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Heiland2019 - NAD pathway model analysing the impact of NNMT on pathway dynamics and evolution Lab

About lab

Clean Biosimulant lab for systems signaling model: Heiland2019 - NAD pathway model analysing the impact of NNMT on pathway dynamics and evolution. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.

Runtime

Duration1
Comms Step0.1

Runs

Total0
Completed0
Failed0

Metadata

Packageheiland2019-nad-pathway-model-analysing-the-impact-of-nnmt-on-pa
Created2026-05-16
Updated2026-05-16
signalingsystemssystems-biologysbmlfaithfulbiomodels_ebicellular-signalingvisualisation

Manifest

{
  "io": {
    "inputs": [
      {
        "name": "initial_adp",
        "label": "Initial ADP",
        "maps_to": "signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model.initial_adp",
        "description": "Initial level of ADP. Maps to SBML symbol `ADP`; exposed as a traceable initial-condition perturbation."
      },
      {
        "name": "initial_amp",
        "label": "Initial AMP",
        "maps_to": "signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model.initial_amp",
        "description": "Initial level of AMP. Maps to SBML symbol `AMP`; exposed as a traceable initial-condition perturbation."
      },
      {
        "name": "initial_atp",
        "label": "Initial ATP",
        "maps_to": "signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model.initial_atp",
        "description": "Initial level of ATP. Maps to SBML symbol `ATP`; exposed as a traceable initial-condition perturbation."
      }
    ],
    "outputs": [
      {
        "name": "nicotinate_mononucleotide",
        "label": "nicotinate mononucleotide",
        "maps_to": "signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model.nicotinate_mononucleotide",
        "description": "nicotinate mononucleotide. Maps to SBML symbol `NaMN` and is emitted in native SBML units."
      },
      {
        "name": "nicotinamide",
        "label": "nicotinamide",
        "maps_to": "signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model.nicotinamide",
        "description": "nicotinamide. Maps to SBML symbol `NAM` and is emitted in native SBML units."
      },
      {
        "name": "nad",
        "label": "NAD",
        "maps_to": "signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model.nad",
        "description": "NAD. Maps to SBML symbol `NAD` and is emitted in native SBML units."
      },
      {
        "name": "state",
        "label": "Observable state",
        "maps_to": "signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model.state"
      },
      {
        "name": "summary",
        "label": "Simulation summary",
        "maps_to": "signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model.summary"
      },
      {
        "name": "species_labels",
        "label": "Observable labels",
        "maps_to": "signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model.species_labels"
      }
    ]
  },
  "tags": [
    "signaling",
    "systems",
    "systems-biology",
    "sbml",
    "faithful",
    "biomodels_ebi",
    "cellular-signaling"
  ],
  "title": "Heiland2019 - NAD pathway model analysing the impact of NNMT on pathway dynamics and evolution Lab",
  "models": [
    {
      "path": "owned/models/signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model",
      "alias": "signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model",
      "provenance": {
        "owned_path": "owned/models/signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model_state"
      ],
      "from": "signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model.state"
    },
    {
      "to": [
        "visualisation.signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model_summary"
      ],
      "from": "signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model.summary"
    },
    {
      "to": [
        "visualisation.signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model_species_labels"
      ],
      "from": "signaling_sbml_heiland2019_nad_pathway_model_analysing_the_impa_model1905220001_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "Clean Biosimulant lab for systems signaling model: Heiland2019 - NAD pathway model analysing the impact of NNMT on pathway dynamics and evolution. Values are native SBML quantities; equations, parameters, and initial values remain in the bundled source file.",
  "schema_version": "2.0"
}

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