Tran2009_CardiacActiveForceGeneration Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_metabolic_pathway_state_1",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "metabolism_sbml_tran2009_cardiacactiveforcegeneration_model1006230116_model.initial_metabolic_pathway_state_1",
        "description": "Initial condition for metabolic pathway state 1. Maps to bundled SBML symbol `Ca_sr`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_metabolic_pathway_state_2",
        "units": "native SBML value",
        "default": 0.00016666666666666666,
        "maps_to": "metabolism_sbml_tran2009_cardiacactiveforcegeneration_model1006230116_model.initial_metabolic_pathway_state_2",
        "description": "Initial condition for metabolic pathway state 2. Maps to bundled SBML symbol `T_Cai`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from Tellurium setup-time value because no explicit SBML initial value was available."
      },
      {
        "name": "initial_metabolic_pathway_state_3",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "metabolism_sbml_tran2009_cardiacactiveforcegeneration_model1006230116_model.initial_metabolic_pathway_state_3",
        "description": "Initial condition for metabolic pathway state 3. Maps to bundled SBML symbol `T_Casr`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from Tellurium setup-time value because no explicit SBML initial value was available."
      },
      {
        "name": "initial_metabolic_pathway_state_4",
        "units": "native SBML value",
        "default": 9.174311926605505,
        "maps_to": "metabolism_sbml_tran2009_cardiacactiveforcegeneration_model1006230116_model.initial_metabolic_pathway_state_4",
        "description": "Initial condition for metabolic pathway state 4. Maps to bundled SBML symbol `T_H1`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from Tellurium setup-time value because no explicit SBML initial value was available."
      },
      {
        "name": "initial_metabolic_pathway_state_5",
        "units": "native SBML value",
        "default": 0.000002824858757062147,
        "maps_to": "metabolism_sbml_tran2009_cardiacactiveforcegeneration_model1006230116_model.initial_metabolic_pathway_state_5",
        "description": "Initial condition for metabolic pathway state 5. Maps to bundled SBML symbol `T_Hi`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from Tellurium setup-time value because no explicit SBML initial value was available."
      }
    ],
    "outputs": [
      {
        "name": "metabolic_pathway_state_1",
        "maps_to": "metabolism_sbml_tran2009_cardiacactiveforcegeneration_model1006230116_model.metabolic_pathway_state_1"
      },
      {
        "name": "metabolic_pathway_state_2",
        "maps_to": "metabolism_sbml_tran2009_cardiacactiveforcegeneration_model1006230116_model.metabolic_pathway_state_2"
      },
      {
        "name": "metabolic_pathway_state_3",
        "maps_to": "metabolism_sbml_tran2009_cardiacactiveforcegeneration_model1006230116_model.metabolic_pathway_state_3"
      },
      {
        "name": "metabolic_pathway_state_4",
        "maps_to": "metabolism_sbml_tran2009_cardiacactiveforcegeneration_model1006230116_model.metabolic_pathway_state_4"
      },
      {
        "name": "metabolic_pathway_state_5",
        "maps_to": "metabolism_sbml_tran2009_cardiacactiveforcegeneration_model1006230116_model.metabolic_pathway_state_5"
      },
      {
        "name": "observable_values",
        "maps_to": "metabolism_sbml_tran2009_cardiacactiveforcegeneration_model1006230116_model.observable_values"
      },
      {
        "name": "run_summary",
        "maps_to": "metabolism_sbml_tran2009_cardiacactiveforcegeneration_model1006230116_model.run_summary"
      },
      {
        "name": "observable_labels",
        "maps_to": "metabolism_sbml_tran2009_cardiacactiveforcegeneration_model1006230116_model.observable_labels"
      }
    ]
  },
  "title": "Tran2009_CardiacActiveForceGeneration Lab",
  "models": [
    {
      "path": "models/core",
      "alias": "metabolism_sbml_tran2009_cardiacactiveforcegeneration_model1006230116_model",
      "parameters": {
        "model_path": "data/MODEL1006230116.xml",
        "integration_step": 0.1
      }
    },
    {
      "path": "models/visualisation",
      "alias": "visualisation"
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.metabolism_sbml_tran2009_cardiacactiveforcegeneration_model1006230116_model_observable_values"
      ],
      "from": "metabolism_sbml_tran2009_cardiacactiveforcegeneration_model1006230116_model.observable_values"
    },
    {
      "to": [
        "visualisation.metabolism_sbml_tran2009_cardiacactiveforcegeneration_model1006230116_model_run_summary"
      ],
      "from": "metabolism_sbml_tran2009_cardiacactiveforcegeneration_model1006230116_model.run_summary"
    },
    {
      "to": [
        "visualisation.metabolism_sbml_tran2009_cardiacactiveforcegeneration_model1006230116_model_observable_labels"
      ],
      "from": "metabolism_sbml_tran2009_cardiacactiveforcegeneration_model1006230116_model.observable_labels"
    }
  ],
  "package": "tran2009-cardiacactiveforcegeneration",
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "version": "1.0.0",
  "description": "This a model from the article: A metabolite-sensitive, thermodynamically constrained model of cardiaccross-bridge cycling: implications for force development during ischemia. It can be used to explore metabolic flux dynamics and compare pathway behavior across conditions.",
  "schema_version": "2.0"
}