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Wodarz2018/2 - model with transit amplifying cells Lab

About lab

The paper describes a model of effect of cellular de-differentiation on the dynamics and evolution of tissue and tumor cells. Created by COPASI 4.25 (Build 207) This model is described in the article:.

Runtime

Duration10
Comms Step1

Runs

Total0
Completed0
Failed0

Metadata

Packagewodarz2018-2-model-with-transit-amplifying-cells-lab
Created2026-05-16
Updated2026-05-16
biomodels_ebicuratedfaithfuloncologyphysiologysbmlsystemsbiologytumor-growthvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_stem_like_cells",
        "label": "Stem-Like Cells",
        "units": "native SBML value",
        "default": 1,
        "maps_to": "oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model.initial_stem_like_cells",
        "description": "Initial Stem-Like Cells. Sets the initial value of bundled SBML symbol `S`."
      },
      {
        "name": "initial_transit_amplifying_cells",
        "label": "Transit-Amplifying Cells",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model.initial_transit_amplifying_cells",
        "description": "Initial Transit-Amplifying Cells. Sets the initial value of bundled SBML symbol `T`."
      },
      {
        "name": "initial_differentiated_cells",
        "label": "Differentiated Cells",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model.initial_differentiated_cells",
        "description": "Initial Differentiated Cells. Sets the initial value of bundled SBML symbol `D`."
      }
    ],
    "outputs": [
      {
        "name": "stem_like_cells",
        "maps_to": "oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model.stem_like_cells",
        "description": "Stem-Like Cells observable. Maps to SBML symbol `S`."
      },
      {
        "name": "transit_amplifying_cells",
        "maps_to": "oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model.transit_amplifying_cells",
        "description": "Transit-Amplifying Cells observable. Maps to SBML symbol `T`."
      },
      {
        "name": "differentiated_cells",
        "maps_to": "oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model.differentiated_cells",
        "description": "Differentiated Cells observable. Maps to SBML symbol `D`."
      },
      {
        "name": "state",
        "maps_to": "oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model.state",
        "description": "Full raw SBML observable record for reproducibility and downstream visualisation."
      },
      {
        "name": "summary",
        "maps_to": "oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model.summary",
        "description": "Change and peak summary across the simulated SBML observables."
      },
      {
        "name": "species_labels",
        "maps_to": "oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model.species_labels",
        "description": "Mapping from selected raw SBML observable symbols to display labels."
      }
    ]
  },
  "tags": [
    "biomodels_ebi",
    "curated",
    "faithful",
    "oncology",
    "physiology",
    "sbml",
    "systemsbiology",
    "tumor-growth"
  ],
  "title": "Wodarz2018/2 - model with transit amplifying cells Lab",
  "models": [
    {
      "path": "owned/models/oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model",
      "alias": "oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model",
      "provenance": {
        "owned_path": "owned/models/oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model_state"
      ],
      "from": "oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model.state"
    },
    {
      "to": [
        "visualisation.oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model_summary"
      ],
      "from": "oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model.summary"
    },
    {
      "to": [
        "visualisation.oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model_species_labels"
      ],
      "from": "oncology_sbml_wodarz2018_2_model_with_transit_amplifying_cells_biomd0000000773_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "The paper describes a model of effect of cellular de-differentiation on the dynamics and evolution of tissue and tumor cells. Created by COPASI 4.25 (Build 207) This model is described in the article:.",
  "schema_version": "2.0"
}

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