Egli2004 Prolactinrhythmicsecretion Lab

About lab

Egli2004 Prolactinrhythmicsecretion

This Biosimulant lab wraps Egli2004 Prolactinrhythmicsecretion as a runnable systems biology model with a companion visualization module. This a model from the article: Rhythmic secretion of prolactin in rats: action of oxytocin coordinated byvasoactive intestinal polypeptide of suprachiasmatic nucleus origin. It can be used to explore the configured dynamics and compare scenario outcomes across configurations.

What You'll See

The lab asks: Which source-defined system states dominate this SBML model trajectory? Source model: Egli2004_ProlactinRhythmicSecretion. It runs for 1.0 time units with a communication step of 0.1. The run uses the model defaults declared by the curated SBML wrapper. The generated visualizations focus on PRL, OT, and DA, combining trajectory, endpoint-comparison, and summary-table views from one completed dark-mode run.

In this captured run, OT moved from 25.000 to 22.964 across 1.0 simulation windows.

Output Visualizations

Egli2004 Prolactinrhythmicsecretion - run interpretation

Summary table for Egli2004 Prolactinrhythmicsecretion, reporting the scientific question, observed answer, dominant module, and caveat.

Egli2004 Prolactinrhythmicsecretion - timeseries visualization

Trajectories of OT, PRL, and DA across the 1.0 simulation. In this run OT fell from 25.000 to 22.964 — the largest movements among the focused observables.

Egli2004 Prolactinrhythmicsecretion - excursions bar

Largest-excursion ranking of the focused observables — the absolute movement magnitude during the run. Top 2: OT = 2.036, PRL = 1.615.

Egli2004 Prolactinrhythmicsecretion - endpoint snapshot bar

Endpoint snapshot of the focused observables — final values from the captured run. Top 3 by value: DA = 2e+04, OT = 22.964, PRL = 18.385.

Egli2004 Prolactinrhythmicsecretion - visualization

Visualization card from the Egli2004 Prolactinrhythmicsecretion dark-mode run.

Model Context

Core model: models/core
Visualization model: models/visualisation
Standard: other
Upstream source: biomodels_ebi:MODEL0912452142
License: CC0

Inputs

Input	Maps To	Notes
Initial Model State Prl	`systemsbiology_sbml_egli2004_prolactinrhythmicsecretion_model0912452142_model.initial_model_state_prl`	Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `PRL`.
Initial Model State Ot	`systemsbiology_sbml_egli2004_prolactinrhythmicsecretion_model0912452142_model.initial_model_state_ot`	Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `OT`.
Initial Model State Da	`systemsbiology_sbml_egli2004_prolactinrhythmicsecretion_model0912452142_model.initial_model_state_da`	Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `DA`.

Outputs

Output	Maps To	Role
`state`	`systemsbiology_sbml_egli2004_prolactinrhythmicsecretion_model0912452142_model.state`	Available to the visualization model and downstream workflows.
`summary`	`systemsbiology_sbml_egli2004_prolactinrhythmicsecretion_model0912452142_model.summary`	Available to the visualization model and downstream workflows.
`species_labels`	`systemsbiology_sbml_egli2004_prolactinrhythmicsecretion_model0912452142_model.species_labels`	Available to the visualization model and downstream workflows.
`prl`	`systemsbiology_sbml_egli2004_prolactinrhythmicsecretion_model0912452142_model.prl`	Available to the visualization model and downstream workflows.
`model_state_ot`	`systemsbiology_sbml_egli2004_prolactinrhythmicsecretion_model0912452142_model.model_state_ot`	Available to the visualization model and downstream workflows.
`model_state_da`	`systemsbiology_sbml_egli2004_prolactinrhythmicsecretion_model0912452142_model.model_state_da`	Available to the visualization model and downstream workflows.

Runtime

Duration: 1.0
Communication step: 0.1

Running Locally

biosimulant labs serve

This a model from the article: Rhythmic secretion of prolactin in rats: action of oxytocin coordinated byvasoactive intestinal polypeptide of suprachiasmatic nucleus origin. It can be used to explore systemsbiology egli2004 prolactinrhythmicsecreti model0912452142 dynamics and compare simulation behavior across conditions.

Runtime

Duration1

Comms Step0.1

Runs

Total0

Completed0

Failed0

Metadata

Packageegli2004-prolactinrhythmicsecretion-lab

Created2026-05-17

Updated2026-05-17

systemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_model_state_prl",
        "label": "Initial Model State Prl",
        "maps_to": "systemsbiology_sbml_egli2004_prolactinrhythmicsecretion_model0912452142_model.initial_model_state_prl",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `PRL`."
      },
      {
        "name": "initial_model_state_ot",
        "label": "Initial Model State Ot",
        "maps_to": "systemsbiology_sbml_egli2004_prolactinrhythmicsecretion_model0912452142_model.initial_model_state_ot",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `OT`."
      },
      {
        "name": "initial_model_state_da",
        "label": "Initial Model State Da",
        "maps_to": "systemsbiology_sbml_egli2004_prolactinrhythmicsecretion_model0912452142_model.initial_model_state_da",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `DA`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_egli2004_prolactinrhythmicsecretion_model0912452142_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_egli2004_prolactinrhythmicsecretion_model0912452142_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_egli2004_prolactinrhythmicsecretion_model0912452142_model.species_labels"
      },
      {
        "name": "prl",
        "maps_to": "systemsbiology_sbml_egli2004_prolactinrhythmicsecretion_model0912452142_model.prl"
      },
      {
        "name": "model_state_ot",
        "maps_to": "systemsbiology_sbml_egli2004_prolactinrhythmicsecretion_model0912452142_model.model_state_ot"
      },
      {
        "name": "model_state_da",
        "maps_to": "systemsbiology_sbml_egli2004_prolactinrhythmicsecretion_model0912452142_model.model_state_da"
      }
    ]
  },
  "tags": [
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Egli2004 Prolactinrhythmicsecretion Lab",
  "models": [
    {
      "path": "owned/models/systemsbiology_sbml_egli2004_prolactinrhythmicsecretion_model0912452142_model",
      "alias": "systemsbiology_sbml_egli2004_prolactinrhythmicsecretion_model0912452142_model",
      "provenance": {
        "owned_path": "owned/models/systemsbiology_sbml_egli2004_prolactinrhythmicsecretion_model0912452142_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.systemsbiology_sbml_egli2004_prolactinrhythmicsecretion_model0912452142_model_state"
      ],
      "from": "systemsbiology_sbml_egli2004_prolactinrhythmicsecretion_model0912452142_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_egli2004_prolactinrhythmicsecretion_model0912452142_model_summary"
      ],
      "from": "systemsbiology_sbml_egli2004_prolactinrhythmicsecretion_model0912452142_model.summary"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_egli2004_prolactinrhythmicsecretion_model0912452142_model_species_labels"
      ],
      "from": "systemsbiology_sbml_egli2004_prolactinrhythmicsecretion_model0912452142_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "This a model from the article: Rhythmic secretion of prolactin in rats: action of oxytocin coordinated byvasoactive intestinal polypeptide of suprachiasmatic nucleus origin. It can be used to explore systemsbiology egli2004 prolactinrhythmicsecreti model0912452142 dynamics and compare simulation behavior across conditions.",
  "schema_version": "2.0"
}

Select a run from History to view its results.