Zhu2015 - Combined gemcitabine and birinapant in pancreatic cancer cells - basic PD model Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_sti_g1",
        "label": "Sti g1",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "oncology_sbml_zhu2015_combined_gemcitabine_and_birinapant_in_p_biomd0000000668_model.initial_sti_g1",
        "description": "Initial Sti g1. Sets the initial value of bundled SBML symbol `Sti_g1`."
      },
      {
        "name": "initial_sti_g2",
        "label": "Sti g2",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "oncology_sbml_zhu2015_combined_gemcitabine_and_birinapant_in_p_biomd0000000668_model.initial_sti_g2",
        "description": "Initial Sti g2. Sets the initial value of bundled SBML symbol `Sti_g2`."
      },
      {
        "name": "initial_sti_g3",
        "label": "Sti g3",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "oncology_sbml_zhu2015_combined_gemcitabine_and_birinapant_in_p_biomd0000000668_model.initial_sti_g3",
        "description": "Initial Sti g3. Sets the initial value of bundled SBML symbol `Sti_g3`."
      },
      {
        "name": "initial_sti_g4",
        "label": "Sti g4",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "oncology_sbml_zhu2015_combined_gemcitabine_and_birinapant_in_p_biomd0000000668_model.initial_sti_g4",
        "description": "Initial Sti g4. Sets the initial value of bundled SBML symbol `Sti_g4`."
      },
      {
        "name": "initial_sti_b1",
        "label": "Sti b1",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "oncology_sbml_zhu2015_combined_gemcitabine_and_birinapant_in_p_biomd0000000668_model.initial_sti_b1",
        "description": "Initial Sti b1. Sets the initial value of bundled SBML symbol `Sti_b1`."
      },
      {
        "name": "initial_sti_b2",
        "label": "Sti b2",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "oncology_sbml_zhu2015_combined_gemcitabine_and_birinapant_in_p_biomd0000000668_model.initial_sti_b2",
        "description": "Initial Sti b2. Sets the initial value of bundled SBML symbol `Sti_b2`."
      }
    ],
    "outputs": [
      {
        "name": "sti_g1",
        "maps_to": "oncology_sbml_zhu2015_combined_gemcitabine_and_birinapant_in_p_biomd0000000668_model.sti_g1",
        "description": "Sti g1 observable. Maps to SBML symbol `Sti_g1`."
      },
      {
        "name": "sti_g2",
        "maps_to": "oncology_sbml_zhu2015_combined_gemcitabine_and_birinapant_in_p_biomd0000000668_model.sti_g2",
        "description": "Sti g2 observable. Maps to SBML symbol `Sti_g2`."
      },
      {
        "name": "sti_g3",
        "maps_to": "oncology_sbml_zhu2015_combined_gemcitabine_and_birinapant_in_p_biomd0000000668_model.sti_g3",
        "description": "Sti g3 observable. Maps to SBML symbol `Sti_g3`."
      },
      {
        "name": "sti_g4",
        "maps_to": "oncology_sbml_zhu2015_combined_gemcitabine_and_birinapant_in_p_biomd0000000668_model.sti_g4",
        "description": "Sti g4 observable. Maps to SBML symbol `Sti_g4`."
      },
      {
        "name": "sti_b1",
        "maps_to": "oncology_sbml_zhu2015_combined_gemcitabine_and_birinapant_in_p_biomd0000000668_model.sti_b1",
        "description": "Sti b1 observable. Maps to SBML symbol `Sti_b1`."
      },
      {
        "name": "sti_b2",
        "maps_to": "oncology_sbml_zhu2015_combined_gemcitabine_and_birinapant_in_p_biomd0000000668_model.sti_b2",
        "description": "Sti b2 observable. Maps to SBML symbol `Sti_b2`."
      },
      {
        "name": "state",
        "maps_to": "oncology_sbml_zhu2015_combined_gemcitabine_and_birinapant_in_p_biomd0000000668_model.state",
        "description": "Full raw SBML observable record for reproducibility and downstream visualisation."
      },
      {
        "name": "summary",
        "maps_to": "oncology_sbml_zhu2015_combined_gemcitabine_and_birinapant_in_p_biomd0000000668_model.summary",
        "description": "Change and peak summary across the simulated SBML observables."
      },
      {
        "name": "species_labels",
        "maps_to": "oncology_sbml_zhu2015_combined_gemcitabine_and_birinapant_in_p_biomd0000000668_model.species_labels",
        "description": "Mapping from selected raw SBML observable symbols to display labels."
      }
    ]
  },
  "tags": [
    "biomodels_ebi",
    "chemotherapy",
    "curated",
    "drug-response",
    "faithful",
    "oncology",
    "pharmacology",
    "physiology",
    "sbml",
    "systemsbiology",
    "tumor-growth"
  ],
  "title": "Zhu2015 - Combined gemcitabine and birinapant in pancreatic cancer cells - basic PD model Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "oncology_sbml_zhu2015_combined_gemcitabine_and_birinapant_in_p_biomd0000000668_model"
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.oncology_sbml_zhu2015_combined_gemcitabine_and_birinapant_in_p_biomd0000000668_model_state"
      ],
      "from": "oncology_sbml_zhu2015_combined_gemcitabine_and_birinapant_in_p_biomd0000000668_model.state"
    },
    {
      "to": [
        "visualisation.oncology_sbml_zhu2015_combined_gemcitabine_and_birinapant_in_p_biomd0000000668_model_summary"
      ],
      "from": "oncology_sbml_zhu2015_combined_gemcitabine_and_birinapant_in_p_biomd0000000668_model.summary"
    },
    {
      "to": [
        "visualisation.oncology_sbml_zhu2015_combined_gemcitabine_and_birinapant_in_p_biomd0000000668_model_species_labels"
      ],
      "from": "oncology_sbml_zhu2015_combined_gemcitabine_and_birinapant_in_p_biomd0000000668_model.species_labels"
    }
  ],
  "package": "zhu2015-combined-gemcitabine-and-birinapant-in-pancreat-8ba36cfe",
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "version": "1.0.0",
  "description": "Zhu2015 - Combined gemcitabine and birinapantin pancreatic cancer cells - basic PD model Mathematical model to illustrate theeffectiveness of combination chemotherapy involving gemcitabine andbirinapa. It can be used to explore tumor-related dynamics and compare treatment-response behavior across conditions.",
  "schema_version": "2.0"
}