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Mclean1991 Behaviour Of Hiv In The Presence Of Zidovudine Lab

About lab

A new mechanism is proposed for the apparent breakthrough of HIV that occurs approximately 6 months after the commencement of therapy with zidovudine (AZT). It can be used to explore systemsbiology mclean1991 behaviour of hiv in dynamics and compare simulation behavior across conditions.

Runtime

Duration1
Comms Step0.1

Runs

Total0
Completed0
Failed0

Metadata

Packagemclean1991-behaviour-of-hiv-in-the-presence-of-zidovudine-lab
Created2026-05-17
Updated2026-05-17
epidemiologypharmacologysystemsbiologysbmlbiomodels_ebifaithfulcuratedvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_model_state_r",
        "label": "Initial Model State R",
        "maps_to": "systemsbiology_sbml_mclean1991_behaviour_of_hiv_in_the_presence_of_z_biomd0000000967_model.initial_model_state_r",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `R`."
      },
      {
        "name": "initial_model_state_v",
        "label": "Initial Model State V",
        "maps_to": "systemsbiology_sbml_mclean1991_behaviour_of_hiv_in_the_presence_of_z_biomd0000000967_model.initial_model_state_v",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `V`."
      },
      {
        "name": "initial_model_state_l",
        "label": "Initial Model State L",
        "maps_to": "systemsbiology_sbml_mclean1991_behaviour_of_hiv_in_the_presence_of_z_biomd0000000967_model.initial_model_state_l",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `L`."
      },
      {
        "name": "initial_model_state_e",
        "label": "Initial Model State E",
        "maps_to": "systemsbiology_sbml_mclean1991_behaviour_of_hiv_in_the_presence_of_z_biomd0000000967_model.initial_model_state_e",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `E`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_mclean1991_behaviour_of_hiv_in_the_presence_of_z_biomd0000000967_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_mclean1991_behaviour_of_hiv_in_the_presence_of_z_biomd0000000967_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_mclean1991_behaviour_of_hiv_in_the_presence_of_z_biomd0000000967_model.species_labels"
      },
      {
        "name": "model_state_r",
        "maps_to": "systemsbiology_sbml_mclean1991_behaviour_of_hiv_in_the_presence_of_z_biomd0000000967_model.model_state_r"
      },
      {
        "name": "model_state_v",
        "maps_to": "systemsbiology_sbml_mclean1991_behaviour_of_hiv_in_the_presence_of_z_biomd0000000967_model.model_state_v"
      },
      {
        "name": "model_state_l",
        "maps_to": "systemsbiology_sbml_mclean1991_behaviour_of_hiv_in_the_presence_of_z_biomd0000000967_model.model_state_l"
      },
      {
        "name": "model_state_e",
        "maps_to": "systemsbiology_sbml_mclean1991_behaviour_of_hiv_in_the_presence_of_z_biomd0000000967_model.model_state_e"
      }
    ]
  },
  "tags": [
    "epidemiology",
    "pharmacology",
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Mclean1991 Behaviour Of Hiv In The Presence Of Zidovudine Lab",
  "models": [
    {
      "path": "owned/models/systemsbiology_sbml_mclean1991_behaviour_of_hiv_in_the_presence_of_z_biomd0000000967_model",
      "alias": "systemsbiology_sbml_mclean1991_behaviour_of_hiv_in_the_presence_of_z_biomd0000000967_model",
      "provenance": {
        "owned_path": "owned/models/systemsbiology_sbml_mclean1991_behaviour_of_hiv_in_the_presence_of_z_biomd0000000967_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.systemsbiology_sbml_mclean1991_behaviour_of_hiv_in_the_presence_of_z_biomd0000000967_model_state"
      ],
      "from": "systemsbiology_sbml_mclean1991_behaviour_of_hiv_in_the_presence_of_z_biomd0000000967_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_mclean1991_behaviour_of_hiv_in_the_presence_of_z_biomd0000000967_model_summary"
      ],
      "from": "systemsbiology_sbml_mclean1991_behaviour_of_hiv_in_the_presence_of_z_biomd0000000967_model.summary"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_mclean1991_behaviour_of_hiv_in_the_presence_of_z_biomd0000000967_model_species_labels"
      ],
      "from": "systemsbiology_sbml_mclean1991_behaviour_of_hiv_in_the_presence_of_z_biomd0000000967_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "A new mechanism is proposed for the apparent breakthrough of HIV that occurs approximately 6 months after the commencement of therapy with zidovudine (AZT). It can be used to explore systemsbiology mclean1991 behaviour of hiv in dynamics and compare simulation behavior across conditions.",
  "schema_version": "2.0"
}

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