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Webb2002 - Fas/FasL mediated tumor T-cell interaction Lab

About lab

Webb2002 - Fas/FasL mediated tumor T-cell interaction This deterministic model ofimmunological surveillance involving tumour cell–T-lymphocyteinteraction, cell surface expression of Fas/FasL, and thei. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.

Runtime

Duration10
Comms Step1

Runs

Total0
Completed0
Failed0

Metadata

Packagewebb2002-fas-fasl-mediated-tumor-t-cell-interaction-lab
Created2026-05-15
Updated2026-05-15
immunologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_t_cells_t",
        "label": "Initial T Cells T",
        "units": "native source value",
        "default": 500.000000000001,
        "maps_to": "immunology_sbml_webb2002_fas_fasl_mediated_tumor_t_cell_interact_biomd0000000661_model.initial_t_cells_t",
        "description": "Initial T Cells T. Sets the initial value of bundled SBML species `T`."
      },
      {
        "name": "initial_tumour_cells_m",
        "label": "Initial Tumour Cells M",
        "units": "native source value",
        "default": 500.000000000001,
        "maps_to": "immunology_sbml_webb2002_fas_fasl_mediated_tumor_t_cell_interact_biomd0000000661_model.initial_tumour_cells_m",
        "description": "Initial Tumour Cells M. Sets the initial value of bundled SBML species `m`."
      },
      {
        "name": "initial_mfasl_lt",
        "label": "Initial Mfasl Lt",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_webb2002_fas_fasl_mediated_tumor_t_cell_interact_biomd0000000661_model.initial_mfasl_lt",
        "description": "Initial Mfasl Lt. Sets the initial value of bundled SBML species `LT`."
      },
      {
        "name": "initial_fasr_rt",
        "label": "Initial Fasr Rt",
        "units": "native source value",
        "default": 10000.0000000001,
        "maps_to": "immunology_sbml_webb2002_fas_fasl_mediated_tumor_t_cell_interact_biomd0000000661_model.initial_fasr_rt",
        "description": "Initial Fasr Rt. Sets the initial value of bundled SBML species `RT`."
      },
      {
        "name": "initial_mfasl_lm",
        "label": "Initial Mfasl Lm",
        "units": "native source value",
        "default": 1000,
        "maps_to": "immunology_sbml_webb2002_fas_fasl_mediated_tumor_t_cell_interact_biomd0000000661_model.initial_mfasl_lm",
        "description": "Initial Mfasl Lm. Sets the initial value of bundled SBML species `Lm`."
      }
    ],
    "outputs": [
      {
        "name": "t_cells_t",
        "maps_to": "immunology_sbml_webb2002_fas_fasl_mediated_tumor_t_cell_interact_biomd0000000661_model.t_cells_t"
      },
      {
        "name": "tumour_cells_m",
        "maps_to": "immunology_sbml_webb2002_fas_fasl_mediated_tumor_t_cell_interact_biomd0000000661_model.tumour_cells_m"
      },
      {
        "name": "mfasl_lt",
        "maps_to": "immunology_sbml_webb2002_fas_fasl_mediated_tumor_t_cell_interact_biomd0000000661_model.mfasl_lt"
      },
      {
        "name": "fasr_rt",
        "maps_to": "immunology_sbml_webb2002_fas_fasl_mediated_tumor_t_cell_interact_biomd0000000661_model.fasr_rt"
      },
      {
        "name": "mfasl_lm",
        "maps_to": "immunology_sbml_webb2002_fas_fasl_mediated_tumor_t_cell_interact_biomd0000000661_model.mfasl_lm"
      },
      {
        "name": "state",
        "maps_to": "immunology_sbml_webb2002_fas_fasl_mediated_tumor_t_cell_interact_biomd0000000661_model.state"
      },
      {
        "name": "summary",
        "maps_to": "immunology_sbml_webb2002_fas_fasl_mediated_tumor_t_cell_interact_biomd0000000661_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "immunology_sbml_webb2002_fas_fasl_mediated_tumor_t_cell_interact_biomd0000000661_model.species_labels"
      }
    ]
  },
  "title": "Webb2002 - Fas/FasL mediated tumor T-cell interaction Lab",
  "models": [
    {
      "path": "owned/models/immunology_sbml_webb2002_fas_fasl_mediated_tumor_t_cell_interact_biomd0000000661_model",
      "alias": "immunology_sbml_webb2002_fas_fasl_mediated_tumor_t_cell_interact_biomd0000000661_model",
      "provenance": {
        "owned_path": "owned/models/immunology_sbml_webb2002_fas_fasl_mediated_tumor_t_cell_interact_biomd0000000661_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.immunology_sbml_webb2002_fas_fasl_mediated_tumor_t_cell_interact_biomd0000000661_model_state"
      ],
      "from": "immunology_sbml_webb2002_fas_fasl_mediated_tumor_t_cell_interact_biomd0000000661_model.state"
    },
    {
      "to": [
        "visualisation.immunology_sbml_webb2002_fas_fasl_mediated_tumor_t_cell_interact_biomd0000000661_model_summary"
      ],
      "from": "immunology_sbml_webb2002_fas_fasl_mediated_tumor_t_cell_interact_biomd0000000661_model.summary"
    },
    {
      "to": [
        "visualisation.immunology_sbml_webb2002_fas_fasl_mediated_tumor_t_cell_interact_biomd0000000661_model_species_labels"
      ],
      "from": "immunology_sbml_webb2002_fas_fasl_mediated_tumor_t_cell_interact_biomd0000000661_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "Webb2002 - Fas/FasL mediated tumor T-cell interaction This deterministic model ofimmunological surveillance involving tumour cell–T-lymphocyteinteraction, cell surface expression of Fas/FasL, and thei. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
  "schema_version": "2.0"
}

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