BiosimulantBiosimulant
Docs
Search labs...
Sign inGet Started

Jarrett2018 - trastuzumab-induced immune response in murine HER2+ breast cancer model Lab

About lab

The paper describes a model on the trastuzumab-induced immune response in murine(mouse) HER2+ breast cancer.Created by COPASI 4.25 (Build 207) This model is described in the article: Mathematical mode. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.

Runtime

Duration10
Comms Step1

Runs

Total0
Completed0
Failed0

Metadata

Packagejarrett2018-trastuzumab-induced-immune-response-in-murine-her2-b
Created2026-05-15
Updated2026-05-15
immunologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_unresolved_tumor_observable_1",
        "label": "Initial Unresolved Tumor Observable 1",
        "units": "substance",
        "default": 0.2,
        "maps_to": "immunology_sbml_jarrett2018_trastuzumab_induced_immune_response_biomd0000000745_model.initial_unresolved_tumor_observable_1",
        "description": "Initial Unresolved Tumor Observable 1. Sets the initial value of bundled SBML species `T`."
      },
      {
        "name": "initial_unresolved_tumor_observable_2",
        "label": "Initial Unresolved Tumor Observable 2",
        "units": "substance",
        "default": 0.071,
        "maps_to": "immunology_sbml_jarrett2018_trastuzumab_induced_immune_response_biomd0000000745_model.initial_unresolved_tumor_observable_2",
        "description": "Initial Unresolved Tumor Observable 2. Sets the initial value of bundled SBML species `I`."
      },
      {
        "name": "initial_unresolved_tumor_observable_3",
        "label": "Initial Unresolved Tumor Observable 3",
        "units": "substance",
        "default": 0.12,
        "maps_to": "immunology_sbml_jarrett2018_trastuzumab_induced_immune_response_biomd0000000745_model.initial_unresolved_tumor_observable_3",
        "description": "Initial Unresolved Tumor Observable 3. Sets the initial value of bundled SBML species `V`."
      },
      {
        "name": "initial_unresolved_tumor_observable_4",
        "label": "Initial Unresolved Tumor Observable 4",
        "units": "substance",
        "default": 0.1,
        "maps_to": "immunology_sbml_jarrett2018_trastuzumab_induced_immune_response_biomd0000000745_model.initial_unresolved_tumor_observable_4",
        "description": "Initial Unresolved Tumor Observable 4. Sets the initial value of bundled SBML species `N`."
      },
      {
        "name": "initial_unresolved_tumor_observable_5",
        "label": "Initial Unresolved Tumor Observable 5",
        "units": "substance",
        "default": 0.18,
        "maps_to": "immunology_sbml_jarrett2018_trastuzumab_induced_immune_response_biomd0000000745_model.initial_unresolved_tumor_observable_5",
        "description": "Initial Unresolved Tumor Observable 5. Sets the initial value of bundled SBML species `H`."
      }
    ],
    "outputs": [
      {
        "name": "unresolved_tumor_observable_1",
        "maps_to": "immunology_sbml_jarrett2018_trastuzumab_induced_immune_response_biomd0000000745_model.unresolved_tumor_observable_1"
      },
      {
        "name": "unresolved_tumor_observable_2",
        "maps_to": "immunology_sbml_jarrett2018_trastuzumab_induced_immune_response_biomd0000000745_model.unresolved_tumor_observable_2"
      },
      {
        "name": "unresolved_tumor_observable_3",
        "maps_to": "immunology_sbml_jarrett2018_trastuzumab_induced_immune_response_biomd0000000745_model.unresolved_tumor_observable_3"
      },
      {
        "name": "unresolved_tumor_observable_4",
        "maps_to": "immunology_sbml_jarrett2018_trastuzumab_induced_immune_response_biomd0000000745_model.unresolved_tumor_observable_4"
      },
      {
        "name": "unresolved_tumor_observable_5",
        "maps_to": "immunology_sbml_jarrett2018_trastuzumab_induced_immune_response_biomd0000000745_model.unresolved_tumor_observable_5"
      },
      {
        "name": "state",
        "maps_to": "immunology_sbml_jarrett2018_trastuzumab_induced_immune_response_biomd0000000745_model.state"
      },
      {
        "name": "summary",
        "maps_to": "immunology_sbml_jarrett2018_trastuzumab_induced_immune_response_biomd0000000745_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "immunology_sbml_jarrett2018_trastuzumab_induced_immune_response_biomd0000000745_model.species_labels"
      }
    ]
  },
  "title": "Jarrett2018 - trastuzumab-induced immune response in murine HER2+ breast cancer model Lab",
  "models": [
    {
      "path": "owned/models/immunology_sbml_jarrett2018_trastuzumab_induced_immune_response_biomd0000000745_model",
      "alias": "immunology_sbml_jarrett2018_trastuzumab_induced_immune_response_biomd0000000745_model",
      "provenance": {
        "owned_path": "owned/models/immunology_sbml_jarrett2018_trastuzumab_induced_immune_response_biomd0000000745_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.immunology_sbml_jarrett2018_trastuzumab_induced_immune_response_biomd0000000745_model_state"
      ],
      "from": "immunology_sbml_jarrett2018_trastuzumab_induced_immune_response_biomd0000000745_model.state"
    },
    {
      "to": [
        "visualisation.immunology_sbml_jarrett2018_trastuzumab_induced_immune_response_biomd0000000745_model_summary"
      ],
      "from": "immunology_sbml_jarrett2018_trastuzumab_induced_immune_response_biomd0000000745_model.summary"
    },
    {
      "to": [
        "visualisation.immunology_sbml_jarrett2018_trastuzumab_induced_immune_response_biomd0000000745_model_species_labels"
      ],
      "from": "immunology_sbml_jarrett2018_trastuzumab_induced_immune_response_biomd0000000745_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "The paper describes a model on the trastuzumab-induced immune response in murine(mouse) HER2+ breast cancer.Created by COPASI 4.25 (Build 207) This model is described in the article: Mathematical mode. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
  "schema_version": "2.0"
}

Sign in to start your own run. Public-lab history stays visible here.

Select a run from History to view its results.