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Ferrel2011 - Autonomous biochemical oscillator in regulation of CDK1, Plk1, and APC in Xenopus Laevis cell cycle Lab

About lab

Single-model lab wrapper for Ferrel2011 - Autonomous biochemical oscillator in regulation of CDK1, Plk1, and APC in Xenopus Laevis cell cycle. Computational modeling and the theory of nonlinear dynamical systems allow one to not simply describe the events of the cell cycle, but also to understand why these events occur, just as the theory of. It can be used to explore cell-cycle regulation dynamics and compare checkpoint behavior across conditions.

Runtime

Duration10
Comms Step1

Runs

Total0
Completed0
Failed0

Metadata

Packageferrel2011-autonomous-biochemical-oscillator-in-regulation-of-cd
Created2026-05-15
Updated2026-05-15
cellcyclesbmlbiomodels_ebifaithfulvisualisation

Manifest

{
  "io": {
    "inputs": [],
    "outputs": [
      {
        "name": "cdk1_active",
        "label": "CDK1 Active",
        "maps_to": "cellcycle_sbml_ferrel2011_autonomous_biochemical_oscillator_in_biomd0000000937_model.cdk1_active",
        "description": "Tracks CDK1 Active in the lab model via `cellcycle_sbml_ferrel2011_autonomous_biochemical_oscillator_in_biomd0000000937_model.cdk1_active`."
      },
      {
        "name": "apc_c_c_active",
        "label": "APC/C/C Active",
        "maps_to": "cellcycle_sbml_ferrel2011_autonomous_biochemical_oscillator_in_biomd0000000937_model.apc_c_c_active",
        "description": "Tracks APC/C/C Active in the lab model via `cellcycle_sbml_ferrel2011_autonomous_biochemical_oscillator_in_biomd0000000937_model.apc_c_c_active`."
      },
      {
        "name": "plk1_active",
        "label": "Plk1 Active",
        "maps_to": "cellcycle_sbml_ferrel2011_autonomous_biochemical_oscillator_in_biomd0000000937_model.plk1_active",
        "description": "Tracks Plk1 Active in the lab model via `cellcycle_sbml_ferrel2011_autonomous_biochemical_oscillator_in_biomd0000000937_model.plk1_active`."
      }
    ]
  },
  "title": "Ferrel2011 - Autonomous biochemical oscillator in regulation of CDK1, Plk1, and APC in Xenopus Laevis cell cycle Lab",
  "models": [
    {
      "path": "owned/models/cellcycle_sbml_ferrel2011_autonomous_biochemical_oscillator_in_biomd0000000937_model",
      "alias": "cellcycle_sbml_ferrel2011_autonomous_biochemical_oscillator_in_biomd0000000937_model",
      "provenance": {
        "owned_path": "owned/models/cellcycle_sbml_ferrel2011_autonomous_biochemical_oscillator_in_biomd0000000937_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.cellcycle_sbml_ferrel2011_autonomous_biochemical_oscillator_in_biomd0000000937_model_state"
      ],
      "from": "cellcycle_sbml_ferrel2011_autonomous_biochemical_oscillator_in_biomd0000000937_model.state"
    },
    {
      "to": [
        "visualisation.cellcycle_sbml_ferrel2011_autonomous_biochemical_oscillator_in_biomd0000000937_model_summary"
      ],
      "from": "cellcycle_sbml_ferrel2011_autonomous_biochemical_oscillator_in_biomd0000000937_model.summary"
    },
    {
      "to": [
        "visualisation.cellcycle_sbml_ferrel2011_autonomous_biochemical_oscillator_in_biomd0000000937_model_species_labels"
      ],
      "from": "cellcycle_sbml_ferrel2011_autonomous_biochemical_oscillator_in_biomd0000000937_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "Single-model lab wrapper for Ferrel2011 - Autonomous biochemical oscillator in regulation of CDK1, Plk1, and APC in Xenopus Laevis cell cycle. Computational modeling and the theory of nonlinear dynamical systems allow one to not simply describe the events of the cell cycle, but also to understand why these events occur, just as the theory of. It can be used to explore cell-cycle regulation dynamics and compare checkpoint behavior across conditions.",
  "schema_version": "2.0"
}

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