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Phillips2007 Ascendingarousalsystem Sleepwakedynamics Lab

About lab

This a model from the article: A quantitative model of sleep-wake dynamics based on the physiology of thebrainstem ascending arousal system. It can be used to explore systemsbiology phillips2007 ascendingarousalsystem sleepwakedyn BioModels0000000917 dynamics and compare simulation behavior across conditions.

Runtime

Duration1
Comms Step0.1

Runs

Total0
Completed0
Failed0

Metadata

Packagephillips2007-ascendingarousalsystem-sleepwakedynamics-lab
Created2026-05-17
Updated2026-05-17
physiologysystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_somnogen_level_h",
        "label": "Initial Somnogen Level H",
        "maps_to": "systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model.initial_somnogen_level_h",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Somnogen_level_H`."
      },
      {
        "name": "initial_ventrolateral_preopticarea_vlpo_voltage",
        "label": "Initial Ventrolateral Preopticarea Vlpo Voltage",
        "maps_to": "systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model.initial_ventrolateral_preopticarea_vlpo_voltage",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Ventrolateral_preopticarea__VLPO__voltage`."
      },
      {
        "name": "initial_monoaminergic_ma_voltage",
        "label": "Initial Monoaminergic Ma Voltage",
        "maps_to": "systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model.initial_monoaminergic_ma_voltage",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `Monoaminergic__MA__voltage`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model.species_labels"
      },
      {
        "name": "somnogen_level_h",
        "maps_to": "systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model.somnogen_level_h"
      },
      {
        "name": "ventrolateral_preopticarea_vlpo_voltage",
        "maps_to": "systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model.ventrolateral_preopticarea_vlpo_voltage"
      },
      {
        "name": "monoaminergic_ma_voltage",
        "maps_to": "systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model.monoaminergic_ma_voltage"
      }
    ]
  },
  "tags": [
    "physiology",
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Phillips2007 Ascendingarousalsystem Sleepwakedynamics Lab",
  "models": [
    {
      "path": "owned/models/systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model",
      "alias": "systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model",
      "provenance": {
        "owned_path": "owned/models/systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model_state"
      ],
      "from": "systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model_summary"
      ],
      "from": "systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model.summary"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model_species_labels"
      ],
      "from": "systemsbiology_sbml_phillips2007_ascendingarousalsystem_sleepwakedyn_biomd0000000917_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "This a model from the article: A quantitative model of sleep-wake dynamics based on the physiology of thebrainstem ascending arousal system. It can be used to explore systemsbiology phillips2007 ascendingarousalsystem sleepwakedyn BioModels0000000917 dynamics and compare simulation behavior across conditions.",
  "schema_version": "2.0"
}

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