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Ciliberto2003 - Mathematical Morphogenesis Checkpoint Budding Yeast Cell Lab

About lab

Source-faithful physiology lab for Ciliberto, Novak, Tyson, 2003. Public controls and outputs are mapped to real source symbols for source-model physiology.

Runtime

Duration0.01
Comms Step0.01
Settle Steps1

Runs

Total0
Completed0
Failed0

Metadata

Packageciliberto2003-mathematical-morphogenesis-checkpoint-budding-yeas
Created2026-05-23
Updated2026-05-23
physiologycellmlphysiomefaithfulvisualisationother

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_cell_cycle_state_m",
        "label": "Initial Cell Cycle State M (source M)",
        "maps_to": "physiology_cellml_ciliberto_novak_tyson_2003_36c_model.initial_cell_cycle_state_m",
        "description": "Initial value for Cell Cycle State M (source M). Maps to source symbol `M`. Units: dimensionless. Naming evidence: cell-cycle or mitotic context supports a conservative source-state label.",
        "accepted_units": [
          "dimensionless"
        ]
      },
      {
        "name": "initial_bud_emergence_state_be",
        "label": "Initial Bud Emergence State Be (source BE)",
        "maps_to": "physiology_cellml_ciliberto_novak_tyson_2003_36c_model.initial_bud_emergence_state_be",
        "description": "Initial value for Bud Emergence State Be (source BE). Maps to source symbol `BE`. Units: dimensionless. Naming evidence: cell-cycle or mitotic context supports a conservative source-state label.",
        "accepted_units": [
          "dimensionless"
        ]
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Selected Source State",
        "maps_to": "physiology_cellml_ciliberto_novak_tyson_2003_36c_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation Summary",
        "maps_to": "physiology_cellml_ciliberto_novak_tyson_2003_36c_model.summary"
      },
      {
        "name": "trajectory",
        "label": "Source Trajectory",
        "maps_to": "physiology_cellml_ciliberto_novak_tyson_2003_36c_model.trajectory"
      },
      {
        "name": "variable_labels",
        "label": "Observable Labels",
        "maps_to": "physiology_cellml_ciliberto_novak_tyson_2003_36c_model.variable_labels"
      },
      {
        "name": "bud_emergence_state_be",
        "label": "Bud Emergence State Be (source BE)",
        "maps_to": "physiology_cellml_ciliberto_novak_tyson_2003_36c_model.bud_emergence_state_be",
        "description": "Bud Emergence State Be (source BE). Maps to source symbol `BE`. Units: dimensionless. Naming evidence: cell-cycle or mitotic context supports a conservative source-state label."
      },
      {
        "name": "cdc20",
        "label": "Cdc20",
        "maps_to": "physiology_cellml_ciliberto_novak_tyson_2003_36c_model.cdc20",
        "description": "Cdc20. Maps to source symbol `Cdc20`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "cdc20_a",
        "label": "Cdc20 A",
        "maps_to": "physiology_cellml_ciliberto_novak_tyson_2003_36c_model.cdc20_a",
        "description": "Cdc20 A. Maps to source symbol `Cdc20_a`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "cdh1_a",
        "label": "Cdh1 A",
        "maps_to": "physiology_cellml_ciliberto_novak_tyson_2003_36c_model.cdh1_a",
        "description": "Cdh1 A. Maps to source symbol `Cdh1_a`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "clb2",
        "label": "Clb2",
        "maps_to": "physiology_cellml_ciliberto_novak_tyson_2003_36c_model.clb2",
        "description": "Clb2. Maps to source symbol `Clb2`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "cln",
        "label": "Cln",
        "maps_to": "physiology_cellml_ciliberto_novak_tyson_2003_36c_model.cln",
        "description": "Cln. Maps to source symbol `Cln`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
      }
    ]
  },
  "title": "Ciliberto2003 - Mathematical Morphogenesis Checkpoint Budding Yeast Cell Lab",
  "models": [
    {
      "path": "owned/models/physiology_cellml_ciliberto_novak_tyson_2003_36c_model",
      "alias": "physiology_cellml_ciliberto_novak_tyson_2003_36c_model",
      "parameters": {
        "model_path": "data/ciliberto_novak_tyson_2003.cellml",
        "integration_step": 0.01
      },
      "provenance": {
        "owned_path": "owned/models/physiology_cellml_ciliberto_novak_tyson_2003_36c_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.physiology_cellml_ciliberto_novak_tyson_2003_36c_model_state"
      ],
      "from": "physiology_cellml_ciliberto_novak_tyson_2003_36c_model.state"
    },
    {
      "to": [
        "visualisation.physiology_cellml_ciliberto_novak_tyson_2003_36c_model_summary"
      ],
      "from": "physiology_cellml_ciliberto_novak_tyson_2003_36c_model.summary"
    },
    {
      "to": [
        "visualisation.physiology_cellml_ciliberto_novak_tyson_2003_36c_model_trajectory"
      ],
      "from": "physiology_cellml_ciliberto_novak_tyson_2003_36c_model.trajectory"
    },
    {
      "to": [
        "visualisation.physiology_cellml_ciliberto_novak_tyson_2003_36c_model_variable_labels"
      ],
      "from": "physiology_cellml_ciliberto_novak_tyson_2003_36c_model.variable_labels"
    }
  ],
  "runtime": {
    "duration": 0.01,
    "settle_steps": 1,
    "initial_inputs": {},
    "communication_step": 0.01
  },
  "description": "Source-faithful physiology lab for Ciliberto, Novak, Tyson, 2003. Public controls and outputs are mapped to real source symbols for source-model physiology.",
  "schema_version": "2.0"
}

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