Yuraszeck2010 Vulnerabilities In The Tau Network In Tau Pathophysiology Lab

{
  "io": {
    "inputs": [
      {
        "name": "initial_model_state_adp",
        "label": "Initial Model State ADP",
        "maps_to": "systemsbiology_sbml_yuraszeck2010_vulnerabilities_in_the_tau_network_biomd0000000542_model.initial_model_state_adp",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `ADP`."
      },
      {
        "name": "initial_model_state_atp",
        "label": "Initial Model State ATP",
        "maps_to": "systemsbiology_sbml_yuraszeck2010_vulnerabilities_in_the_tau_network_biomd0000000542_model.initial_model_state_atp",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `ATP`."
      },
      {
        "name": "initial_tau_n_4_r",
        "label": "Initial Tau N 4 R",
        "maps_to": "systemsbiology_sbml_yuraszeck2010_vulnerabilities_in_the_tau_network_biomd0000000542_model.initial_tau_n_4_r",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `TauN_4R`."
      },
      {
        "name": "initial_tau_n_3_r",
        "label": "Initial Tau N 3 R",
        "maps_to": "systemsbiology_sbml_yuraszeck2010_vulnerabilities_in_the_tau_network_biomd0000000542_model.initial_tau_n_3_r",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `TauN_3R`."
      },
      {
        "name": "initial_tau_h4_r_hsp90",
        "label": "Initial Tau H4 R Hsp90",
        "maps_to": "systemsbiology_sbml_yuraszeck2010_vulnerabilities_in_the_tau_network_biomd0000000542_model.initial_tau_h4_r_hsp90",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `TauH4R_Hsp90`."
      },
      {
        "name": "initial_tau_h4_r_hsc70",
        "label": "Initial Tau H4 R Hsc70",
        "maps_to": "systemsbiology_sbml_yuraszeck2010_vulnerabilities_in_the_tau_network_biomd0000000542_model.initial_tau_h4_r_hsc70",
        "description": "Source state initial condition exposed as a model-specific control because no explicit intervention parameter is identifiable. Maps to SBML symbol `TauH4R_Hsc70`."
      }
    ],
    "outputs": [
      {
        "name": "state",
        "maps_to": "systemsbiology_sbml_yuraszeck2010_vulnerabilities_in_the_tau_network_biomd0000000542_model.state"
      },
      {
        "name": "summary",
        "maps_to": "systemsbiology_sbml_yuraszeck2010_vulnerabilities_in_the_tau_network_biomd0000000542_model.summary"
      },
      {
        "name": "species_labels",
        "maps_to": "systemsbiology_sbml_yuraszeck2010_vulnerabilities_in_the_tau_network_biomd0000000542_model.species_labels"
      },
      {
        "name": "adp",
        "maps_to": "systemsbiology_sbml_yuraszeck2010_vulnerabilities_in_the_tau_network_biomd0000000542_model.adp"
      },
      {
        "name": "atp",
        "maps_to": "systemsbiology_sbml_yuraszeck2010_vulnerabilities_in_the_tau_network_biomd0000000542_model.atp"
      },
      {
        "name": "tau_n_4_r",
        "maps_to": "systemsbiology_sbml_yuraszeck2010_vulnerabilities_in_the_tau_network_biomd0000000542_model.tau_n_4_r"
      },
      {
        "name": "tau_n_3_r",
        "maps_to": "systemsbiology_sbml_yuraszeck2010_vulnerabilities_in_the_tau_network_biomd0000000542_model.tau_n_3_r"
      },
      {
        "name": "tau_h4_r_hsp90",
        "maps_to": "systemsbiology_sbml_yuraszeck2010_vulnerabilities_in_the_tau_network_biomd0000000542_model.tau_h4_r_hsp90"
      },
      {
        "name": "tau_h4_r_hsc70",
        "maps_to": "systemsbiology_sbml_yuraszeck2010_vulnerabilities_in_the_tau_network_biomd0000000542_model.tau_h4_r_hsc70"
      }
    ]
  },
  "tags": [
    "physiology",
    "signaling",
    "systemsbiology",
    "sbml",
    "biomodels_ebi",
    "faithful",
    "curated"
  ],
  "title": "Yuraszeck2010 Vulnerabilities In The Tau Network In Tau Pathophysiology Lab",
  "models": [
    {
      "path": "owned/models/systemsbiology_sbml_yuraszeck2010_vulnerabilities_in_the_tau_network_biomd0000000542_model",
      "alias": "systemsbiology_sbml_yuraszeck2010_vulnerabilities_in_the_tau_network_biomd0000000542_model",
      "provenance": {
        "owned_path": "owned/models/systemsbiology_sbml_yuraszeck2010_vulnerabilities_in_the_tau_network_biomd0000000542_model"
      }
    },
    {
      "path": "owned/models/visualisation",
      "alias": "visualisation",
      "provenance": {
        "owned_path": "owned/models/visualisation"
      }
    }
  ],
  "wiring": [
    {
      "to": [
        "visualisation.systemsbiology_sbml_yuraszeck2010_vulnerabilities_in_the_tau_network_biomd0000000542_model_state"
      ],
      "from": "systemsbiology_sbml_yuraszeck2010_vulnerabilities_in_the_tau_network_biomd0000000542_model.state"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_yuraszeck2010_vulnerabilities_in_the_tau_network_biomd0000000542_model_summary"
      ],
      "from": "systemsbiology_sbml_yuraszeck2010_vulnerabilities_in_the_tau_network_biomd0000000542_model.summary"
    },
    {
      "to": [
        "visualisation.systemsbiology_sbml_yuraszeck2010_vulnerabilities_in_the_tau_network_biomd0000000542_model_species_labels"
      ],
      "from": "systemsbiology_sbml_yuraszeck2010_vulnerabilities_in_the_tau_network_biomd0000000542_model.species_labels"
    }
  ],
  "runtime": {
    "duration": 1,
    "initial_inputs": {},
    "communication_step": 0.1
  },
  "description": "Yuraszeck2010 - Vulnerabilities in the TauNetwork in Tau Pathophysiology This model is described in the article: Vulnerabilities in the tau network and the role of ultrasensitive points in tau pathoph. It can be used to explore systemsbiology yuraszeck2010 vulnerabilities in the tau dynamics and compare simulation behavior across conditions.",
  "schema_version": "2.0"
}