BiosimulantBiosimulant
Docs
Search labs...
Sign inGet Started

Hoefnagel2002_PyruvateBranches Lab

About lab

This a model from the article: Metabolic engineering of lactic acid bacteria, the combined approach: kinetic modelling, metabolic control and experimental analysis. It can be used to explore metabolic flux dynamics and compare pathway behavior across conditions.

Runtime

Duration10
Comms Step1

Runs

Total0
Completed0
Failed0

Metadata

Packagehoefnagel2002-pyruvatebranches-lab
Created2026-05-15
Updated2026-05-15
biomodels_ebifaithfulmetabolismodesbmltelluriumvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_adp",
        "units": "native SBML value",
        "default": 4.9,
        "maps_to": "metabolism_sbml_hoefnagel2002_pyruvatebranches_biomd0000000017_model.initial_adp",
        "description": "Initial condition for adp. Maps to bundled SBML symbol `ADP`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_nad",
        "units": "native SBML value",
        "default": 6.33,
        "maps_to": "metabolism_sbml_hoefnagel2002_pyruvatebranches_biomd0000000017_model.initial_nad",
        "description": "Initial condition for nad. Maps to bundled SBML symbol `NAD`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_atp",
        "units": "native SBML value",
        "default": 0.1,
        "maps_to": "metabolism_sbml_hoefnagel2002_pyruvatebranches_biomd0000000017_model.initial_atp",
        "description": "Initial condition for atp. Maps to bundled SBML symbol `ATP`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_nadh",
        "units": "native SBML value",
        "default": 3.67,
        "maps_to": "metabolism_sbml_hoefnagel2002_pyruvatebranches_biomd0000000017_model.initial_nadh",
        "description": "Initial condition for nadh. Maps to bundled SBML symbol `NADH`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      },
      {
        "name": "initial_metabolic_pathway_state_5",
        "units": "native SBML value",
        "default": 1,
        "maps_to": "metabolism_sbml_hoefnagel2002_pyruvatebranches_biomd0000000017_model.initial_metabolic_pathway_state_5",
        "description": "Initial condition for metabolic pathway state 5. Maps to bundled SBML symbol `pyruvate`. Applied before the Tellurium simulation starts; this does not change kinetic parameters or equations. Default from bundled SBML initial value."
      }
    ],
    "outputs": [
      {
        "name": "adp",
        "maps_to": "metabolism_sbml_hoefnagel2002_pyruvatebranches_biomd0000000017_model.adp"
      },
      {
        "name": "nad",
        "maps_to": "metabolism_sbml_hoefnagel2002_pyruvatebranches_biomd0000000017_model.nad"
      },
      {
        "name": "atp",
        "maps_to": "metabolism_sbml_hoefnagel2002_pyruvatebranches_biomd0000000017_model.atp"
      },
      {
        "name": "nadh",
        "maps_to": "metabolism_sbml_hoefnagel2002_pyruvatebranches_biomd0000000017_model.nadh"
      },
      {
        "name": "metabolic_pathway_state_5",
        "maps_to": "metabolism_sbml_hoefnagel2002_pyruvatebranches_biomd0000000017_model.metabolic_pathway_state_5"
      },
      {
        "name": "observable_values",
        "maps_to": "metabolism_sbml_hoefnagel2002_pyruvatebranches_biomd0000000017_model.observable_values"
      },
      {
        "name": "run_summary",
        "maps_to": "metabolism_sbml_hoefnagel2002_pyruvatebranches_biomd0000000017_model.run_summary"
      },
      {
        "name": "observable_labels",
        "maps_to": "metabolism_sbml_hoefnagel2002_pyruvatebranches_biomd0000000017_model.observable_labels"
      }
    ]
  },
  "title": "Hoefnagel2002_PyruvateBranches Lab",
  "models": [
    {
      "path": "owned/models/metabolism_sbml_hoefnagel2002_pyruvatebranches_biomd0000000017_model",
      "alias": "metabolism_sbml_hoefnagel2002_pyruvatebranches_biomd0000000017_model",
      "parameters": {
        "model_path": "data/BIOMD0000000017.xml",
        "integration_step": 0.1
      },
      "provenance": {
        "owned_path": "owned/models/metabolism_sbml_hoefnagel2002_pyruvatebranches_biomd0000000017_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.metabolism_sbml_hoefnagel2002_pyruvatebranches_biomd0000000017_model_observable_values"
      ],
      "from": "metabolism_sbml_hoefnagel2002_pyruvatebranches_biomd0000000017_model.observable_values"
    },
    {
      "to": [
        "visualisation.metabolism_sbml_hoefnagel2002_pyruvatebranches_biomd0000000017_model_run_summary"
      ],
      "from": "metabolism_sbml_hoefnagel2002_pyruvatebranches_biomd0000000017_model.run_summary"
    },
    {
      "to": [
        "visualisation.metabolism_sbml_hoefnagel2002_pyruvatebranches_biomd0000000017_model_observable_labels"
      ],
      "from": "metabolism_sbml_hoefnagel2002_pyruvatebranches_biomd0000000017_model.observable_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "This a model from the article: Metabolic engineering of lactic acid bacteria, the combined approach: kinetic modelling, metabolic control and experimental analysis. It can be used to explore metabolic flux dynamics and compare pathway behavior across conditions.",
  "schema_version": "2.0"
}

Sign in to start your own run. Public-lab history stays visible here.

Select a run from History to view its results.