Cui2008 - Modelling Calcium Calcineurin Signalling Network Cardiac Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_calcium_calmodulin_complex",
        "label": "Initial Calcium Calmodulin Complex",
        "maps_to": "physiology_cellml_cui_kaandorp_2008_cuikaandorp2008_model.initial_calcium_calmodulin_complex",
        "description": "Initial value for Calcium Calmodulin Complex. Maps to source symbol `CaMCa`. Units: micromolar. Naming evidence: source metadata names `CaMCa` as `calcium-calmodulin complex`.",
        "accepted_units": [
          "micromolar"
        ]
      },
      {
        "name": "initial_cytosolic_nfatp",
        "label": "Initial Cytosolic Nfatp",
        "maps_to": "physiology_cellml_cui_kaandorp_2008_cuikaandorp2008_model.initial_cytosolic_nfatp",
        "description": "Initial value for Cytosolic Nfatp. Maps to source symbol `NFATpc`. Units: micromolar. Naming evidence: source metadata names `NFATpc` as `cytosolic NFATp`.",
        "accepted_units": [
          "micromolar"
        ]
      }
    ],
    "outputs": [
      {
        "name": "state",
        "label": "Selected Source State",
        "maps_to": "physiology_cellml_cui_kaandorp_2008_cuikaandorp2008_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation Summary",
        "maps_to": "physiology_cellml_cui_kaandorp_2008_cuikaandorp2008_model.summary"
      },
      {
        "name": "trajectory",
        "label": "Source Trajectory",
        "maps_to": "physiology_cellml_cui_kaandorp_2008_cuikaandorp2008_model.trajectory"
      },
      {
        "name": "variable_labels",
        "label": "Observable Labels",
        "maps_to": "physiology_cellml_cui_kaandorp_2008_cuikaandorp2008_model.variable_labels"
      },
      {
        "name": "cytosolic_nfatp",
        "label": "Cytosolic Nfatp",
        "maps_to": "physiology_cellml_cui_kaandorp_2008_cuikaandorp2008_model.cytosolic_nfatp",
        "description": "Cytosolic Nfatp. Maps to source symbol `NFATpc`. Units: micromolar. Naming evidence: source metadata names `NFATpc` as `cytosolic NFATp`."
      },
      {
        "name": "nfatpc_ca_nc_star",
        "label": "Nfatpc Ca Nc Star",
        "maps_to": "physiology_cellml_cui_kaandorp_2008_cuikaandorp2008_model.nfatpc_ca_nc_star",
        "description": "Nfatpc Ca Nc Star. Maps to source symbol `NFATpc_CaNc_star`. Units: micromolar. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "nfatpn_ca_nn_star",
        "label": "Nfatpn Ca Nn Star",
        "maps_to": "physiology_cellml_cui_kaandorp_2008_cuikaandorp2008_model.nfatpn_ca_nn_star",
        "description": "Nfatpn Ca Nn Star. Maps to source symbol `NFATpn_CaNn_star`. Units: micromolar. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "nuclear_nfatp",
        "label": "Nuclear Nfatp",
        "maps_to": "physiology_cellml_cui_kaandorp_2008_cuikaandorp2008_model.nuclear_nfatp",
        "description": "Nuclear Nfatp. Maps to source symbol `NFATpn`. Units: micromolar. Naming evidence: source metadata names `NFATpn` as `nuclear NFATp`."
      },
      {
        "name": "calcium_concentration",
        "label": "Calcium Concentration",
        "maps_to": "physiology_cellml_cui_kaandorp_2008_cuikaandorp2008_model.calcium_concentration",
        "description": "Calcium Concentration. Maps to source symbol `Ca`. Units: micromolar. Naming evidence: source symbol, component, or units provide a direct public name."
      },
      {
        "name": "big_mitogen_activated_protein_kinase_1",
        "label": "Big Mitogen Activated Protein Kinase 1",
        "maps_to": "physiology_cellml_cui_kaandorp_2008_cuikaandorp2008_model.big_mitogen_activated_protein_kinase_1",
        "description": "Big Mitogen Activated Protein Kinase 1. Maps to source symbol `BMK1`. Units: micromolar. Naming evidence: source metadata names `BMK1` as `big mitogen-activated protein kinase 1`."
      }
    ]
  },
  "title": "Cui2008 - Modelling Calcium Calcineurin Signalling Network Cardiac Lab",
  "models": [
    {
      "path": "owned/models/physiology_cellml_cui_kaandorp_2008_cuikaandorp2008_model",
      "alias": "physiology_cellml_cui_kaandorp_2008_cuikaandorp2008_model",
      "parameters": {
        "model_path": "data/cui_kaandorp_2008.cellml",
        "integration_step": 0.01
      },
      "provenance": {
        "owned_path": "owned/models/physiology_cellml_cui_kaandorp_2008_cuikaandorp2008_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.physiology_cellml_cui_kaandorp_2008_cuikaandorp2008_model_state"
      ],
      "from": "physiology_cellml_cui_kaandorp_2008_cuikaandorp2008_model.state"
    },
    {
      "to": [
        "visualisation.physiology_cellml_cui_kaandorp_2008_cuikaandorp2008_model_summary"
      ],
      "from": "physiology_cellml_cui_kaandorp_2008_cuikaandorp2008_model.summary"
    },
    {
      "to": [
        "visualisation.physiology_cellml_cui_kaandorp_2008_cuikaandorp2008_model_trajectory"
      ],
      "from": "physiology_cellml_cui_kaandorp_2008_cuikaandorp2008_model.trajectory"
    },
    {
      "to": [
        "visualisation.physiology_cellml_cui_kaandorp_2008_cuikaandorp2008_model_variable_labels"
      ],
      "from": "physiology_cellml_cui_kaandorp_2008_cuikaandorp2008_model.variable_labels"
    }
  ],
  "runtime": {
    "duration": 0.01,
    "settle_steps": 1,
    "initial_inputs": {},
    "communication_step": 0.01
  },
  "description": "Source-faithful physiology lab for Cui, Kaandorp, 2008. Public controls and outputs are mapped to real source symbols for electrophysiology.",
  "schema_version": "2.0"
}