dePillis2009 - Mathematical model creation for cancer chemo-immunotherapy Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_chemotherapy_drug",
        "label": "Initial Chemotherapy Drug",
        "units": "native source value",
        "default": 0,
        "maps_to": "immunology_sbml_depillis2009_mathematical_model_creation_for_can_biomd0000000779_model.initial_chemotherapy_drug",
        "description": "Initial Chemotherapy Drug. Sets the initial value of bundled SBML species `M_Chemotherapy_Drug`."
      },
      {
        "name": "initial_unresolved_tumor_observable_1",
        "label": "Initial Unresolved Tumor Observable 1",
        "units": "native source value",
        "default": 10000000,
        "maps_to": "immunology_sbml_depillis2009_mathematical_model_creation_for_can_biomd0000000779_model.initial_unresolved_tumor_observable_1",
        "description": "Initial Unresolved Tumor Observable 1. Sets the initial value of bundled SBML species `T_Tumour_Cells`."
      },
      {
        "name": "initial_cd8_t_cells",
        "label": "Initial CD8 T Cells",
        "units": "native source value",
        "default": 526800,
        "maps_to": "immunology_sbml_depillis2009_mathematical_model_creation_for_can_biomd0000000779_model.initial_cd8_t_cells",
        "description": "Initial CD8 T Cells. Sets the initial value of bundled SBML species `L_CD8_T_Cells`."
      },
      {
        "name": "initial_interleukin_2",
        "label": "Initial Interleukin 2",
        "units": "native source value",
        "default": 1073,
        "maps_to": "immunology_sbml_depillis2009_mathematical_model_creation_for_can_biomd0000000779_model.initial_interleukin_2",
        "description": "Initial Interleukin 2. Sets the initial value of bundled SBML species `I_IL_2`."
      },
      {
        "name": "initial_natural_killer_cells",
        "label": "Initial Natural Killer Cells",
        "units": "native source value",
        "default": 250000000,
        "maps_to": "immunology_sbml_depillis2009_mathematical_model_creation_for_can_biomd0000000779_model.initial_natural_killer_cells",
        "description": "Initial Natural Killer Cells. Sets the initial value of bundled SBML species `N_Natural_Killer_Cells`."
      },
      {
        "name": "natural_killer_induced_tumour_death_rate",
        "label": "Natural Killer Induced Tumour Death Rate",
        "units": "native source value",
        "default": 2.9077e-13,
        "maps_to": "immunology_sbml_depillis2009_mathematical_model_creation_for_can_biomd0000000779_model.natural_killer_induced_tumour_death_rate",
        "description": "Natural Killer Induced Tumour Death Rate. Sets bundled SBML parameter `c`."
      }
    ],
    "outputs": [
      {
        "name": "chemotherapy_drug",
        "maps_to": "immunology_sbml_depillis2009_mathematical_model_creation_for_can_biomd0000000779_model.chemotherapy_drug"
      },
      {
        "name": "unresolved_tumor_observable_1",
        "maps_to": "immunology_sbml_depillis2009_mathematical_model_creation_for_can_biomd0000000779_model.unresolved_tumor_observable_1"
      },
      {
        "name": "cd8_t_cells",
        "maps_to": "immunology_sbml_depillis2009_mathematical_model_creation_for_can_biomd0000000779_model.cd8_t_cells"
      },
      {
        "name": "interleukin_2",
        "maps_to": "immunology_sbml_depillis2009_mathematical_model_creation_for_can_biomd0000000779_model.interleukin_2"
      },
      {
        "name": "natural_killer_cells",
        "maps_to": "immunology_sbml_depillis2009_mathematical_model_creation_for_can_biomd0000000779_model.natural_killer_cells"
      },
      {
        "name": "state",
        "maps_to": "immunology_sbml_depillis2009_mathematical_model_creation_for_can_biomd0000000779_model.state"
      },
      {
        "name": "summary",
        "maps_to": "immunology_sbml_depillis2009_mathematical_model_creation_for_can_biomd0000000779_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "immunology_sbml_depillis2009_mathematical_model_creation_for_can_biomd0000000779_model.species_labels"
      }
    ]
  },
  "title": "dePillis2009 - Mathematical model creation for cancer chemo-immunotherapy Lab",
  "models": [
    {
      "path": "owned/models/immunology_sbml_depillis2009_mathematical_model_creation_for_can_biomd0000000779_model",
      "alias": "immunology_sbml_depillis2009_mathematical_model_creation_for_can_biomd0000000779_model",
      "provenance": {
        "owned_path": "owned/models/immunology_sbml_depillis2009_mathematical_model_creation_for_can_biomd0000000779_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.immunology_sbml_depillis2009_mathematical_model_creation_for_can_biomd0000000779_model_state"
      ],
      "from": "immunology_sbml_depillis2009_mathematical_model_creation_for_can_biomd0000000779_model.state"
    },
    {
      "to": [
        "visualisation.immunology_sbml_depillis2009_mathematical_model_creation_for_can_biomd0000000779_model_summary"
      ],
      "from": "immunology_sbml_depillis2009_mathematical_model_creation_for_can_biomd0000000779_model.summary"
    },
    {
      "to": [
        "visualisation.immunology_sbml_depillis2009_mathematical_model_creation_for_can_biomd0000000779_model_species_labels"
      ],
      "from": "immunology_sbml_depillis2009_mathematical_model_creation_for_can_biomd0000000779_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "This is an updated version of a previous model that described the dynamics of cancer treatment, with descriptions of tumour cell numbers, specific and non-specific immune cells (NK, CD8+ T cells and o. It can be used to explore immune response dynamics and compare pathway-level behavior across conditions.",
  "schema_version": "2.0"
}