Hayer2005 Camkii Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_ac_slash_atp",
        "label": "Initial Ac Slash ATP",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_model3_model9086953089_model.initial_ac_slash_atp",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `AC_slash_ATP`."
      },
      {
        "name": "initial_act_ca_mkii_minus_psd",
        "label": "Initial Act Ca Mkii Minus Psd",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_model3_model9086953089_model.initial_act_ca_mkii_minus_psd",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `actCaMKII_minus_PSD`."
      },
      {
        "name": "initial_nmdar",
        "label": "Initial Nmdar",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_model3_model9086953089_model.initial_nmdar",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `NMDAR`."
      },
      {
        "name": "initial_ca_m_slash_ca_m_minus_psd",
        "label": "Initial Ca M Slash Ca M Minus Psd",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_model3_model9086953089_model.initial_ca_m_slash_ca_m_minus_psd",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `CaM_slash_CaM_minus_PSD`."
      },
      {
        "name": "initial_ca_m_slash_ca_m",
        "label": "Initial Ca M Slash Ca M",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_model3_model9086953089_model.initial_ca_m_slash_ca_m",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `CaM_slash_CaM`."
      },
      {
        "name": "initial_tot_ca_mkii_cyt",
        "label": "Initial Tot Ca Mkii Cyt",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_model3_model9086953089_model.initial_tot_ca_mkii_cyt",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `tot_CaMKII_cyt`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_model3_model9086953089_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_model3_model9086953089_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_model3_model9086953089_model.species_labels"
      },
      {
        "name": "ac_slash_atp",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_model3_model9086953089_model.ac_slash_atp"
      },
      {
        "name": "act_ca_mkii_minus_psd",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_model3_model9086953089_model.act_ca_mkii_minus_psd"
      },
      {
        "name": "nmdar",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_model3_model9086953089_model.nmdar"
      },
      {
        "name": "ca_m_slash_ca_m_minus_psd",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_model3_model9086953089_model.ca_m_slash_ca_m_minus_psd"
      },
      {
        "name": "ca_m_slash_ca_m",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_model3_model9086953089_model.ca_m_slash_ca_m"
      },
      {
        "name": "tot_ca_mkii_cyt",
        "maps_to": "systemsbiology_sbml_hayer2005_camkii_model3_model9086953089_model.tot_ca_mkii_cyt"
      }
    ]
  },
  "tags": [
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Hayer2005 Camkii Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "systemsbiology_sbml_hayer2005_camkii_model3_model9086953089_model"
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.systemsbiology_sbml_hayer2005_camkii_model3_model9086953089_model_state"
      ],
      "from": "systemsbiology_sbml_hayer2005_camkii_model3_model9086953089_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_hayer2005_camkii_model3_model9086953089_model_summary"
      ],
      "from": "systemsbiology_sbml_hayer2005_camkii_model3_model9086953089_model.summary"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_hayer2005_camkii_model3_model9086953089_model_species_labels"
      ],
      "from": "systemsbiology_sbml_hayer2005_camkii_model3_model9086953089_model.species_labels"
    }
  ],
  "package": "hayer2005-camkii",
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "version": "1.0.0",
  "description": "This is the complete model of CaMKII bistability, model 3. It exhibits bistability in CaMKII activation due to autophosphorylation at the PSD and local saturation of PP1.",
  "schema_version": "2.0"
}