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Caydasi2012 Ubiquitous Inactive Tem1 GAP Model Lab

About lab

Single-model lab wrapper for Caydasi2012 - Regulation of Tem1 by the GAP complex in Spindle Position Checkpoint - Ubiquitous inactive model. Regulation of Tem1 by the GAP complex inSpindle Position Checkpoint - Ubiquitous inactive This model is described in the article: A dynamical model of the spindle position checkpoint. It can be used to explore cell-cycle regulation dynamics and compare checkpoint behavior across conditions.

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Metadata

Packagecaydasi2012-ubiquitous-inactive-tem1-gap-model-lab
Created2026-05-15
Updated2026-05-15
cellcyclesbmlbiomodels_ebifaithfulvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "active_bfa1_at_the_spb",
        "label": "Active Bfa1 At The SPB",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.active_bfa1_at_the_spb",
        "description": "Controls Active Bfa1 At The SPB in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.active_bfa1_at_the_spb`."
      },
      {
        "name": "active_bfa1_at_the_cytosol",
        "label": "Active Bfa1 At The Cytosol",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.active_bfa1_at_the_cytosol",
        "description": "Controls Active Bfa1 At The Cytosol in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.active_bfa1_at_the_cytosol`."
      },
      {
        "name": "active_tem1_at_the_spb",
        "label": "Active Tem1 At The SPB",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.active_tem1_at_the_spb",
        "description": "Controls Active Tem1 At The SPB in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.active_tem1_at_the_spb`."
      },
      {
        "name": "active_tem1_in_the_cytosol",
        "label": "Active Tem1 In The Cytosol",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.active_tem1_in_the_cytosol",
        "description": "Controls Active Tem1 In The Cytosol in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.active_tem1_in_the_cytosol`."
      },
      {
        "name": "inactive_bfa1_at_the_spb",
        "label": "Inactive Bfa1 At The SPB",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.inactive_bfa1_at_the_spb",
        "description": "Controls Inactive Bfa1 At The SPB in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.inactive_bfa1_at_the_spb`."
      },
      {
        "name": "inactive_bfa1_in_the_cytosol",
        "label": "Inactive Bfa1 In The Cytosol",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.inactive_bfa1_in_the_cytosol",
        "description": "Controls Inactive Bfa1 In The Cytosol in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.inactive_bfa1_in_the_cytosol`."
      }
    ],
    "outputs": [
      {
        "name": "model_state_b",
        "label": "Model state B",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.model_state_b",
        "description": "Tracks Model state B in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.model_state_b`."
      },
      {
        "name": "model_state_t",
        "label": "Model state T",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.model_state_t",
        "description": "Tracks Model state T in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.model_state_t`."
      },
      {
        "name": "bfa1_spindle_checkpoint_gap",
        "label": "Bfa1 spindle checkpoint GAP",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.bfa1_spindle_checkpoint_gap",
        "description": "Tracks Bfa1 spindle checkpoint GAP in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.bfa1_spindle_checkpoint_gap`."
      },
      {
        "name": "bfa1_phosphorylated_state_p4",
        "label": "Bfa1 phosphorylated state P4",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.bfa1_phosphorylated_state_p4",
        "description": "Tracks Bfa1 phosphorylated state P4 in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.bfa1_phosphorylated_state_p4`."
      },
      {
        "name": "bfa1_phosphorylated_state_p5",
        "label": "Bfa1 phosphorylated state P5",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.bfa1_phosphorylated_state_p5",
        "description": "Tracks Bfa1 phosphorylated state P5 in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.bfa1_phosphorylated_state_p5`."
      },
      {
        "name": "phosphorylated_tem1gt",
        "label": "Phosphorylated Tem1GT",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_tem1gt",
        "description": "Tracks Phosphorylated Tem1GT in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_tem1gt`."
      },
      {
        "name": "phosphorylated_tem1gd",
        "label": "Phosphorylated Tem1GD",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_tem1gd",
        "description": "Tracks Phosphorylated Tem1GD in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_tem1gd`."
      },
      {
        "name": "b_bfa1",
        "label": "B Bfa1",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.b_bfa1",
        "description": "Tracks B Bfa1 in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.b_bfa1`."
      },
      {
        "name": "b_bfa1p4",
        "label": "B Bfa1P4",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.b_bfa1p4",
        "description": "Tracks B Bfa1P4 in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.b_bfa1p4`."
      },
      {
        "name": "b_bfa1p5",
        "label": "B Bfa1P5",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.b_bfa1p5",
        "description": "Tracks B Bfa1P5 in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.b_bfa1p5`."
      },
      {
        "name": "phosphorylated_t_tem1gt",
        "label": "Phosphorylated T Tem1GT",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_t_tem1gt",
        "description": "Tracks Phosphorylated T Tem1GT in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_t_tem1gt`."
      },
      {
        "name": "phosphorylated_t_tem1gd",
        "label": "Phosphorylated T Tem1GD",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_t_tem1gd",
        "description": "Tracks Phosphorylated T Tem1GD in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_t_tem1gd`."
      },
      {
        "name": "phosphorylated_b_bfa1_tem1gt",
        "label": "Phosphorylated B Bfa1 Tem1GT",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_b_bfa1_tem1gt",
        "description": "Tracks Phosphorylated B Bfa1 Tem1GT in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_b_bfa1_tem1gt`."
      },
      {
        "name": "phosphorylated_b_bfa1p4_tem1gt",
        "label": "Phosphorylated B Bfa1P4 Tem1GT",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_b_bfa1p4_tem1gt",
        "description": "Tracks Phosphorylated B Bfa1P4 Tem1GT in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_b_bfa1p4_tem1gt`."
      },
      {
        "name": "phosphorylated_b_bfa1p5_tem1gt",
        "label": "Phosphorylated B Bfa1P5 Tem1GT",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_b_bfa1p5_tem1gt",
        "description": "Tracks Phosphorylated B Bfa1P5 Tem1GT in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_b_bfa1p5_tem1gt`."
      },
      {
        "name": "phosphorylated_b_bfa1_tem1gd",
        "label": "Phosphorylated B Bfa1 Tem1GD",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_b_bfa1_tem1gd",
        "description": "Tracks Phosphorylated B Bfa1 Tem1GD in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_b_bfa1_tem1gd`."
      },
      {
        "name": "phosphorylated_b_bfa1p4_tem1gd",
        "label": "Phosphorylated B Bfa1P4 Tem1GD",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_b_bfa1p4_tem1gd",
        "description": "Tracks Phosphorylated B Bfa1P4 Tem1GD in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_b_bfa1p4_tem1gd`."
      },
      {
        "name": "phosphorylated_b_bfa1p5_tem1gd",
        "label": "Phosphorylated B Bfa1P5 Tem1GD",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_b_bfa1p5_tem1gd",
        "description": "Tracks Phosphorylated B Bfa1P5 Tem1GD in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_b_bfa1p5_tem1gd`."
      },
      {
        "name": "phosphorylated_bfa1_tem1gt",
        "label": "Phosphorylated Bfa1 Tem1GT",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_bfa1_tem1gt",
        "description": "Tracks Phosphorylated Bfa1 Tem1GT in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_bfa1_tem1gt`."
      },
      {
        "name": "phosphorylated_bfa1p4_tem1gt",
        "label": "Phosphorylated Bfa1P4 Tem1GT",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_bfa1p4_tem1gt",
        "description": "Tracks Phosphorylated Bfa1P4 Tem1GT in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_bfa1p4_tem1gt`."
      },
      {
        "name": "phosphorylated_bfa1p5_tem1gt",
        "label": "Phosphorylated Bfa1P5 Tem1GT",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_bfa1p5_tem1gt",
        "description": "Tracks Phosphorylated Bfa1P5 Tem1GT in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_bfa1p5_tem1gt`."
      },
      {
        "name": "phosphorylated_bfa1_tem1gd",
        "label": "Phosphorylated Bfa1 Tem1GD",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_bfa1_tem1gd",
        "description": "Tracks Phosphorylated Bfa1 Tem1GD in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_bfa1_tem1gd`."
      },
      {
        "name": "phosphorylated_bfa1p4_tem1gd",
        "label": "Phosphorylated Bfa1P4 Tem1GD",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_bfa1p4_tem1gd",
        "description": "Tracks Phosphorylated Bfa1P4 Tem1GD in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_bfa1p4_tem1gd`."
      },
      {
        "name": "phosphorylated_bfa1p5_tem1gd",
        "label": "Phosphorylated Bfa1P5 Tem1GD",
        "maps_to": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_bfa1p5_tem1gd",
        "description": "Tracks Phosphorylated Bfa1P5 Tem1GD in the lab model via `cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.phosphorylated_bfa1p5_tem1gd`."
      }
    ]
  },
  "title": "Caydasi2012 Ubiquitous Inactive Tem1 GAP Model Lab",
  "models": [
    {
      "path": "owned/models/cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model",
      "alias": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model",
      "provenance": {
        "owned_path": "owned/models/cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model_state"
      ],
      "from": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.state"
    },
    {
      "to": [
        "visualisation.cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model_summary"
      ],
      "from": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.summary"
    },
    {
      "to": [
        "visualisation.cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model_species_labels"
      ],
      "from": "cellcycle_sbml_caydasi2012_regulation_of_tem1_by_the_gap_comple_biomd0000000702_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "Single-model lab wrapper for Caydasi2012 - Regulation of Tem1 by the GAP complex in Spindle Position Checkpoint - Ubiquitous inactive model. Regulation of Tem1 by the GAP complex inSpindle Position Checkpoint - Ubiquitous inactive This model is described in the article: A dynamical model of the spindle position checkpoint. It can be used to explore cell-cycle regulation dynamics and compare checkpoint behavior across conditions.",
  "schema_version": "2.0"
}

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