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Jenner2018 - treatment of oncolytic virus Lab

About lab

The paper describes a model of oncolytic virotherapy. Created by COPASI 4.26 (Build 213) This model is described in the article: Mathematical Modelling of the Interaction Between Cancer Cells and an O.

Runtime

Duration10
Comms Step1

Runs

Total0
Completed0
Failed0

Metadata

Packagejenner2018-treatment-of-oncolytic-virus-lab
Created2026-05-16
Updated2026-05-16
biomodels_ebicurateddrug-responsefaithfulimmunotherapyoncologypharmacologyphysiologysbmlsystemsbiologytumor-growthvirotherapyvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_virus_load",
        "label": "Virus Load",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "oncology_sbml_jenner2018_treatment_of_oncolytic_virus_biomd0000000789_model.initial_virus_load",
        "description": "Initial Virus Load. Sets the initial value of bundled SBML symbol `V`."
      },
      {
        "name": "initial_susceptible_tumor_cells",
        "label": "Susceptible Tumor Cells",
        "units": "native SBML value",
        "default": 251000000,
        "maps_to": "oncology_sbml_jenner2018_treatment_of_oncolytic_virus_biomd0000000789_model.initial_susceptible_tumor_cells",
        "description": "Initial Susceptible Tumor Cells. Sets the initial value of bundled SBML symbol `S`."
      },
      {
        "name": "initial_infected_tumor_cells",
        "label": "Infected Tumor Cells",
        "units": "native SBML value",
        "default": 0,
        "maps_to": "oncology_sbml_jenner2018_treatment_of_oncolytic_virus_biomd0000000789_model.initial_infected_tumor_cells",
        "description": "Initial Infected Tumor Cells. Sets the initial value of bundled SBML symbol `I`."
      }
    ],
    "outputs": [
      {
        "name": "virus_load",
        "maps_to": "oncology_sbml_jenner2018_treatment_of_oncolytic_virus_biomd0000000789_model.virus_load",
        "description": "Virus Load observable. Maps to SBML symbol `V`."
      },
      {
        "name": "susceptible_tumor_cells",
        "maps_to": "oncology_sbml_jenner2018_treatment_of_oncolytic_virus_biomd0000000789_model.susceptible_tumor_cells",
        "description": "Susceptible Tumor Cells observable. Maps to SBML symbol `S`."
      },
      {
        "name": "infected_tumor_cells",
        "maps_to": "oncology_sbml_jenner2018_treatment_of_oncolytic_virus_biomd0000000789_model.infected_tumor_cells",
        "description": "Infected Tumor Cells observable. Maps to SBML symbol `I`."
      },
      {
        "name": "state",
        "maps_to": "oncology_sbml_jenner2018_treatment_of_oncolytic_virus_biomd0000000789_model.state",
        "description": "Full raw SBML observable record for reproducibility and downstream visualisation."
      },
      {
        "name": "summary",
        "maps_to": "oncology_sbml_jenner2018_treatment_of_oncolytic_virus_biomd0000000789_model.summary",
        "description": "Change and peak summary across the simulated SBML observables."
      },
      {
        "name": "species_labels",
        "maps_to": "oncology_sbml_jenner2018_treatment_of_oncolytic_virus_biomd0000000789_model.species_labels",
        "description": "Mapping from selected raw SBML observable symbols to display labels."
      }
    ]
  },
  "tags": [
    "biomodels_ebi",
    "curated",
    "drug-response",
    "faithful",
    "immunotherapy",
    "oncology",
    "pharmacology",
    "physiology",
    "sbml",
    "systemsbiology",
    "tumor-growth",
    "virotherapy"
  ],
  "title": "Jenner2018 - treatment of oncolytic virus Lab",
  "models": [
    {
      "path": "owned/models/oncology_sbml_jenner2018_treatment_of_oncolytic_virus_biomd0000000789_model",
      "alias": "oncology_sbml_jenner2018_treatment_of_oncolytic_virus_biomd0000000789_model",
      "provenance": {
        "owned_path": "owned/models/oncology_sbml_jenner2018_treatment_of_oncolytic_virus_biomd0000000789_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.oncology_sbml_jenner2018_treatment_of_oncolytic_virus_biomd0000000789_model_state"
      ],
      "from": "oncology_sbml_jenner2018_treatment_of_oncolytic_virus_biomd0000000789_model.state"
    },
    {
      "to": [
        "visualisation.oncology_sbml_jenner2018_treatment_of_oncolytic_virus_biomd0000000789_model_summary"
      ],
      "from": "oncology_sbml_jenner2018_treatment_of_oncolytic_virus_biomd0000000789_model.summary"
    },
    {
      "to": [
        "visualisation.oncology_sbml_jenner2018_treatment_of_oncolytic_virus_biomd0000000789_model_species_labels"
      ],
      "from": "oncology_sbml_jenner2018_treatment_of_oncolytic_virus_biomd0000000789_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "The paper describes a model of oncolytic virotherapy. Created by COPASI 4.26 (Build 213) This model is described in the article: Mathematical Modelling of the Interaction Between Cancer Cells and an O.",
  "schema_version": "2.0"
}

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