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Soni2018 - IL6 induced M2 Phenotype in Leishmania major infected macrophage Lab

About lab

IL-6 has been proposed to favor the development of Th2 responses and play an important role in the communication between cells of multicellular organisms. They are involved in the regulation of comple.

Runtime

Duration10
Comms Step1

Runs

Total0
Completed0
Failed0

Metadata

Packagesoni2018-il6-induced-m2-phenotype-in-leishmania-major-infected-m
Created2026-05-15
Updated2026-05-15
immunologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_interferon_gamma_interferon_gamma_receptor",
        "label": "Initial Interferon Gamma Interferon Gamma Receptor",
        "units": "native source value",
        "default": 800,
        "maps_to": "immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model.initial_interferon_gamma_interferon_gamma_receptor",
        "description": "Initial Interferon Gamma Interferon Gamma Receptor. Sets the initial value of bundled SBML species `mwd7270399_0429_4c85_920a_de2e0ae74440`."
      }
    ],
    "outputs": [
      {
        "name": "interferon_g",
        "maps_to": "immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model.interferon_g"
      },
      {
        "name": "interferon_gr",
        "maps_to": "immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model.interferon_gr"
      },
      {
        "name": "interferon_gamma_interferon_gamma_receptor",
        "maps_to": "immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model.interferon_gamma_interferon_gamma_receptor"
      },
      {
        "name": "unresolved_infection_observable_1",
        "maps_to": "immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model.unresolved_infection_observable_1"
      },
      {
        "name": "toll_like_receptor_6_complex",
        "maps_to": "immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model.toll_like_receptor_6_complex"
      },
      {
        "name": "state",
        "maps_to": "immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model.state"
      },
      {
        "name": "summary",
        "maps_to": "immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model.species_labels"
      }
    ]
  },
  "title": "Soni2018 - IL6 induced M2 Phenotype in Leishmania major infected macrophage Lab",
  "models": [
    {
      "path": "owned/models/immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model",
      "alias": "immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model",
      "provenance": {
        "owned_path": "owned/models/immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model_state"
      ],
      "from": "immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model.state"
    },
    {
      "to": [
        "visualisation.immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model_summary"
      ],
      "from": "immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model.summary"
    },
    {
      "to": [
        "visualisation.immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model_species_labels"
      ],
      "from": "immunology_sbml_soni2018_il6_induced_m2_phenotype_in_leishmania_biomd0000000873_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "IL-6 has been proposed to favor the development of Th2 responses and play an important role in the communication between cells of multicellular organisms. They are involved in the regulation of comple.",
  "schema_version": "2.0"
}

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