Hayer2005 Camkii Nopka Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_act_ca_mkii_minus_psd",
        "label": "Initial Act Ca Mkii Minus Psd",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_nopka_model3_model9086926384_model.initial_act_ca_mkii_minus_psd",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `actCaMKII_minus_PSD`."
      },
      {
        "name": "initial_nmdar",
        "label": "Initial Nmdar",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_nopka_model3_model9086926384_model.initial_nmdar",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `NMDAR`."
      },
      {
        "name": "initial_ca_m_slash_ca_m_minus_psd",
        "label": "Initial Ca M Slash Ca M Minus Psd",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_nopka_model3_model9086926384_model.initial_ca_m_slash_ca_m_minus_psd",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `CaM_slash_CaM_minus_PSD`."
      },
      {
        "name": "initial_ca_m_slash_ca_m",
        "label": "Initial Ca M Slash Ca M",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_nopka_model3_model9086926384_model.initial_ca_m_slash_ca_m",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `CaM_slash_CaM`."
      },
      {
        "name": "initial_tot_ca_mkii_cyt",
        "label": "Initial Tot Ca Mkii Cyt",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_nopka_model3_model9086926384_model.initial_tot_ca_mkii_cyt",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `tot_CaMKII_cyt`."
      },
      {
        "name": "initial_ca_mkii_slash_ca_mkii",
        "label": "Initial Ca Mkii Slash Ca Mkii",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_nopka_model3_model9086926384_model.initial_ca_mkii_slash_ca_mkii",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `CaMKII_slash_CaMKII`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_nopka_model3_model9086926384_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_nopka_model3_model9086926384_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_nopka_model3_model9086926384_model.species_labels"
      },
      {
        "name": "act_ca_mkii_minus_psd",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_nopka_model3_model9086926384_model.act_ca_mkii_minus_psd"
      },
      {
        "name": "nmdar",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_nopka_model3_model9086926384_model.nmdar"
      },
      {
        "name": "ca_m_slash_ca_m_minus_psd",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_nopka_model3_model9086926384_model.ca_m_slash_ca_m_minus_psd"
      },
      {
        "name": "ca_m_slash_ca_m",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_nopka_model3_model9086926384_model.ca_m_slash_ca_m"
      },
      {
        "name": "tot_ca_mkii_cyt",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_nopka_model3_model9086926384_model.tot_ca_mkii_cyt"
      },
      {
        "name": "ca_mkii_slash_ca_mkii",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_nopka_model3_model9086926384_model.ca_mkii_slash_ca_mkii"
      }
    ]
  },
  "tags": [
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Hayer2005 Camkii Nopka Lab",
  "models": [
    {
      "path": "owned/models/systemsbiology_sbml_hayer2005_camkii_nopka_model3_model9086926384_model",
      "alias": "systemsbiology_sbml_hayer2005_camkii_nopka_model3_model9086926384_model",
      "provenance": {
        "owned_path": "owned/models/systemsbiology_sbml_hayer2005_camkii_nopka_model3_model9086926384_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.systemsbiology_sbml_hayer2005_camkii_nopka_model3_model9086926384_model_state"
      ],
      "from": "systemsbiology_sbml_hayer2005_camkii_nopka_model3_model9086926384_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_hayer2005_camkii_nopka_model3_model9086926384_model_summary"
      ],
      "from": "systemsbiology_sbml_hayer2005_camkii_nopka_model3_model9086926384_model.summary"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_hayer2005_camkii_nopka_model3_model9086926384_model_species_labels"
      ],
      "from": "systemsbiology_sbml_hayer2005_camkii_nopka_model3_model9086926384_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "This is the model of CaMKII bistability, model 3. It exhibits bistability in CaMKII activation due to autophosphorylation at the PSD and local saturation of PP1.",
  "schema_version": "2.0"
}