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Evans2004 Cell Based Mathematical Model Of Topotecan Lab

About lab

A two compartment mathematical model of the antineoplastic compound topotecan. It can be used to explore systemsbiology evans2004 cell based mathematical of dynamics and compare simulation behavior across conditions.

Runtime

Duration1
Comms Step0.1

Runs

Total0
Completed0
Failed0

Metadata

Packageevans2004-cell-based-mathematical-model-of-topotecan-lab
Created2026-05-17
Updated2026-05-17
systemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_model_state_l_m",
        "label": "Initial Model State L M",
        "maps_to": "systemsbiology_sbml_evans2004_cell_based_mathematical_model_of_topot_biomd0000000945_model.initial_model_state_l_m",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `L_m`."
      },
      {
        "name": "initial_model_state_l_n",
        "label": "Initial Model State L N",
        "maps_to": "systemsbiology_sbml_evans2004_cell_based_mathematical_model_of_topot_biomd0000000945_model.initial_model_state_l_n",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `L_n`."
      },
      {
        "name": "initial_model_state_l_c",
        "label": "Initial Model State L C",
        "maps_to": "systemsbiology_sbml_evans2004_cell_based_mathematical_model_of_topot_biomd0000000945_model.initial_model_state_l_c",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `L_c`."
      },
      {
        "name": "initial_model_state_h_m",
        "label": "Initial Model State H M",
        "maps_to": "systemsbiology_sbml_evans2004_cell_based_mathematical_model_of_topot_biomd0000000945_model.initial_model_state_h_m",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `H_m`."
      },
      {
        "name": "initial_model_state_h_c",
        "label": "Initial Model State H C",
        "maps_to": "systemsbiology_sbml_evans2004_cell_based_mathematical_model_of_topot_biomd0000000945_model.initial_model_state_h_c",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `H_c`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_evans2004_cell_based_mathematical_model_of_topot_biomd0000000945_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_evans2004_cell_based_mathematical_model_of_topot_biomd0000000945_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_evans2004_cell_based_mathematical_model_of_topot_biomd0000000945_model.species_labels"
      },
      {
        "name": "l_m",
        "maps_to": "systemsbiology_sbml_evans2004_cell_based_mathematical_model_of_topot_biomd0000000945_model.l_m"
      },
      {
        "name": "l_n",
        "maps_to": "systemsbiology_sbml_evans2004_cell_based_mathematical_model_of_topot_biomd0000000945_model.l_n"
      },
      {
        "name": "l_c",
        "maps_to": "systemsbiology_sbml_evans2004_cell_based_mathematical_model_of_topot_biomd0000000945_model.l_c"
      },
      {
        "name": "h_m",
        "maps_to": "systemsbiology_sbml_evans2004_cell_based_mathematical_model_of_topot_biomd0000000945_model.h_m"
      },
      {
        "name": "h_c",
        "maps_to": "systemsbiology_sbml_evans2004_cell_based_mathematical_model_of_topot_biomd0000000945_model.h_c"
      }
    ]
  },
  "tags": [
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Evans2004 Cell Based Mathematical Model Of Topotecan Lab",
  "models": [
    {
      "path": "owned/models/systemsbiology_sbml_evans2004_cell_based_mathematical_model_of_topot_biomd0000000945_model",
      "alias": "systemsbiology_sbml_evans2004_cell_based_mathematical_model_of_topot_biomd0000000945_model",
      "provenance": {
        "owned_path": "owned/models/systemsbiology_sbml_evans2004_cell_based_mathematical_model_of_topot_biomd0000000945_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.systemsbiology_sbml_evans2004_cell_based_mathematical_model_of_topot_biomd0000000945_model_state"
      ],
      "from": "systemsbiology_sbml_evans2004_cell_based_mathematical_model_of_topot_biomd0000000945_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_evans2004_cell_based_mathematical_model_of_topot_biomd0000000945_model_summary"
      ],
      "from": "systemsbiology_sbml_evans2004_cell_based_mathematical_model_of_topot_biomd0000000945_model.summary"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_evans2004_cell_based_mathematical_model_of_topot_biomd0000000945_model_species_labels"
      ],
      "from": "systemsbiology_sbml_evans2004_cell_based_mathematical_model_of_topot_biomd0000000945_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "A two compartment mathematical model of the antineoplastic compound topotecan. It can be used to explore systemsbiology evans2004 cell based mathematical of dynamics and compare simulation behavior across conditions.",
  "schema_version": "2.0"
}

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