Clarke2006 Smad Signalling Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_r_smad_cyt",
        "label": "Initial R Smad Cyt",
        "maps_to": "systemsbiology_sbml_clarke2006_smad_signalling_biomd0000000112_model.initial_r_smad_cyt",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `R_smad_cyt`."
      },
      {
        "name": "initial_smad4_cyt",
        "label": "Initial Smad4 Cyt",
        "maps_to": "systemsbiology_sbml_clarke2006_smad_signalling_biomd0000000112_model.initial_smad4_cyt",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `smad4_cyt`."
      },
      {
        "name": "initial_smad4_nuc",
        "label": "Initial Smad4 Nuc",
        "maps_to": "systemsbiology_sbml_clarke2006_smad_signalling_biomd0000000112_model.initial_smad4_nuc",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `smad4_nuc`."
      },
      {
        "name": "initial_r_smad_nuc",
        "label": "Initial R Smad Nuc",
        "maps_to": "systemsbiology_sbml_clarke2006_smad_signalling_biomd0000000112_model.initial_r_smad_nuc",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `R_smad_nuc`."
      },
      {
        "name": "initial_receptors",
        "label": "Initial Receptors",
        "maps_to": "systemsbiology_sbml_clarke2006_smad_signalling_biomd0000000112_model.initial_receptors",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `receptor`."
      },
      {
        "name": "initial_r_smad_p_nuc",
        "label": "Initial R Smad P Nuc",
        "maps_to": "systemsbiology_sbml_clarke2006_smad_signalling_biomd0000000112_model.initial_r_smad_p_nuc",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `R_smad_P_nuc`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_clarke2006_smad_signalling_biomd0000000112_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_clarke2006_smad_signalling_biomd0000000112_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_clarke2006_smad_signalling_biomd0000000112_model.species_labels"
      },
      {
        "name": "r_smad_cyt",
        "maps_to": "systemsbiology_sbml_clarke2006_smad_signalling_biomd0000000112_model.r_smad_cyt"
      },
      {
        "name": "smad4_cyt",
        "maps_to": "systemsbiology_sbml_clarke2006_smad_signalling_biomd0000000112_model.smad4_cyt"
      },
      {
        "name": "smad4_nuc",
        "maps_to": "systemsbiology_sbml_clarke2006_smad_signalling_biomd0000000112_model.smad4_nuc"
      },
      {
        "name": "r_smad_nuc",
        "maps_to": "systemsbiology_sbml_clarke2006_smad_signalling_biomd0000000112_model.r_smad_nuc"
      },
      {
        "name": "receptors",
        "maps_to": "systemsbiology_sbml_clarke2006_smad_signalling_biomd0000000112_model.receptors"
      },
      {
        "name": "r_smad_p_nuc",
        "maps_to": "systemsbiology_sbml_clarke2006_smad_signalling_biomd0000000112_model.r_smad_p_nuc"
      }
    ]
  },
  "tags": [
    "signaling",
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Clarke2006 Smad Signalling Lab",
  "models": [
    {
      "path": "owned/models/systemsbiology_sbml_clarke2006_smad_signalling_biomd0000000112_model",
      "alias": "systemsbiology_sbml_clarke2006_smad_signalling_biomd0000000112_model",
      "provenance": {
        "owned_path": "owned/models/systemsbiology_sbml_clarke2006_smad_signalling_biomd0000000112_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.systemsbiology_sbml_clarke2006_smad_signalling_biomd0000000112_model_state"
      ],
      "from": "systemsbiology_sbml_clarke2006_smad_signalling_biomd0000000112_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_clarke2006_smad_signalling_biomd0000000112_model_summary"
      ],
      "from": "systemsbiology_sbml_clarke2006_smad_signalling_biomd0000000112_model.summary"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_clarke2006_smad_signalling_biomd0000000112_model_species_labels"
      ],
      "from": "systemsbiology_sbml_clarke2006_smad_signalling_biomd0000000112_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "The model reproduces the temporal evolution of four variables depicted in Fig 2a. It can be used to explore systemsbiology clarke2006 smad signalling BioModels0000000112 dynamics and compare simulation behavior across conditions.",
  "schema_version": "2.0"
}