Cursons2015 - Regulation of ERK-MAPK signaling in human epidermis Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_calcium_amp_level",
        "label": "calcium AMP",
        "maps_to": "signaling_sbml_cursons2015_regulation_of_erk_mapk_signaling_in_biomd0000000659_model.initial_calcium_amp_level",
        "description": "calcium AMP source parameter. Maps to SBML symbol `numCaInputAmp` and preserves the bundled default."
      },
      {
        "name": "initial_calcium_baseline_level",
        "label": "calcium Baseline",
        "maps_to": "signaling_sbml_cursons2015_regulation_of_erk_mapk_signaling_in_biomd0000000659_model.initial_calcium_baseline_level",
        "description": "calcium Baseline source parameter. Maps to SBML symbol `numCaInputBaseline` and preserves the bundled default."
      },
      {
        "name": "initial_calcium_m_amp_level",
        "label": "calcium M AMP",
        "maps_to": "signaling_sbml_cursons2015_regulation_of_erk_mapk_signaling_in_biomd0000000659_model.initial_calcium_m_amp_level",
        "description": "calcium M AMP source parameter. Maps to SBML symbol `numCaMInputAmp` and preserves the bundled default."
      }
    ],
    "outputs": [
      {
        "name": "cytosolic_phosphorylated_erk",
        "label": "cytosolic phosphorylated ERK",
        "maps_to": "signaling_sbml_cursons2015_regulation_of_erk_mapk_signaling_in_biomd0000000659_model.cytosolic_phosphorylated_erk",
        "description": "cytosolic phosphorylated ERK. Maps to SBML symbol `pERK_cyto` and is emitted in native SBML units."
      },
      {
        "name": "nuclear_phosphorylated_erk",
        "label": "nuclear phosphorylated ERK",
        "maps_to": "signaling_sbml_cursons2015_regulation_of_erk_mapk_signaling_in_biomd0000000659_model.nuclear_phosphorylated_erk",
        "description": "nuclear phosphorylated ERK. Maps to SBML symbol `pERK_nuc` and is emitted in native SBML units."
      },
      {
        "name": "calmodulin",
        "label": "calmodulin",
        "maps_to": "signaling_sbml_cursons2015_regulation_of_erk_mapk_signaling_in_biomd0000000659_model.calmodulin",
        "description": "calmodulin. Maps to SBML symbol `CaM_memb` and is emitted in native SBML units."
      },
      {
        "name": "state",
        "label": "Observable state",
        "maps_to": "signaling_sbml_cursons2015_regulation_of_erk_mapk_signaling_in_biomd0000000659_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation summary",
        "maps_to": "signaling_sbml_cursons2015_regulation_of_erk_mapk_signaling_in_biomd0000000659_model.summary"
      },
      {
        "name": "species_labels",
        "label": "Observable labels",
        "maps_to": "signaling_sbml_cursons2015_regulation_of_erk_mapk_signaling_in_biomd0000000659_model.species_labels"
      }
    ]
  },
  "tags": [
    "signaling",
    "systems",
    "systems-biology",
    "sbml",
    "faithful",
    "biomodels_ebi",
    "mapk",
    "ras-erk",
    "calcium-signaling",
    "gpcr"
  ],
  "title": "Cursons2015 - Regulation of ERK-MAPK signaling in human epidermis Lab",
  "models": [
    {
      "path": "owned/models/signaling_sbml_cursons2015_regulation_of_erk_mapk_signaling_in_biomd0000000659_model",
      "alias": "signaling_sbml_cursons2015_regulation_of_erk_mapk_signaling_in_biomd0000000659_model",
      "provenance": {
        "owned_path": "owned/models/signaling_sbml_cursons2015_regulation_of_erk_mapk_signaling_in_biomd0000000659_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.signaling_sbml_cursons2015_regulation_of_erk_mapk_signaling_in_biomd0000000659_model_state"
      ],
      "from": "signaling_sbml_cursons2015_regulation_of_erk_mapk_signaling_in_biomd0000000659_model.state"
    },
    {
      "to": [
        "visualisation.signaling_sbml_cursons2015_regulation_of_erk_mapk_signaling_in_biomd0000000659_model_summary"
      ],
      "from": "signaling_sbml_cursons2015_regulation_of_erk_mapk_signaling_in_biomd0000000659_model.summary"
    },
    {
      "to": [
        "visualisation.signaling_sbml_cursons2015_regulation_of_erk_mapk_signaling_in_biomd0000000659_model_species_labels"
      ],
      "from": "signaling_sbml_cursons2015_regulation_of_erk_mapk_signaling_in_biomd0000000659_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "Clean Biosimulant lab for MAPK/ERK receptor signaling. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.",
  "schema_version": "2.0"
}