "name": "cytoplasm_foxo1_unphosphorylated_unacetylated_notpolyubiquitinated",
        "label": "Cytoplasm Foxo1 Unphosphorylated Unacetylated Notpolyubiquitinated",
        "maps_to": "signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000706_model.cytoplasm_foxo1_unphosphorylated_unacetylated_notpolyubiquitinated",
        "description": "Cytoplasm Foxo1 Unphosphorylated Unacetylated Notpolyubiquitinated. Maps to SBML symbol `cytoplasm_Foxo1_Pa0_Ac0_pUb0` and is emitted in native SBML units."
      },
      {
        "name": "nucleus_foxo1_unphosphorylated_unacetylated_notpolyubiquitinated",
        "label": "Nucleus Foxo1 Unphosphorylated Unacetylated Notpolyubiquitinated",
        "maps_to": "signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000706_model.nucleus_foxo1_unphosphorylated_unacetylated_notpolyubiquitinated",
        "description": "Nucleus Foxo1 Unphosphorylated Unacetylated Notpolyubiquitinated. Maps to SBML symbol `nucleus_Foxo1_Pa0_Ac0_pUb0` and is emitted in native SBML units."
      },
      {
        "name": "dnabound_foxo1_unphosphorylated_unacetylated_notpolyubiquitinated",
        "label": "Dnabound Foxo1 Unphosphorylated Unacetylated Notpolyubiquitinated",
        "maps_to": "signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000706_model.dnabound_foxo1_unphosphorylated_unacetylated_notpolyubiquitinated",
        "description": "Dnabound Foxo1 Unphosphorylated Unacetylated Notpolyubiquitinated. Maps to SBML symbol `dnabound_Foxo1_Pa0_Ac0_pUb0` and is emitted in native SBML units."
      },
      {
        "name": "state",
        "label": "Observable state",
        "maps_to": "signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000706_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation summary",
        "maps_to": "signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000706_model.summary"
      },
      {
        "name": "species_labels",
        "label": "Observable labels",
        "maps_to": "signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000706_model.species_labels"
      }
    ]
  },
  "tags": [
    "signaling",
    "systems",
    "systems-biology",
    "sbml",
    "faithful",
    "biomodels_ebi",
    "cellular-signaling"
  ],
  "title": "Smith2010 - Response of FOXO Transcription Factors to Post-Translational Modifications (with acetylation pathway) Lab",
  "models": [
    {
      "path": "owned/models/signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000706_model",
      "alias": "signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000706_model",
      "provenance": {
        "owned_path": "owned/models/signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000706_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000706_model_state"
      ],
      "from": "signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000706_model.state"
    },
    {
      "to": [
        "visualisation.signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000706_model_summary"
      ],
      "from": "signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000706_model.summary"
    },
    {
      "to": [
        "visualisation.signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000706_model_species_labels"
      ],
      "from": "signaling_sbml_smith2010_response_of_foxo_transcription_factors_biomd0000000706_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "Clean Biosimulant lab for systems signaling model: Smith2010 - Response of FOXO Transcription Factors to Post-Translational Modifications (with acetylation pathway). Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.",
  "schema_version": "2.0"
}