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Haugh2004 - Mathematical Human Growth Hormone H Gh Stimulated Cell Lab

About lab

Source-faithful physiology lab for Haugh, 2004. Public controls and outputs are mapped to real source symbols for signalling physiology.

Runtime

Duration0.01
Comms Step0.01
Settle Steps1

Runs

Total0
Completed0
Failed0

Metadata

Packagehaugh2004-mathematical-human-growth-hormone-h-gh-stimulated-cell
Created2026-05-23
Updated2026-05-23
physiologycellmlphysiomefaithfulvisualisationother

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_free_h_gh_receptor",
        "label": "Initial Free H Gh Receptor",
        "maps_to": "physiology_cellml_haugh_2004_haugh2004_model.initial_free_h_gh_receptor",
        "description": "Initial value for Free H Gh Receptor. Maps to source symbol `R`. Units: nanomolar. Naming evidence: source metadata names `R` as `free hGH-receptor`.",
        "accepted_units": [
          "nanomolar"
        ]
      },
      {
        "name": "initial_internalised_h_gh_receptor",
        "label": "Initial Internalised H Gh Receptor",
        "maps_to": "physiology_cellml_haugh_2004_haugh2004_model.initial_internalised_h_gh_receptor",
        "description": "Initial value for Internalised H Gh Receptor. Maps to source symbol `Ri`. Units: nanomolar. Naming evidence: source metadata names `Ri` as `internalised hGH-receptor`.",
        "accepted_units": [
          "nanomolar"
        ]
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Selected Source State",
        "maps_to": "physiology_cellml_haugh_2004_haugh2004_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation Summary",
        "maps_to": "physiology_cellml_haugh_2004_haugh2004_model.summary"
      },
      {
        "name": "trajectory",
        "label": "Source Trajectory",
        "maps_to": "physiology_cellml_haugh_2004_haugh2004_model.trajectory"
      },
      {
        "name": "variable_labels",
        "label": "Observable Labels",
        "maps_to": "physiology_cellml_haugh_2004_haugh2004_model.variable_labels"
      },
      {
        "name": "free_h_gh_receptor",
        "label": "Free H Gh Receptor",
        "maps_to": "physiology_cellml_haugh_2004_haugh2004_model.free_h_gh_receptor",
        "description": "Free H Gh Receptor. Maps to source symbol `R`. Units: nanomolar. Naming evidence: source metadata names `R` as `free hGH-receptor`."
      },
      {
        "name": "internalised_h_gh_receptor",
        "label": "Internalised H Gh Receptor",
        "maps_to": "physiology_cellml_haugh_2004_haugh2004_model.internalised_h_gh_receptor",
        "description": "Internalised H Gh Receptor. Maps to source symbol `Ri`. Units: nanomolar. Naming evidence: source metadata names `Ri` as `internalised hGH-receptor`."
      },
      {
        "name": "var_1_1_h_gh_receptor_complex",
        "label": "Var 1 1 H Gh Receptor Complex",
        "maps_to": "physiology_cellml_haugh_2004_haugh2004_model.var_1_1_h_gh_receptor_complex",
        "description": "Var 1 1 H Gh Receptor Complex. Maps to source symbol `C`. Units: nanomolar. Naming evidence: source metadata names `C` as `1:1 hGH-receptor complex`."
      },
      {
        "name": "var_1_2_h_gh_receptor_dimer_complex",
        "label": "Var 1 2 H Gh Receptor Dimer Complex",
        "maps_to": "physiology_cellml_haugh_2004_haugh2004_model.var_1_2_h_gh_receptor_dimer_complex",
        "description": "Var 1 2 H Gh Receptor Dimer Complex. Maps to source symbol `D`. Units: nanomolar. Naming evidence: source metadata names `D` as `1:2 hGH-receptor dimer complex`."
      },
      {
        "name": "kappa_e",
        "label": "Kappa E",
        "maps_to": "physiology_cellml_haugh_2004_haugh2004_model.kappa_e",
        "description": "Kappa E. Maps to source symbol `kappaE`. Units: dimensionless. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "kdeg",
        "label": "Kdeg",
        "maps_to": "physiology_cellml_haugh_2004_haugh2004_model.kdeg",
        "description": "Kdeg. Maps to source symbol `kdeg`. Units: first_order_rate_constant. Naming evidence: source symbol, component, or units provide a direct public name."
      }
    ]
  },
  "title": "Haugh2004 - Mathematical Human Growth Hormone H Gh Stimulated Cell Lab",
  "models": [
    {
      "path": "owned/models/physiology_cellml_haugh_2004_haugh2004_model",
      "alias": "physiology_cellml_haugh_2004_haugh2004_model",
      "parameters": {
        "model_path": "data/haugh_2004.cellml",
        "integration_step": 0.01
      },
      "provenance": {
        "owned_path": "owned/models/physiology_cellml_haugh_2004_haugh2004_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.physiology_cellml_haugh_2004_haugh2004_model_state"
      ],
      "from": "physiology_cellml_haugh_2004_haugh2004_model.state"
    },
    {
      "to": [
        "visualisation.physiology_cellml_haugh_2004_haugh2004_model_summary"
      ],
      "from": "physiology_cellml_haugh_2004_haugh2004_model.summary"
    },
    {
      "to": [
        "visualisation.physiology_cellml_haugh_2004_haugh2004_model_trajectory"
      ],
      "from": "physiology_cellml_haugh_2004_haugh2004_model.trajectory"
    },
    {
      "to": [
        "visualisation.physiology_cellml_haugh_2004_haugh2004_model_variable_labels"
      ],
      "from": "physiology_cellml_haugh_2004_haugh2004_model.variable_labels"
    }
  ],
  "runtime": {
    "duration": 0.01,
    "settle_steps": 1,
    "initial_inputs": {},
    "communication_step": 0.01
  },
  "description": "Source-faithful physiology lab for Haugh, 2004. Public controls and outputs are mapped to real source symbols for signalling physiology.",
  "schema_version": "2.0"
}

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