Weis2014 - Data driven Mammalian Cell Cycle Model Lab

{
  "io": {
    "inputs": [],
    "outputs": [
      {
        "name": "early_response_gene_module",
        "label": "Early response gene module",
        "maps_to": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.early_response_gene_module",
        "description": "Tracks Early response gene module in the lab model via `cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.early_response_gene_module`."
      },
      {
        "name": "delayed_response_gene_module",
        "label": "Delayed response gene module",
        "maps_to": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.delayed_response_gene_module",
        "description": "Tracks Delayed response gene module in the lab model via `cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.delayed_response_gene_module`."
      },
      {
        "name": "hyperphosphorylated_rb",
        "label": "Hyperphosphorylated Rb",
        "maps_to": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.hyperphosphorylated_rb",
        "description": "Tracks Hyperphosphorylated Rb in the lab model via `cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.hyperphosphorylated_rb`."
      },
      {
        "name": "e2f_transcription_factor",
        "label": "E2F transcription factor",
        "maps_to": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.e2f_transcription_factor",
        "description": "Tracks E2F transcription factor in the lab model via `cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.e2f_transcription_factor`."
      },
      {
        "name": "phosphorylated_e2f",
        "label": "Phosphorylated E2F",
        "maps_to": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.phosphorylated_e2f",
        "description": "Tracks Phosphorylated E2F in the lab model via `cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.phosphorylated_e2f`."
      },
      {
        "name": "rb_tumor_suppressor",
        "label": "Rb tumor suppressor",
        "maps_to": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.rb_tumor_suppressor",
        "description": "Tracks Rb tumor suppressor in the lab model via `cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.rb_tumor_suppressor`."
      },
      {
        "name": "e2f_rb_complex",
        "label": "E2F-Rb complex",
        "maps_to": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.e2f_rb_complex",
        "description": "Tracks E2F-Rb complex in the lab model via `cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.e2f_rb_complex`."
      },
      {
        "name": "p_e2frb",
        "label": "P E2FRB",
        "maps_to": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.p_e2frb",
        "description": "Tracks P E2FRB in the lab model via `cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.p_e2frb`."
      },
      {
        "name": "act_cyclin_d",
        "label": "Act Cyclin D",
        "maps_to": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.act_cyclin_d",
        "description": "Tracks Act Cyclin D in the lab model via `cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.act_cyclin_d`."
      },
      {
        "name": "tri_d",
        "label": "Tri D",
        "maps_to": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.tri_d",
        "description": "Tracks Tri D in the lab model via `cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.tri_d`."
      },
      {
        "name": "act_cyclin_acdk1",
        "label": "Act Cyclin ACdk1",
        "maps_to": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.act_cyclin_acdk1",
        "description": "Tracks Act Cyclin ACdk1 in the lab model via `cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.act_cyclin_acdk1`."
      },
      {
        "name": "act_cyclin_acdk2",
        "label": "Act Cyclin ACdk2",
        "maps_to": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.act_cyclin_acdk2",
        "description": "Tracks Act Cyclin ACdk2 in the lab model via `cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.act_cyclin_acdk2`."
      },
      {
        "name": "act_cyclin_b",
        "label": "Act Cyclin B",
        "maps_to": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.act_cyclin_b",
        "description": "Tracks Act Cyclin B in the lab model via `cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.act_cyclin_b`."
      },
      {
        "name": "act_cyclin_e",
        "label": "Act Cyclin E",
        "maps_to": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.act_cyclin_e",
        "description": "Tracks Act Cyclin E in the lab model via `cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.act_cyclin_e`."
      },
      {
        "name": "cyclin_a",
        "label": "Cyclin A",
        "maps_to": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.cyclin_a",
        "description": "Tracks Cyclin A in the lab model via `cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.cyclin_a`."
      },
      {
        "name": "cyclin_b",
        "label": "Cyclin B",
        "maps_to": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.cyclin_b",
        "description": "Tracks Cyclin B in the lab model via `cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.cyclin_b`."
      },
      {
        "name": "cyclin_e",
        "label": "Cyclin E",
        "maps_to": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.cyclin_e",
        "description": "Tracks Cyclin E in the lab model via `cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.cyclin_e`."
      },
      {
        "name": "cyclin_dependent_kinase_inhibitor",
        "label": "Cyclin-dependent kinase inhibitor",
        "maps_to": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.cyclin_dependent_kinase_inhibitor",
        "description": "Tracks Cyclin-dependent kinase inhibitor in the lab model via `cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.cyclin_dependent_kinase_inhibitor`."
      },
      {
        "name": "cdh1_apc_c_activator",
        "label": "Cdh1 APC/C activator",
        "maps_to": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.cdh1_apc_c_activator",
        "description": "Tracks Cdh1 APC/C activator in the lab model via `cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.cdh1_apc_c_activator`."
      },
      {
        "name": "pre_mpf",
        "label": "Pre MPF",
        "maps_to": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.pre_mpf",
        "description": "Tracks Pre MPF in the lab model via `cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.pre_mpf`."
      },
      {
        "name": "tri_a",
        "label": "Tri A",
        "maps_to": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.tri_a",
        "description": "Tracks Tri A in the lab model via `cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.tri_a`."
      },
      {
        "name": "phosphorylated_apc_c_c",
        "label": "Phosphorylated APC/C/C",
        "maps_to": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.phosphorylated_apc_c_c",
        "description": "Tracks Phosphorylated APC/C/C in the lab model via `cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.phosphorylated_apc_c_c`."
      },
      {
        "name": "active_cdc20",
        "label": "Active Cdc20",
        "maps_to": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.active_cdc20",
        "description": "Tracks Active Cdc20 in the lab model via `cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.active_cdc20`."
      },
      {
        "name": "total_cdc20_apc_c_activator",
        "label": "Total Cdc20 APC/C activator",
        "maps_to": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.total_cdc20_apc_c_activator",
        "description": "Tracks Total Cdc20 APC/C activator in the lab model via `cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.total_cdc20_apc_c_activator`."
      },
      {
        "name": "mass",
        "label": "Mass",
        "maps_to": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.mass",
        "description": "Tracks Mass in the lab model via `cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.mass`."
      }
    ]
  },
  "title": "Weis2014 - Data driven Mammalian Cell Cycle Model Lab",
  "models": [
    {
      "path": "owned/models/cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model",
      "alias": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model",
      "provenance": {
        "owned_path": "owned/models/cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model_state"
      ],
      "from": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.state"
    },
    {
      "to": [
        "visualisation.cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model_summary"
      ],
      "from": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.summary"
    },
    {
      "to": [
        "visualisation.cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model_species_labels"
      ],
      "from": "cellcycle_sbml_weis2014_data_driven_mammalian_cell_cycle_model_biomd0000000723_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 10,
    "initial_inputs": {},
    "communication_step": 1
  },
  "description": "Single-model lab wrapper for Weis2014 - Data driven Mammalian Cell Cycle Model. This a model from the article: A Data-Driven, Mathematical Model of Mammalian Cell Cycle Regulation. It can be used to explore cell-cycle regulation dynamics and compare checkpoint behavior across conditions.",
  "schema_version": "2.0"
}